Mr Colin D Bicknell BM MD FRCS

1. Improving the safety of patients undergoing vascular treatments
2. Simulation, training and generation of high performing teams
3. Developing and understanding the role of new technologies to allow more patients to be treated with improved outcomes
4. Defining the required technical and non-technical skills needed in vascular and endovascular procedures
5. Outcomes research in Aortic Disease - Studies to understand the inequality that exists in outcome for men and women being treated for aortic conditions
6. Aortic Clinical Studies/Trials:
   • AARDVARK TRIAL (HTA funded), evaluating the role of ACE inhibitors to slow the growth of aneurysms.
   • The IDEAS trial (HS&DR NIHR funded) - Incentives in Diabetic Eye Assessment by Screening (IDEAS) Trial assessed the effectiveness of different incentives to improve the attendance at screening.
   • The Late aneurysm-related mortality up to 15 years, secondary endovascular repair late sac rupture risk and costs and cost-effectiveness implications in the United Kingdom EndoVascular Aneurysm Repair randomised controlled trials (funded by the Health Technology Assessment programme).
   • The UK COMPASS Study (HTA funded), A large scale study to compare treatments for juxtarenal aneurysm repair is currently ongoing.
   • The CLEVAR Registry (Industry funded, GORE), a multicentre evaluation of a novel, conformable EVAR graft, with the British Society of Endovascular Therapy.
   • STAR - The Uptake, Clinical effectiveness, Acceptability and Cost effectiveness of 23-hour EVAR

The British Society of Endovascular Therapy -ConformabLe EndoVascular Aneurysm Repair Registry: A prospective, multi-centre, observational cohort study. Funding from WL GORE and associates. Principal Investigator: Colin Bicknell

An analysis of linked Secondary and Primary Healthcare datasets to evaluate the management of hypertension and its’ impact on long-term outcomes in patients with Type B aortic dissection in the United Kingdom. BRC Cardiovascular funding stream. Principal Investigator: Colin Bicknell

 A Risk-adjusted and Anatomically Stratified Cohort Comparison Study of Open Surgery, Endovascular Techniques and Medical Management for Juxtarenal Aortic Aneurysms: The UK COMplex AneurySm Study (UK-COMPASS). Start date Jan 2017. NIHR HTA. Principal Investigator: Srinivasa Vallabhaneni, Co-investigator: Colin Bicknell