Imperial College London

DrDavidAanensen

Faculty of MedicineSchool of Public Health

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 3896d.aanensen Website

 
 
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Location

 

G30Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Argimón:2016:10.1099/mgen.0.000093,
author = {Argimón, S and Abudahab, K and Goater, RJE and Fedosejev, A and Bhai, J and Glasner, C and Feil, EJ and Holden, MTG and Yeats, CA and Grundmann, H and Spratt, B and Aanensen, DM},
doi = {10.1099/mgen.0.000093},
journal = {Microbial Genomics},
title = {Microreact: visualizing and sharing data for genomic epidemiology and phylogeography},
url = {http://dx.doi.org/10.1099/mgen.0.000093},
volume = {2},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Visualization is frequently used to aid our interpretation of complex datasets. Within microbial genomics, visualizing the relationships between multiple genomes as a tree provides a framework onto which associated data (geographical, temporal, phenotypic and epidemiological) are added to generate hypotheses and to explore the dynamics of the system under investigation. Selected static images are then used within publications to highlight the key findings to a wider audience. However, these images are a very inadequate way of exploring and interpreting the richness of the data. There is, therefore, a need for flexible, interactive software that presents the population genomic outputs and associated data in a user-friendly manner for a wide range of end users, from trained bioinformaticians to front-line epidemiologists and health workers. Here, we present Microreact, a web application for the easy visualization of datasets consisting of any combination of trees, geographical, temporal and associated metadata. Data files can be uploaded to Microreact directly via the web browser or by linking to their location (e.g. from Google Drive/Dropbox or via API), and an integrated visualization via trees, maps, timelines and tables provides interactive querying of the data. The visualization can be shared as a permanent web link among collaborators, or embedded within publications to enable readers to explore and download the data. Microreact can act as an end point for any tool or bioinformatic pipeline that ultimately generates a tree, and provides a simple, yet powerful, visualization method that will aid research and discovery and the open sharing of datasets.
AU - Argimón,S
AU - Abudahab,K
AU - Goater,RJE
AU - Fedosejev,A
AU - Bhai,J
AU - Glasner,C
AU - Feil,EJ
AU - Holden,MTG
AU - Yeats,CA
AU - Grundmann,H
AU - Spratt,B
AU - Aanensen,DM
DO - 10.1099/mgen.0.000093
PY - 2016///
SN - 2057-5858
TI - Microreact: visualizing and sharing data for genomic epidemiology and phylogeography
T2 - Microbial Genomics
UR - http://dx.doi.org/10.1099/mgen.0.000093
UR - http://hdl.handle.net/10044/1/43060
VL - 2
ER -