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@article{Wang:2020:10.1007/s00125-020-05214-4,
author = {Wang, Y and Huang, W and O'Neil, A and Lan, Y and Aune, D and Wang, W and Yu, C and Chen, X},
doi = {10.1007/s00125-020-05214-4},
journal = {Diabetologia},
pages = {2292--2304},
title = {Association between sleep duration and mortality risk among adults with type 2 diabetes: a prospective cohort study},
url = {http://dx.doi.org/10.1007/s00125-020-05214-4},
volume = {63},
year = {2020}
}

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TY  - JOUR
AB  - AIMS/HYPOTHESIS: This study aimed to investigate whether the effects of sleep duration interacted with the presence of diabetes. We specifically sought to examine the relationship between sleep duration and all-cause and cause-specific mortality in people with type 2 diabetes across sex, age at diagnosis, duration of diabetes and treatment type. METHODS: The sample consisted of 273,029 adults, including 248,817 without diabetes and 24,212 with type 2 diabetes, who participated in the National Health Interview Survey from 2004 to 2013 and whose data were linked to a mortality database up to 31 December 2015. Sleep duration was measured using self-report, whereby participants were asked 'on average how long do you sleep each day (≤5, 6, 7, 8, 9 or ≥10 h/day)?' The relationship between sleep duration and mortality risk was investigated using Cox proportional hazards regression model, with adjustments for demographics, BMI, lifestyle behaviours and clinical variables. RESULTS: Absolute mortality rate was higher in adults with diabetes and extremes of sleep duration (≤5 h/day, 215.0 per 10,000 person-years; ≥10 h/day, 363.5 per 10,000 person-years). There was a non-significant interaction between sleep duration and the presence of diabetes (p for interaction = 0.08). A J-shaped relationship existed between sleep duration and all-cause mortality risk in people with type 2 diabetes. Compared with the reference group (7 h/day), both shorter and longer sleep durations were associated with increased risk of all-cause mortality (≤5 h/day, HR 1.24 [95% CI 1.09, 1.40]; 6 h/day, HR 1.13 [1.01, 1.28]; 8 h/day, HR 1.17 [1.06, 1.30]; ≥10 h/day, HR 1.83 [1.61, 2.08]). Similar associations were also observed for mortality risk from CVD, cancer, kidney disease, Alzheimer's disease and chronic lower respiratory diseases. Longer sleep duration in those with a younger age at diabetes onset was associated with greater risks
AU  - Wang,Y
AU  - Huang,W
AU  - O'Neil,A
AU  - Lan,Y
AU  - Aune,D
AU  - Wang,W
AU  - Yu,C
AU  - Chen,X
DO  - 10.1007/s00125-020-05214-4
EP  - 2304
PY  - 2020///
SN  - 0012-186X
SP  - 2292
TI  - Association between sleep duration and mortality risk among adults with type 2 diabetes: a prospective cohort study
T2  - Diabetologia
UR  - http://dx.doi.org/10.1007/s00125-020-05214-4
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32671413
UR  - https://link.springer.com/article/10.1007%2Fs00125-020-05214-4
UR  - http://hdl.handle.net/10044/1/81096
VL  - 63
ER  -

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