Imperial College London
Professor Don Craig

ProfessorDonCraig

Faculty of Natural Sciences, Department of Chemistry

Professor of Organic Synthesis
 
 
 
//

Contact

 

+44 (0)20 7594 5771d.craig Website

 
 
//

Location

 

501DMolecular Sciences Research HubWhite City Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Craig:2020:10.1039/d0cc04413j,
author = {Craig, D and Spreadbury, SRJ and White, AJP},
doi = {10.1039/d0cc04413j},
journal = {Chemical Communications},
pages = {9803--9806},
title = {Synthesis and hetero-diels–alder reactions of enantiomerically pure dihydro-1H-azepines},
url = {http://dx.doi.org/10.1039/d0cc04413j},
volume = {56},
year = {2020}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Thermolysis of enantiomerically pure 3-substituted 7,7-dihalo-2-azabicyclo[4.1.0]heptanes in the presence of K2CO3 gives in good yields 2-alkyl-6-halo-1-tosyl-2,3-dihydro-1H-azepines. These undergo highly stereoselective [4+2] cycloaddition reactions with heterodienophiles and arylation/alkenylation under Suzuki conditions.
AU  - Craig,D
AU  - Spreadbury,SRJ
AU  - White,AJP
DO  - 10.1039/d0cc04413j
EP  - 9806
PY  - 2020///
SN  - 1359-7345
SP  - 9803
TI  - Synthesis and hetero-diels–alder reactions of enantiomerically pure dihydro-1H-azepines
T2  - Chemical Communications
UR  - http://dx.doi.org/10.1039/d0cc04413j
UR  - https://pubs.rsc.org/en/content/articlelanding/2020/CC/D0CC04413J#!divAbstract
UR  - http://hdl.handle.net/10044/1/81391
VL  - 56
ER  -
Download