Publications
191 results found
Elson D, Requejo-Isidro J, Munro I, et al., 2004, Time-domain fluorescence lifetime imaging applied to biological tissue, Photochemical & Photobiological Sciences, Vol: 3, Pages: 795-801, ISSN: 1474-905X
Davis DM, Igakura T, McCann FE, et al., 2003, The protean immune cell synapse:: a supramolecular structure with many functions, SEMINARS IN IMMUNOLOGY, Vol: 15, Pages: 317-324, ISSN: 1044-5323
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- Citations: 22
Artavanis-Tsakonas K, Eleme K, McQueen KL, et al., 2003, Activation of a subset of human NK cells upon contact with <i>Plasmodium falciparum</i>-infected erythrocytes, JOURNAL OF IMMUNOLOGY, Vol: 171, Pages: 5396-5405, ISSN: 0022-1767
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- Citations: 158
McCann FE, Vanherberghen B, Eleme K, et al., 2003, The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses, JOURNAL OF IMMUNOLOGY, Vol: 170, Pages: 2862-2870, ISSN: 0022-1767
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- Citations: 90
Suhling K, Elson DS, Siegel J, et al., 2003, Fluorescence Lifetime Imaging for Biomedicine
Fluorescence lifetime imaging (FLIM) provides potentially compact and robust time-domain instrumentation for real-world application to permit non-invasive differentiation between different types or states of tissue autofluorescence. It also permits imaging of the local environment of fluorescence labels, such as GFP applied to study molecular recognition and protein trafficking in cells, and it provides new opportunities for assays of micro-arrays. Wide-field FLIM combined with spectral and polarization discrimination provides enhanced functional contrast at high-speed.
Siegel J, Suhling K, Lévêque-Fort S, et al., 2003, Wide-field time-resolved fluorescence anisotropy imaging (TR-FAIM):: Imaging the rotational mobility of a fluorophore, REVIEW OF SCIENTIFIC INSTRUMENTS, Vol: 74, Pages: 182-192, ISSN: 0034-6748
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- Citations: 76
Suhling K, Siegel J, Leveque-Fort S, et al., 2003, Mapping the rotational diffusion of fluorophores in cells with time-resolved wide-field fluorescence anisotropy imaging, Piscataway, NJ, CLEO/Europe. 2003 conference on lasers and electro-optics Europe, 2003, 22 - 27 June 2003, Publisher: IEEE, Pages: 709-709
Suhling K, Siegel J, Phillips D, et al., 2002, Imaging the environment of green fluorescent protein, BIOPHYSICAL JOURNAL, Vol: 83, Pages: 3589-3595, ISSN: 0006-3495
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- Citations: 213
McCann FE, Suhling K, Carlin LM, et al., 2002, Imaging immune surveillance by T cells and NK cells, IMMUNOLOGICAL REVIEWS, Vol: 189, Pages: 179-192, ISSN: 0105-2896
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- Citations: 21
Davis DM, 2002, Assembly of the immunological synapse for T cells and NK cells, TRENDS IN IMMUNOLOGY, Vol: 23, Pages: 356-363, ISSN: 1471-4906
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- Citations: 107
Elson DS, Siegel J, Webb SED, et al., 2002, Wide-field fluorescence lifetime imaging with optical sectioning and spectral resolution applied to biological samples, 15th National Quanturn Electronics and Photonics Conference, Publisher: TAYLOR & FRANCIS LTD, Pages: 985-995, ISSN: 0950-0340
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- Citations: 15
Suhling K, Davis DM, Phillips D, 2002, The influence of solvent viscosity on the fluorescence decay and time-resolved anisotropy of green fluorescent protein, 7th Conference on Methods and Applications of Fluorescence: Spectroscopy Imaging and Probes (MAF), Publisher: SPRINGER/PLENUM PUBLISHERS, Pages: 91-95, ISSN: 1053-0509
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- Citations: 55
Elson D, Webb S, Siegel J, et al., 2002, Biomedical applications of fluorescence lifetime imaging, Optics and Photonics News, Vol: 13, Pages: 26-33, ISSN: 1047-6938
Suhling K, Davis DM, Phillips D, et al., 2002, Probing the local environment of green fluorescent protein (GFP) with fluorescence lifetime imaging (FLIM) and time-resolved fluorescence anisotropy imaging (tr-FAIM) (WD1), Biomedical topical meetings, Miami Beach, Florida, April 2002, Publisher: Optical Society of America
Fassett MS, Davis DM, Valter MM, et al., 2001, Signaling at the inhibitory natural killer cell immune synapse regulates lipid raft polarization but not class I MHC clustering, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 98, Pages: 14547-14552, ISSN: 0027-8424
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- Citations: 92
Carlin LM, Eleme K, McCann FE, et al., 2001, Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 194, Pages: 1507-1517, ISSN: 0022-1007
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- Citations: 152
Mandelboim O, Lieberman N, Lev M, et al., 2001, Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells, NATURE, Vol: 409, Pages: 1055-1060, ISSN: 0028-0836
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- Citations: 724
Baba E, Erskine R, Boyson JE, et al., 2000, N-linked carbohydrate on human leukocyte antigen-C and recognition by natural killer cell inhibitory receptors, HUMAN IMMUNOLOGY, Vol: 61, Pages: 1202-1218, ISSN: 0198-8859
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- Citations: 15
Gakamsky DM, Davis DM, Strominger JL, et al., 2000, Assembly and dissociation of human leukocyte antigen (HLA)-A2 studied by real-time fluorescence resonance energy transfer, BIOCHEMISTRY, Vol: 39, Pages: 11163-11169, ISSN: 0006-2960
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- Citations: 28
Davis DM, 2000, Molecular recognition of disease at natural killer cell immune synapses., Sci Prog, Vol: 83, Pages: 303-316, ISSN: 0036-8504
An emerging theme in contemporary molecular immunology is that a knowledge of protein structures and the physical chemistry of soluble receptor/ligand pairs is insufficient to predict the outcome of intercellular communication. Cell surface receptors need to be considered as part of supramolecular complexes of proteins and lipids that facilitate specific receptor conformations and distinct distributions at cell surfaces. As cells of the immune system survey other cells for signatures of disease, proteins accumulate and organise in distinct patterns at the contact regions between the cells. The intercellular organisation of proteins by which a cell's state of health is relayed has been termed the immune or immunological synapse. That different arrangements of segregated protein domains can occur at immune synapses raises a number of important questions. For example does supramolecular organisation of the synapse influence the outcome of the intercellular communication and how is the organisation of protein at immune synapses biophysically controlled?
Davis DM, Chiu I, Fassett M, et al., 1999, The human natural killer cell immune synapse, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 96, Pages: 15062-15067, ISSN: 0027-8424
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- Citations: 346
Chiu I, Davis DM, Strominger JL, 1999, Trafficking of spontaneously endocytosed MHC proteins, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 96, Pages: 13944-13949, ISSN: 0027-8424
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- Citations: 42
Gakamsky DM, Boyd LF, Margulies DH, et al., 1999, An allosteric mechanism controls antigen presentation by the H-2K<SUP>b</SUP> complex, BIOCHEMISTRY, Vol: 38, Pages: 12165-12173, ISSN: 0006-2960
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- Citations: 25
Pazmany L, Mandelboim O, Vales-Gomez M, et al., 1999, Human leucocyte antigen-G and its recognition by natural killer cells, JOURNAL OF REPRODUCTIVE IMMUNOLOGY, Vol: 43, Pages: 127-137, ISSN: 0165-0378
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- Citations: 18
Cohen GB, Gandhi RT, Davis DM, et al., 1999, The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells, IMMUNITY, Vol: 10, Pages: 661-671, ISSN: 1074-7613
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- Citations: 706
Mandelboim O, Malik P, Davis DM, et al., 1999, Human CD16 as a lysis receptor mediating direct natural killer cell cytotoxicity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 96, Pages: 5640-5644, ISSN: 0027-8424
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- Citations: 203
Davis DM, Mandelboim O, Luque I, et al., 1999, The transmembrane sequence of human histocompatibility leukocyte antigen (HLA)-C as a determinant in inhibition of a subset of natural killer cells, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 189, Pages: 1265-1274, ISSN: 0022-1007
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- Citations: 28
Gakamsky DM, Davis DM, Haas E, et al., 1999, Photophysical analysis of class I major histocompatibility complex protein assembly using a xanthene-derivatized β<sub>2</sub>-microglobulin, BIOPHYSICAL JOURNAL, Vol: 76, Pages: 1552-1560, ISSN: 0006-3495
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- Citations: 10
Mandelboim O, Kent S, Davis DM, et al., 1998, Natural killer activating receptors trigger interferon γ secretion from T cells and natural killer cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 95, Pages: 3798-3803, ISSN: 0027-8424
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- Citations: 58
Mandelboim O, Pazmany L, Davis DM, et al., 1997, Multiple receptors for HLA-G on human natural killer cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 94, Pages: 14666-14670, ISSN: 0027-8424
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- Citations: 70
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