Imperial College London
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ProfessorDarioFarina

Faculty of Engineering, Department of Bioengineering

Chair in Neurorehabilitation Engineering
 
 
 
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Contact

 

+44 (0)20 7594 1387d.farina Website

 
 
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Location

 

RSM 4.15Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Muceli:2019:1741-2552/ab047a,
author = {Muceli, S and Poppendieck, W and Hoffmann, K and Dosen, S and Benito-Leon, J and Barroso, FO and Pons, JL and Farina, D},
doi = {1741-2552/ab047a},
journal = {Journal of Neural Engineering},
title = {A thin-film multichannel electrode for muscle recording and stimulation in neuroprosthetics applications},
url = {http://dx.doi.org/10.1088/1741-2552/ab047a},
volume = {16},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objective. We propose, design and test a novel thin-film multichannel electrode that can be used for both recording from and stimulating a muscle in acute implants. Approach. The system is built on a substrate of polyimide and contains 12 recording and three stimulation sites made of platinum. The structure is 420 µm wide, 20 µm thick and embeds the recording and stimulation contacts on the two sides of the polyimide over an approximate length of 2 cm. We show representative applications in healthy individuals as well as tremor patients. The designed system was tested by a psychometric characterization of the stimulation contacts in six tremor patients and three healthy individuals determining the perception threshold and current limit as well as the success rate in discriminating elicited sensations (electrotactile feedback). Also, we investigated the possibility of using the intramuscular electrode for reducing tremor in one patient by electrical stimulation delivered with timing based on the electromyographic activity recorded with the same electrode. Main results. In the tremor patients, the current corresponding to the perception threshold and the current limit were 0.7  ±  0.2 and 1.4  ±  0.7 mA for the wrist flexor muscles and 0.4  ±  0.2 and 1.5  ±  0.7 mA for the extensors. In one patient, closed-loop stimulation resulted in a decrease of the tremor power  >50%. In healthy individuals the perception threshold and current limits were 0.9  ±  0.6 and 2.1  ±  0.6 mA for the extensor carpi radialis muscle. The subjects could distinguish four or six stimulation patterns (two or three stimulation sites  ×  two stimulation current amplitudes) with true positive rate  >80%
AU  - Muceli,S
AU  - Poppendieck,W
AU  - Hoffmann,K
AU  - Dosen,S
AU  - Benito-Leon,J
AU  - Barroso,FO
AU  - Pons,JL
AU  - Farina,D
DO  - 1741-2552/ab047a
PY  - 2019///
SN  - 1741-2552
TI  - A thin-film multichannel electrode for muscle recording and stimulation in neuroprosthetics applications
T2  - Journal of Neural Engineering
UR  - http://dx.doi.org/10.1088/1741-2552/ab047a
UR  - http://hdl.handle.net/10044/1/67437
VL  - 16
ER  -
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