Publications
431 results found
Varghese A, Merrifield RD, Crowe LA, et al., 2006, Evaluation of carotid artery wall volume measurement using novel semiautomated analysis software, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 24, Pages: 1401-1408, ISSN: 1053-1807
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- Citations: 13
Sen-Chowdhry S, Prasad SK, Syrris P, et al., 2006, Cardiovascular magnetic resonance in arrhythmogenic right ventricular cardiomyopathy revisited - Comparison with task force criteria and genotype, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 48, Pages: 2132-2140, ISSN: 0735-1097
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- Citations: 149
Gatehouse P, Lyne J, Smith G, et al., 2006, T2* effects in the dual-sequence method for high-dose first-pass myocardial perfusion, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 24, Pages: 1168-1171, ISSN: 1053-1807
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- Citations: 10
Tanner MA, He T, Westwood MA, et al., 2006, Multi-center validation of the transferability of the magnetic resonance T2*technique for the quantification of tissue iron, HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, Vol: 91, Pages: 1388-1391, ISSN: 0390-6078
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- Citations: 45
Tanner MA, He T, Westwood MA, et al., 2006, Multi-center validation of the transferability of the magnetic resonance T2*technique for the quantification of tissue iron, HAEMATOLOGICA, Vol: 91, Pages: 1388-1391, ISSN: 0390-6078
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- Citations: 118
Terrovitis JV, Bulte JWM, Sarvananthan S, et al., 2006, Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering., Tissue Eng, Vol: 12, Pages: 2765-2775, ISSN: 1076-3279
Mesenchymal stem cells (MSCs) are a promising candidate cell for tissue engineering. Magnetic resonance imaging (MRI) has been proven effective in visualizing iron-labeled stem cells; however, the efficiency of this approach for visualization of cells seeded on scaffolds intended for use as tissue-engineered heart valves has not been assessed. MSCs were labeled by incubating for 48 h with ferumoxide and poly-L-lysine as transfecting agent. Any detrimental effect of iron labeling on cell viability, proliferation, and differentiation was examined using appropriate functional assays. Change in the nuclear magnetic relaxation properties of labeled cells was determined using in vitro relaxometry of cells seeded in 3-dimensional collagen gels. Images of labeled and non-labeled cells seeded onto 1% type I bovine collagen scaffolds were obtained using MRI. The presence of intracellular iron in labeled cells was demonstrated using Prussian blue staining, confocal microscopy, and electron microscopy. Cell viability, proliferation, and differentiation were comparable in labeled and non-labeled cells. The T2 relaxation time was 40% to 50% shorter in ferumoxide-labeled cells. Labeled cells seeded on scaffolds appeared as areas of reduced signal intensity in T2 weighted images. Ferumoxide labeling persisted and remained effective even on scans performed 4 weeks after the labeling procedure. Ferumoxide labeling of human MSCs seeded on collagen scaffolds is an effective, non-toxic technique for visualization of these cells using MRI. This technique appears promising for cell tracking in future tissue-engineering applications.
Terrovitis JV, Bulte JWM, Sarvananthan S, et al., 2006, Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds - Relevance to tissue engineering, TISSUE ENGINEERING, Vol: 12, Pages: 2765-2775, ISSN: 2152-4947
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- Citations: 65
Keegan J, Gatehouse PD, Prasad SK, et al., 2006, Improved turbo spin-echo imaging of the heart with motion-tracking, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 24, Pages: 563-570, ISSN: 1053-1807
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- Citations: 33
He T, Gatehouse PD, Anderson LJ, et al., 2006, Development of a novel optimized breathhold technique for myocardial T2 measurement in thalassemia, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 24, Pages: 580-585, ISSN: 1053-1807
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- Citations: 60
Lee KL, Doorly DJ, Firmin DN, 2006, Numerical simulations of phase contrast velocity mapping of complex flows in an anatomically realistic bypass graft geometry, MEDICAL PHYSICS, Vol: 33, Pages: 2621-2631, ISSN: 0094-2405
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- Citations: 17
Lyne J, Gatehouse P, Assomull R, et al., 2006, Cardiovascular magnetic resonance myocardial perfusion imaging: Comparison of three sequences with parallel acquisition, Annual Scientific Conference of the British-Society-Promoting-Cardiovascular-Health, Publisher: B M J PUBLISHING GROUP, Pages: A102-A103, ISSN: 1355-6037
Crowe L, Varghese A, Mohiaddin R, et al., 2006, Elimination of residual blood flow-related signal in 3D volume-selective TSE arterial wall imaging using velocity-sensitive phase reconstruction, Journal of Magnetic Resonance Imaging, Vol: 23
Dowsey AW, Keegan J, Lerotic M, et al., 2006, Motion-Compensated MR Valve Imaging with COMB Tag Tracking and Super-Resolution Enhancement, Medical Image Computing and Computer Aided Intervention - MICCAI 2006
Dowsey AW, Keegan J, Lerotic M, et al., 2006, Motion-compensated MR valve imaging with COMB tag tracking and super-resolution enhancement, Springer-Verlag, 9th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), Copenhagen, Denmark, Publisher: Heidelberg, Pages: 364-371, ISSN: 1611-3349
MR imaging of the heart valve leaflets is a challenging problem due to their large movements throughout the cardiac cycle. This paper presents a motion-compensated imaging approach with COMB tagging for valve imaging. It involves an automatic method for tracking the full 3D motion of the valve plane so as to provide a motion-tracked acquisition scheme. Super-resolution enhancement is then applied to the slice-select direction so that the partial volume effect is minimised. In vivo results have shown that in terms of slice positioning, the method has equivalent accuracy to that of a manual approach whilst being quicker and more consistent. The use of multiple parallel COMB tags will permit adaptive imaging that follows tissue motion. This will have significant implications for quantification of myocardial perfusion and tracking anatomy, functions that are traditionally difficult in MRI.
Lee KL, Firmin DN, Doorly DJ, 2005, Assessment of MR angiography using in-vitro models and computer simulation, Proceedings of the 2005 Summer Bioengineering Conference, Vol: 2005, Pages: 711-712
Varghese A, Crowe L, Mohiaddin R, et al., 2005, Inter-study reproducibility of 3D volume selective fast spin echo sequence for quantifying carotid artery wall volume in asymptomatic subjects, Atherosclerosis, Vol: 183, Pages: 361-366
MOHIADDIN RH, GATEHOUSE PD, FIRMIN DN, 2005, EXERCISE RELATED CHANGES IN AORTIC FLOW MEASURED WITH SPIRAL ECHO-PLANAR MR VELOCITY MAPPING, JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 5, Pages: 159-163, ISSN: 1053-1807
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- Citations: 23
Taylor AM, Jhooti P, Wiesmann F, et al., 2005, MR navigator-echo monitoring of temporal changes in diaphragm position: Implications for MR coronary angiography, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 7, Pages: 629-636, ISSN: 1053-1807
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- Citations: 140
Mohiaddin RH, Gatehouse PD, Henien M, et al., 2005, Cine MR Fourier velocimetry of blood flow through cardiac valves: Comparison with Doppler echocardiography, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 7, Pages: 657-663, ISSN: 1053-1807
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- Citations: 33
Wiesmann F, Gatehouse PD, Panting JR, et al., 2005, Comparison of fast spiral, echo planar, and fast low-angle shot MRI for cardiac volumetry at .5T, JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 8, Pages: 1033-1039, ISSN: 1053-1807
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- Citations: 15
Kirk P, Anderson LJ, Tanner MA, et al., 2005, Inter-site validation of a single breath hold T2*MR technique for heart and liver iron measurement., 47th Annual Meeting of the American-Society-of-Hematology, Publisher: AMER SOC HEMATOLOGY, Pages: 38B-38B, ISSN: 0006-4971
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- Citations: 5
Kirk P, Firmin DN, Sampson B, et al., 2005, Validation of T2*technique in ex-vivo myocardial tissue., 47th Annual Meeting of the American-Society-of-Hematology, Publisher: AMER SOC HEMATOLOGY, Pages: 7B-7B, ISSN: 0006-4971
Tanner MA, He TG, Westwood MA, et al., 2005, Multi-centre validation of the cardiovascular magnetic resonance multi breath-hold T2*technique for myocardial iron quantification in thalassaemia major., 47th Annual Meeting of the American-Society-of-Hematology, Publisher: AMER SOC HEMATOLOGY, Pages: 37B-37B, ISSN: 0006-4971
Crowe L, Keegan J, Gatehouse P, et al., 2005, 3D volume-selective turbo spin echo for carotid artery wall imaging with navigator detection of swallowing, Journal of Magnetic Resonance Imaging, Vol: 22, Pages: 583-588
Gatehouse PD, Keegan J, Crowe LA, et al., 2005, Applications of phase-contrast flow and velocity imaging in cardiovascular MRI, EUROPEAN RADIOLOGY, Vol: 15, Pages: 2172-2184, ISSN: 0938-7994
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- Citations: 223
Westwood MA, Firmin DN, Gildo M, et al., 2005, Intercentre reproducibility of magnetic resonance T2*measurements of myocardial iron in thalassaemia, INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol: 21, Pages: 531-538, ISSN: 1569-5794
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- Citations: 92
Vermeersch SJ, Glor FP, Crowe LA, et al., 2005, Relationship between carotid artery intima-media thickness and wall shear stress derived parameters., Comput Methods Biomech Biomed Engin, Vol: 8, Pages: 279-280, ISSN: 1025-5842
Elkington AG, Gatehouse PD, Cannell TM, et al., 2005, Comparison of hybrid echo-planar imaging and FLASH myocardial perfusion cardiovascular MR imaging, RADIOLOGY, Vol: 235, Pages: 237-243, ISSN: 0033-8419
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- Citations: 21
Elkington AG, He TG, Gatehouse PD, et al., 2005, Optimization of the arterial input function for myocardial perfusion cardiovascular magnetic resonance, JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol: 21, Pages: 354-359, ISSN: 1053-1807
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- Citations: 23
Ariff B, Crowe L, Firmin D, et al., 2005, Comparison between three-dimensional volume-selective turbo spin-echo imaging and two-dimensional ultrasound for assessing carotid artery structure and function, Journal of Magnetic Resonance Imaging, Vol: 21
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