Publications
88 results found
Robbins-Cherry SA, Hayter M, Wylie KR, et al., 2011, The experiences of men living with inhibited ejaculation, SEXUAL AND RELATIONSHIP THERAPY, Vol: 26, Pages: 242-253, ISSN: 1468-1994
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- Citations: 5
Clayton AH, Goldmeier D, Nappi RE, et al., 2010, Validation of the Sexual Interest and Desire Inventory-Female in Hypoactive Sexual Desire Disorder, JOURNAL OF SEXUAL MEDICINE, Vol: 7, Pages: 3918-3928, ISSN: 1743-6095
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- Citations: 34
Ashby J, Pickwoad N, Vaneyk J, et al., 2010, Analysis of the sexual problems of HIV positive indivduals cared for in a London Genitourinary Medicine clinic, JOURNAL OF SEXUAL MEDICINE, Vol: 7, Pages: 457-457, ISSN: 1743-6095
Sacks R, Tipple C, Goldmeier D, 2010, Syphilitic aorta: exploring the bigger picture, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 21, Pages: 608-608, ISSN: 0956-4624
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- Citations: 1
Ashby J, Goldmeier D, 2010, Postorgasm Illness Syndrome-A Spectrum of Illnesses, JOURNAL OF SEXUAL MEDICINE, Vol: 7, Pages: 1976-1981, ISSN: 1743-6095
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- Citations: 23
Goldmeier D, 2010, Persistent genital arousal disorder Reply, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 21, Pages: 380-380, ISSN: 0956-4624
Sadeghi-Nejad H, Wasserman M, Weidner W, et al., 2010, Sexually Transmitted Diseases and Sexual Function, JOURNAL OF SEXUAL MEDICINE, Vol: 7, Pages: 389-413, ISSN: 1743-6095
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- Citations: 20
Emerson C, Goldmeier D, Green P, 2009, Assessing training in sexual dysfunction for genitourinary medicine registrars, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 20, Pages: 745-747, ISSN: 0956-4624
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- Citations: 2
Vera JH, Parkes R, Goldmeier D, 2009, Current management of syphilis infection, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 20, Pages: 810-810, ISSN: 0956-4624
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- Citations: 1
Goldmeier D, Richardson D, 2009, Is phosphodiesterase type 5 inhibitor use associated with condom breakage? Commentary, SEXUALLY TRANSMITTED INFECTIONS, Vol: 85, Pages: 405-406, ISSN: 1368-4973
Garvey L, West C, Latch N, et al., 2009, PREVALENCE OF PERSISTENT GENITAL AROUSAL (PGA) AND PERSISTENT GENITALAROUSAL DISORDER (PGAD) IN WOMEN ATTENDING A LONDON SEXUAL HEALTH CLINIC, JOURNAL OF SEXUAL MEDICINE, Vol: 6, Pages: 395-395, ISSN: 1743-6095
Garvey LJ, West C, Latch N, et al., 2009, Report of spontaneous and persistent genital arousal in women attending a sexual health clinic, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 20, Pages: 519-521, ISSN: 0956-4624
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- Citations: 25
Hames RK, Wilson C, Goldmeier D, 2009, Oral Phosphodiesterase Type 5 Inhibitors: Nonerectogenic Beneficial Uses-A Comment, JOURNAL OF SEXUAL MEDICINE, Vol: 6, Pages: 2079-2079, ISSN: 1743-6095
Crowley T, Goldmeier D, Hiller J, 2009, Diagnosing and managing vaginismus, BMJ-BRITISH MEDICAL JOURNAL, Vol: 338, ISSN: 1756-1833
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- Citations: 36
Goldmeier D, Mears A, Hiller J, et al., 2009, Persistent genital arousal disorder: a review of the literature and recommendations for management, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 20, Pages: 373-377, ISSN: 0956-4624
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- Citations: 33
Goldmeier D, 2009, PDE5i and vaginal orgasm: Reply to letter from S Brody., Int J STD AIDS, Vol: 20, Pages: 440-441, ISSN: 0956-4624
Foster R, Mears A, Goldmeier D, 2009, A literature review and case reports series on the use of phosphodiesterase inhibitors in the treatment of female sexual dysfunction, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 20, Pages: 152-157, ISSN: 0956-4624
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- Citations: 13
Goldmeier D, Mears A, 2009, Genital Responsiveness in Healthy Women-What About Subjective Genital Engorgement?, JOURNAL OF SEXUAL MEDICINE, Vol: 6, Pages: 294-294, ISSN: 1743-6095
Goldmeier D, Leiblum S, 2008, Interaction of organic and psychological factors in persistent genital arousal disorder in women: a report of six cases, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 19, Pages: 488-490, ISSN: 0956-4624
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- Citations: 23
Goldmeier D, Garvey L, Barton S, 2008, Does chronic stress lead to increased rates of recurrences of genital herpes - a review of the psychoneuroimmunological evidence?, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 19, Pages: 359-362, ISSN: 0956-4624
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- Citations: 4
Goldmeier D, 2008, Premature ejaculation and pharmaceutical company-based medicine: The dapoxetine case - Reply, JOURNAL OF SEXUAL MEDICINE, Vol: 5, Pages: 987-988, ISSN: 1743-6095
Goldmeier D, 2007, 5-HT1A receptors on oxytocin neurons and premature ejaculation--a comment., J Sex Med, Vol: 4, ISSN: 1743-6095
Richardson D, Goldmeier D, Frize G, et al., 2007, Letrozole versus testosterone. a single-center pilot study of HIV-infected men who have sex with men on highly active anti-retroviral therapy (HAART) with hypoactive sexual desire disorder and raised estradiol levels., J Sex Med, Vol: 4, Pages: 502-508, ISSN: 1743-6095
INTRODUCTION: Since the advent of Highly Active Anti-Retroviral Therapy (HAART), men with HIV experience good quality of life and expect to have normal sexual function. However, it appears that men infected with HIV commonly complain of sexual problems. There is evidence that men on HAART develop low sexual desire that is associated with raised estradiol levels. It has been postulated that abnormal metabolism seen in this group of men increases the aromatization of testosterone to estradiol. We hypothesized that letrozole, an aromatase inhibitor that inhibits the conversion of testosterone to estradiol, would be beneficial in these men. AIM: The aim of this study was to compare the effects of testosterone vs. an aromatase inhibitor, letrazole, in HIV-infected men with raised estradiol and low sexual desire. METHODS: Thirteen men who have sex with men on HAART with low sexual desire as well as raised estradiol levels (>120 pmol/L) were randomly allocated to receive either parenteral testosterone (Sustanon 250 intramuscular injection) (N = 6) or letrozole 2.5 mg orally daily (N = 7) for 6 weeks. MAIN OUTCOME MEASURES: Sex steroid hormone assays, sex hormone-binding globulin, virological, hematological, and biochemical parameters were measured before and after treatment. Each subject was given the Spector Sexual Desire Inventory and the Depression/Anxiety Stress Scale before and immediately after treatment. Subjects were also asked to estimate the number of actual sexual acts before and after treatment. Results. Inventory data showed a rise in dyadic desire in both treatment arms. Mean actual sexual acts rose from 0.33 to 1.5 in the testosterone group and from 0.43 to 1.29 for the letrozole group. Luteinizing hormone increased in seven of seven men on letrozole. Serum testosterone increased in seven of seven men on letrozole. There were no adverse events from either medication. CONCLUSION: Letrozole may be useful in the management of men on HAART who have low sexual
Bell C, Richardson D, Goldmeier D, et al., 2007, Persistent sexual arousal in a woman with associated cardiac defects and raised atrial natriuretic peptide., Int J STD AIDS, Vol: 18, Pages: 130-131, ISSN: 0956-4624
The persistent sexual arousal syndrome (PSAS) is a newly described entity where the woman becomes involuntarily genitally aroused for extended periods of time in the absence of sexual desire and is distressed by this situation. The cause of this sexual problem is not well understood. We describe such a case where the subjective feelings were confirmed by observing genital engorgement. In her case, PSAS came on after initiation of fludrocortisone given for hypotension and bradycardia that was associated with an atrial septal defect (ASD). We argue that the combined effect of the ASD and fludrocortisone may be associated with an increase in her levels of atrial natriuretic peptide (ANP). ANP causes profound vasodilation and vascular leakage. We postulate that the high serum levels of ANP in her case may be contributory to her PSAS.
Dinsmore WW, Hackett G, Goldmeier D, et al., 2007, Topical eutectic mixture for premature ejaculation (TEMPE): a novel aerosol-delivery form of lidocaine-prilocaine for treating premature ejaculation, BJU INTERNATIONAL, Vol: 99, Pages: 369-375, ISSN: 1464-4096
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- Citations: 93
Richardson D, Lamba H, Goldmeier D, et al., 2006, Factors associated with sexual dysfunction in men with HIV infection., Int J STD AIDS, Vol: 17, Pages: 764-767, ISSN: 0956-4624
Where men have had access to successful treatment for HIV (highly active antiretroviral therapy), expectations of both patients and physicians alike have changed significantly over the past decade. Such men, living with HIV, expect to lead fully functional lives including a normal sex life. Sexual dysfunction is well described among men with HIV. We retrospectively analysed details of 190 consecutive men attending a dedicated sexual dysfunction service in our HIV unit over an 18-month period. We took note of the specifics of their HIV disease, illnesses other than HIV, as well as other risk factors associated with sexual dysfunction. Men with sexual dysfunction all commonly reported recreational drug use, hepatitis B and C co-infection, anxiety and depressive illnesses, peripheral neuropathy and lipodystrophy. There was a significant relationship between men complaining of retarded ejaculation and peripheral neuropathy. Sexual dysfunction in non-HIV settings is known to lead to poor adherence to prescribed medications, e.g. antihypertensive agents. Iatrogenic sexual dysfunction in patients may similarly have a potential to lead to poor antiretroviral compliance if not addressed.
Bell C, Richardson D, Wall M, et al., 2006, HIV-associated female sexual dysfunction - clinical experience and literature review., Int J STD AIDS, Vol: 17, Pages: 706-709, ISSN: 0956-4624
Women form an increasing proportion of HIV-infected individuals in the developed world. Early data suggest that women with HIV are at particular risk of developing sexual problems. The aim of this study was to describe our anecdotal experience of HIV-infected women and to ascertain their sexual dysfunction, and also to conduct a national survey to evaluate what sexual dysfunction services are provided for women in other UK HIV centres. Retrospective analysis of clinic notes of women attending our HIV clinic and letter surveys of HIV centres in the UK were carried out. About half our cohort reported that they had sexual problems or were not satisfied with sex over the preceding 12 months. Contextual issues seemed to be the commonest cause of these problems. Sixty percent of HIV physicians in the UK rarely/never ask their female HIV patients about sexual functioning. Sexual dysfunction is probably common in HIV-infected women. Most physicians seeing women with HIV in the UK do not ask about sexual functioning. 'Physician coaching' could help to redress this situation, so that at the least the sexual problems could be brought up in discussion.
Goldmeier D, Leiblum SR, 2006, Persistent genital arousal in women -- a new syndrome entity., Int J STD AIDS, Vol: 17, Pages: 215-216, ISSN: 0956-4624
The persistent sexual arousal syndrome (PSAS) is a newly described entity where women become involuntarily aroused genitally for extended periods in time in the absence of sexual desire. Genital vasoengorgement and oedema have been observed. These women are found to be usually very distressed. The cause of the syndrome in the majority of cases is unknown, although a number of women report symptoms after withdrawal from selective serotonin reuptake inhibitors (SSRI) antidepressants. There is no specific therapy at present, although electroconvulsive therapy (ECT) has resulted in clinical improvement in cases where there was concomitant severe depression.
Richardson D, Nalabanda A, Goldmeier D, 2006, Retarded ejaculation - a review., Int J STD AIDS, Vol: 17, Pages: 143-150, ISSN: 0956-4624
Retarded ejaculation, now termed the male orgasmic disorder is not only difficult to manage, but also the scientific evidence for aetiology, treatment and outcome is poor. This is compounded by incomplete consensus regarding definition from the scientific community. In this review, we intend to collate the available information on this sexual problem including definitions, possible aetiological factors and treatment options.
Richardson D, Wood K, Goldmeier D, 2006, A qualitative pilot study of islamic men with lifelong premature (rapid) ejaculation., J Sex Med, Vol: 3, Pages: 337-343, ISSN: 1743-6095
INTRODUCTION: Premature ejaculation is a common sexual problem in men. Although the etiology is unclear, there is emerging evidence that men from different ethnic backgrounds may be more at risk. AIM AND OBJECTIVE: The aim of this study was to generate themes and hypotheses around the etiology of premature ejaculation with particular reference to men from Islamic backgrounds. METHODS: This is an explorative qualitative study using semi-structured interviews with 10 male volunteers with a clinical diagnosis of premature ejaculation. Interviews were tape-recorded and transcribed. Transcriptions were then hand-coded and analyzed using grounded theory. RESULTS: Anxious first sexual experience (with subtheme: fear of being discovered and wanting to finish early); sex before marriage; sex outside of marriage; religion; "stress;" exposure to Western images; living in the United Kingdom; and the subsequent feeling of freedom were themes that emerged from the transcripts. CONCLUSIONS: We have identified factors associated with premature ejaculation in patients with Islamic backgrounds attending our unit. This may have useful therapeutic implications when consulting Islamic men with premature ejaculation.
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