Imperial College London
Alternate

ProfessorDavidHolden

Faculty of Medicine, Department of Infectious Disease

Professor
 
 
 
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Contact

 

+44 (0)20 7594 3073d.holden

 
 
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Location

 

221Flowers buildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

128 results found

Garvis S, Mei JM, Ruiz-Albert J, Holden DWet al., 2002, <i>Staphylococcus aureus svrA</i>:: a gene required for virulence and expression of the <i>agr</i> locus, MICROBIOLOGY-SGM, Vol: 148, Pages: 3235-3243, ISSN: 1350-0872

Journal article

Pawelek JM, Sodi S, Chakraborty AK, Platt JT, Miller S, Holden DW, Hensel M, Low KBet al., 2002, <i>Salmonella</i> pathogenicity island-2 and anticancer activity in mice, CANCER GENE THERAPY, Vol: 9, Pages: 813-818, ISSN: 0929-1903

Journal article

Brown JS, Holden DW, 2002, Iron acquisition by Gram-positive bacterial pathogens, MICROBES AND INFECTION, Vol: 4, Pages: 1149-1156, ISSN: 1286-4579

Journal article

Beuzón CR, Salcedo SP, Holden DW, 2002, Growth and killing of a <i>Salmonella enterica</i> serovar Typhimurium <i>sifA</i> mutant strain in the cytosol of different host cell lines, MICROBIOLOGY-SGM, Vol: 148, Pages: 2705-2715, ISSN: 1350-0872

Journal article

Yu XJ, Ruiz-Albert J, Unsworth KE, Garvis S, Liu M, Holden DWet al., 2002, SpiC is required for secretion of <i>Salmonella</i> Pathogenicity Island 2 type III secretion system proteins, CELLULAR MICROBIOLOGY, Vol: 4, Pages: 531-540, ISSN: 1462-5814

Journal article

Brown JS, Gilliland SM, Ruiz-Albert J, Holden DWet al., 2002, Characterization of pit, a <i>Streptococcus pneumoniae</i> iron uptake ABC transporter, INFECTION AND IMMUNITY, Vol: 70, Pages: 4389-4398, ISSN: 0019-9567

Journal article

Hindle Z, Chatfield SN, Phillimore J, Bentley M, Johnson J, Cosgrove CA, Ghaem-Maghami M, Sexton A, Khan M, Brennan FR, Everest P, Wu T, Pickard D, Holden DW, Dougan G, Griffin GE, House D, Santangelo JD, Khan SA, Shea JE, Feldman RG, Lewis DJAet al., 2002, Characterization of <i>Salmonella enterica</i> derivatives harboring defined <i>aroC</i> and <i>Salmonella</i> pathogenicity island 2 type III secretion system (<i>ssaV</i>) mutations by immunization of healthy volunteers, INFECTION AND IMMUNITY, Vol: 70, Pages: 3457-3467, ISSN: 0019-9567

Journal article

Ruiz-Albert J, Yu XJ, Beuzón CR, Blakey AN, Galyov EE, Holden DWet al., 2002, Complementary activities of SseJ and SifA regulate dynamics of the <i>Salmonella typhimurium</i> vacuolar membrane, MOLECULAR MICROBIOLOGY, Vol: 44, Pages: 645-661, ISSN: 0950-382X

Journal article

Holden DW, 2002, Trafficking of the <i>Salmonella</i> vacuole in macrophages, TRAFFIC, Vol: 3, Pages: 161-169, ISSN: 1398-9219

Journal article

, 2002, Identification of Genes

Patent

Brown JS, Ogunniyi AD, Gilliland SN, Woodrow MC, Holden DW, Paton JCet al., 2001, Immunisation with ABC transporter proteins protects against Streptococcus pneumoniae infection, THORAX, Vol: 56, Pages: 26-26, ISSN: 0040-6376

Journal article

Beuzón CR, Unsworth KE, Holden DW, 2001, In vivo genetic analysis indicates that PhoP-PhoQ and the <i>Salmonella</i> pathogenicity island 2 type III secretion system contribute independently to <i>Salmonella enterica</i> serovar typhimurium virulence, INFECTION AND IMMUNITY, Vol: 69, Pages: 7254-7261, ISSN: 0019-9567

Journal article

Beuzón CR, Holden DW, 2001, Use of mixed infections with <i>Salmonella</i> strains to study virulence genes and their interactions in vivo, MICROBES AND INFECTION, Vol: 3, Pages: 1345-1352, ISSN: 1286-4579

Journal article

Garvis SG, Beuzon CR, Holden DW, 2001, A role for the PhoP/Q regulon in inhibition of fusion between lysosomes and <i>Salmonella</i>-containing vacuoles in macrophages, CELLULAR MICROBIOLOGY, Vol: 3, Pages: 731-744, ISSN: 1462-5814

Journal article

Brown JS, Ogunniyi AD, Woodrow MC, Holden DW, Paton JCet al., 2001, Immunization with components of two iron uptake ABC transporters protects mice against systemic <i>Streptococcus</i> <i>pneumoniae</i> infection, INFECTION AND IMMUNITY, Vol: 69, Pages: 6702-6706, ISSN: 0019-9567

Journal article

, 2001, Identification of Genes

Patent

Webb JL, Harvey MW, Holden DW, Evans TJet al., 2001, Macrophage nitric oxide synthase associates with cortical actin but is not recruited to phagosomes, INFECTION AND IMMUNITY, Vol: 69, Pages: 6391-6400, ISSN: 0019-9567

Journal article

Salcedo SP, Noursadeghi M, Cohen J, Holden DWet al., 2001, Intracellular replication of <i>Salmonella typhimurium</i> strains in specific subsets of splenic macrophages <i>in vivo</i>, CELLULAR MICROBIOLOGY, Vol: 3, Pages: 587-597, ISSN: 1462-5814

Journal article

Méresse S, Unsworth KE, Habermann A, Griffiths G, Fang F, Martínez-Lorenzo MJ, Waterman SR, Gorvel JP, Holden DWet al., 2001, Remodelling of the actin cytoskeleton is essential for replication of intravacuolar <i>Salmonella</i>, CELLULAR MICROBIOLOGY, Vol: 3, Pages: 567-577, ISSN: 1462-5814

Journal article

Brown JS, Gilliland SM, Holden DW, 2001, A <i>Streptococcus pneumoniae</i> pathogenicity island encoding an ABC transporter involved in iron uptake and virulence, MOLECULAR MICROBIOLOGY, Vol: 40, Pages: 572-585, ISSN: 0950-382X

Journal article

Lau GW, Haataja S, Lonetto M, Kensit SE, Marra A, Bryant AP, McDevitt D, Morrison DA, Holden DWet al., 2001, A functional genomic analysis of type 3 <i>Streptococcus pneumoniae</i> virulence, MOLECULAR MICROBIOLOGY, Vol: 40, Pages: 555-571, ISSN: 0950-382X

Journal article

Yu J, Bryant AP, Marra A, Lonetto MA, Ingraham KA, Chalker AF, Holmes DJ, Holden D, Rosenberg M, McDevitt Det al., 2001, Characterization of the <i>Streptococcus pneumoniae</i> NADH oxidase that is required for infection, MICROBIOLOGY-UK, Vol: 147, Pages: 431-438, ISSN: 1350-0872

Journal article

, 2001, Identification of Genes

Patent

, 2000, Identification of Genes

Patent

, 2000, Identification of Genes

Patent

Beuzón CR, Méresse S, Unsworth KE, Ruíz-Albert J, Garvis S, Waterman SR, Ryder TA, Boucrot E, Holden DWet al., 2000, <i>Salmonella</i> maintains the integrity of its intracellular vacuole through the action of SifA, EMBO JOURNAL, Vol: 19, Pages: 3235-3249, ISSN: 0261-4189

Journal article

Brown JS, Aufauvre-Brown A, Brown J, Jennings JM, Arst H, Holden DWet al., 2000, Signature-tagged and directed mutagenesis identify PABA synthetase as essential for <i>Aspergillus fumigatus</i> pathogenicity, MOLECULAR MICROBIOLOGY, Vol: 36, Pages: 1371-1380, ISSN: 0950-382X

Journal article

Dorman CJ, Dougan G, Holden DW, Williams P, Smith Het al., 2000, The activities of bacterial pathogens <i>in vivo</i> -: Preface, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, Vol: 355, Pages: 549-550, ISSN: 0962-8436

Journal article

Unsworth KE, Holden DW, 2000, Identification and analysis of bacterial virulence genes <i>in vivo</i>, PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 355, Pages: 613-622, ISSN: 0962-8436

Journal article

Vazquez-Torres A, Xu YS, Jones-Carson J, Holden DW, Lucia SM, Dinauer MC, Mastroeni P, Fang FCet al., 2000, <i>Salmonella</i> pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase, SCIENCE, Vol: 287, Pages: 1655-1658, ISSN: 0036-8075

Journal article

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