Imperial College London
Alternate

Professor Deirdre Hollingsworth

Faculty of Medicine, School of Public Health

Honorary Lecturer
 
 
 
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Contact

 

d.hollingsworth Website

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Borlase:2020:10.1101/2020.10.27.20219618,
author = {Borlase, A and Blumberg, S and Callahan, EK and Deiner, MS and Nash, SD and Porco, TC and Solomon, AW and Lietman, TM and Prada, JM and Hollingsworth, TD},
doi = {10.1101/2020.10.27.20219618},
title = {Modelling trachoma post 2020: Opportunities for mitigating the impact of COVID-19 and accelerating progress towards elimination},
url = {http://dx.doi.org/10.1101/2020.10.27.20219618},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>The COVID-19 pandemic has disrupted planned annual antibiotic mass drug administration (MDA) activities which have formed the cornerstone of the largely successful global efforts to eliminate trachoma as a public health problem.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Using a mathematical model we investigate the impact of interruption to MDA in trachoma-endemic settings. We evaluate potential measures to mitigate this impact and consider alternative strategies for accelerating progress in those areas where the trachoma elimination targets may not be achievable otherwise.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>We demonstrate that for districts which were hyperendemic at baseline, or where the trachoma elimination thresholds have not already been achieved after 3 rounds of MDA, the interruption to planned MDA could lead to a delay greater than the duration of interruption. We also show that an additional round of MDA in the year following MDA resumption could effectively mitigate this delay. For districts where probability of elimination under annual MDA was already very low, we demonstrate that more intensive MDA schedules are needed to achieve agreed targets.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Through appropriate use of additional MDA, the impact of COVID-19 in terms of delay to reaching trachoma elimination targets can be effectively mitigated. Additionally, more frequent MDA may accelerate progress towards 2030 goals.</jats:p></jats:sec>
AU  - Borlase,A
AU  - Blumberg,S
AU  - Callahan,EK
AU  - Deiner,MS
AU  - Nash,SD
AU  - Porco,TC
AU  - Solomon,AW
AU  - Lietman,TM
AU  - Prada,JM
AU  - Hollingsworth,TD
DO  - 10.1101/2020.10.27.20219618
PY  - 2020///
TI  - Modelling trachoma post 2020: Opportunities for mitigating the impact of COVID-19 and accelerating progress towards elimination
UR  - http://dx.doi.org/10.1101/2020.10.27.20219618
ER  -
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