Imperial College London

ProfessorDebbieJarvis

Faculty of MedicineNational Heart & Lung Institute

Professor of Public Health
 
 
 
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Contact

 

+44 (0)20 7594 7944d.jarvis

 
 
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Assistant

 

Ms Hilary Barton +44 (0)20 7594 7942

 
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Location

 

28Emmanuel Kaye BuildingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

343 results found

Svanes C, Heinrich J, Jarvis D, Chinn S, Omenaas E, Gulsvik A, Künzli N, Burney Pet al., 2003, Pet-keeping in childhood and adult asthma and hay fever:: European Community Respiratory Health Survey, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 112, Pages: 289-300, ISSN: 0091-6749

Journal article

Harvey S, Forbes L, Jarvis D, Price J, Burney Pet al., 2003, Accident and emergency departments are still failing to assess asthma severity, EMERGENCY MEDICINE JOURNAL, Vol: 20, Pages: 329-331, ISSN: 1472-0205

Journal article

Knox J, Jarvis D, 2003, The European Community Respiratory Health Survey II, EUROPEAN RESPIRATORY JOURNAL, Vol: 21, Pages: 556-556, ISSN: 0903-1936

Journal article

Forbes L, Jarvis D, Potts J, Baxter PJet al., 2003, Volcanic ash and respiratory symptoms in children on the island of Montserrat, British West Indies, OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, Vol: 60, Pages: 207-211, ISSN: 1351-0711

Journal article

Chinn S, Jarvis D, Burney P, European Community Respiratory Health Surveyet al., 2002, Relation of bronchial responsiveness to body mass index in the ECRHS. European Community Respiratory Health Survey., Thorax, Vol: 57, Pages: 1028-1033, ISSN: 0040-6376

BACKGROUND: There is substantial evidence for an association between symptoms of asthma and overweight or obesity. However, a study that reported no association between bronchial responsiveness (BHR) and body mass index (BMI) suggested that the relation of symptoms to obesity was due to increased diagnosis of asthma. The relation of BHR to BMI was therefore investigated in a large multicentre study. METHODS: Data were obtained for 11,277 participants in stage II of the European Community Respiratory Health Survey (ECRHS). BHR to methacholine was analysed in relation to BMI adjusted for a number of factors known to be associated with BHR, including baseline lung function and allergen sensitisation, and combined across 34 centres using random effects meta-analysis. RESULTS: BHR increased with increasing BMI in men (ECRHS slope changed by -0.027 for each unit increase in BMI, 95% confidence interval -0.044 to -0.010, p=0.002), but the relation in women was weak (-0.014, 95% CI -0.033 to 0.005, p=0.14). There was no evidence for an interaction of sex with BMI (p=0.41). CONCLUSIONS: BHR is related to BMI in the ECRHS. This suggests that the association is not due to greater diagnosis or perception of symptoms in obese people compared with those of normal weight. The data do not support the finding by some studies of a relation between asthma and obesity in women but not in men.

Journal article

Chinn S, Jarvis D, Burney P, 2002, Relation of bronchial responsiveness to body mass index in the ECRHS, THORAX, Vol: 57, Pages: 1028-1033, ISSN: 0040-6376

Journal article

Jarvis D, 2002, The European Community Respiratory Health Survey II, EUROPEAN RESPIRATORY JOURNAL, Vol: 20, Pages: 1071-1079, ISSN: 0903-1936

Journal article

Svanes C, Jarvis D, Chinn S, Omenaas E, Gulsvik A, Burney Pet al., 2002, Early exposure to children in family and day care as related to adult asthma and hay fever: results from the European Community Respiratory Health Survey, THORAX, Vol: 57, Pages: 945-950, ISSN: 0040-6376

Journal article

Zock JP, Kogevinas M, Sunyer J, Jarvis D, Torén K, Antó JMet al., 2002, Asthma characteristics in cleaning workers, workers in other risk jobs and office workers, EUROPEAN RESPIRATORY JOURNAL, Vol: 20, Pages: 679-685, ISSN: 0903-1936

Journal article

Zock JP, Jarvis D, Luczynska C, Sunyer J, Burney Pet al., 2002, Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 110, Pages: 285-292, ISSN: 0091-6749

Journal article

Jarvis D, Chinn S, Potts J, Burney Pet al., 2002, Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey, CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 32, Pages: 831-837, ISSN: 0954-7894

Journal article

Janson C, Chinn S, Jarvis D, Zock JP, Torén K, Burney Pet al., 2001, Effect of passive smoking on respiratory symptoms, bronchial responsiveness, lung function, and total serum IgE in the European Community Respiratory Health Survey:: a cross-sectional study, LANCET, Vol: 358, Pages: 2103-2109, ISSN: 0140-6736

Journal article

Leynaert B, Neukirch C, Jarvis D, Chinn S, Burney P, Neukirch Fet al., 2001, Does living on a farm during childhood protect against asthma, allergic rhinitis, and atopy in adulthood?, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 164, Pages: 1829-1834, ISSN: 1073-449X

Journal article

Janson C, Chinn S, Jarvis D, Burney Pet al., 2001, Determinants of cough in young adults participating in the European Community Respiratory Health Survey, EUROPEAN RESPIRATORY JOURNAL, Vol: 18, Pages: 647-654, ISSN: 0903-1936

Journal article

Janson C, Anto J, Burney P, Chinn S, de Marco R, Heinrich J, Jarvis D, Kuenzli N, Leynaert B, Luczynska C, Neukirch F, Svanes C, Sunyer J, Wjst Met al., 2001, The European Community Respiratory Health Survey: what are the main results so far?, EUROPEAN RESPIRATORY JOURNAL, Vol: 18, Pages: 598-611, ISSN: 0903-1936

Journal article

Forbes L, Jarvis D, Bumey P, 2000, Is pre-menstrual asthma related to use of aspirin or non-steroidal anti-inflammatory drugs?, RESPIRATORY MEDICINE, Vol: 94, Pages: 828-829, ISSN: 0954-6111

Journal article

Till SJ, Durham SR, 2000, Asthma & Rhinitis, Publisher: Blackwell Science Ltd, ISBN: 9780632041756

Book

Jarvis D, 1999, Gas cooking and respiratory disease, THORAX, Vol: 54, Pages: 1054-1054, ISSN: 0040-6376

Journal article

Jarvis D, Chinn S, Luczynska C, Burney Pet al., 1999, The association of smoking with sensitization to common environmental allergens: Results from the European Community Respiratory Health Survey, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 104, Pages: 934-940, ISSN: 0091-6749

Journal article

Roost HP, Künzli N, Schindler C, Jarvis D, Chinn S, Perruchoud AP, Ackermann-Liebrich U, Burney P, Wüthrich Bet al., 1999, Role of current and childhood exposure to cat and atopic sensitization, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 104, Pages: 941-947, ISSN: 0091-6749

Journal article

Forbes L, Jarvis D, Burney P, 1999, Do hormonal contraceptives influence asthma severity?, EUROPEAN RESPIRATORY JOURNAL, Vol: 14, Pages: 1028-1033, ISSN: 0903-1936

Journal article

Roost HP, Künzli N, Schindler C, Jarvis D, Chinn S, Perruchoud AP, Ackermann-Liebrich U, Burney P, Wüthrich Bet al., 1999, Role of current and childhood exposure to cat and atopic sensitization. European Community Respiratory Health Survey., J Allergy Clin Immunol, Vol: 104, Pages: 941-947, ISSN: 0091-6749

BACKGROUND: Clinical and population studies have shown that exposure and sensitization to allergens derived from furred pets, particularly cats, represent an important risk factor of allergic respiratory disease and also a significant risk factor for asthma. OBJECTIVE: In the framework of the multicenter European Community Respiratory Health Survey an analysis of the association of current and childhood exposure to cat with atopic sensitization to cat was conducted. METHODS: This study included cross-sectional data from 35 centers representing 16 countries. Altogether, 18,097 subjects were included, of whom 13,509 (75%) provided a blood sample for the measurement of specific IgE. Exposure data and data for potential confounders were extracted from an interviewer-led questionnaire. RESULTS: The prevalence of sensitization to cat (serum specific IgE >0.35 kU/L) was 9%. Among those who did not report allergic symptoms in the presence of pets or house dust, those who owned cats were significantly more likely to be sensitized to cats than were those who did not (odds ratio [95% confidence interval] 1.57 [1.20-2.06]. Childhood exposure to pets including cats was associated with lower sensitization to cats in adulthood, particularly among those with a positive family history of atopy (odds ratio [95% confidence interval] 0.68 [0.51-0.93]. Positive correlations were found between the community prevalence of cat and the prevalences of sensitization to cat, respiratory symptoms, physician-diagnosed asthma, and current asthma medication. CONCLUSIONS: Current cat ownership represents a significant risk for sensitization to cat if cats are allowed indoors. Our results support the hypothesis that childhood exposure to pets, including cats, might modulate immunologic mechanisms and reduce sensitization to cat in adulthood. The significant correlation found between the community prevalence of cat ownership and community prevalence of specific sensitization to cat represents the

Journal article

Chinn S, Burney P, Sunyer J, Jarvis D, Luczynska Cet al., 1999, Sensitization to individual allergens and bronchial responsiveness in the ECRHS. European Community Respiratory Health Survey., Eur Respir J, Vol: 14, Pages: 876-884, ISSN: 0903-1936

Little is known about the relation of bronchial responsiveness (BHR) to sensitization to individual allergens, or its variation between countries. Data were obtained for BHR, specific immunoglobulin E and confounding variables from 11,215 subjects, aged 20-44 yrs at the start of the European Community Respiratory Health Survey, in 34 centres in 15 countries. The relation of BHR to sensitization to cat, house dust mite, timothy grass and Cladosporium was estimated by means of multiple regression for each centre, and combined across centres by random effects meta-analysis, controlling for baseline lung function, height, sex, season of testing, age, smoking and age/sex and age/smoking interactions. BHR was greater, on average, in those sensitized to cat (p=0.023), house dust mite (p<0.001) and timothy grass (p=0.018), but not to Cladosporium (p=0.60), and increased with degree of sensitization (p<0.001). All relations showed heterogeneity between centres, although to a lesser extent in the relation to sensitization to house dust mite. More variation in bronchial responsiveness was explained by sensitization and degree of sensitization to the individual allergens than by atopy defined as any positive test in each centre, but the relative importance of each allergen varied. The use of atopy as a single variable in relation to bronchial hyperresponsiveness may be misleading.

Journal article

Chinn S, Burney P, Sunyer J, Jarvis D, Luczynska Cet al., 1999, Sensitization to individual allergens and bronchial responsiveness in the ECRHS, EUROPEAN RESPIRATORY JOURNAL, Vol: 14, Pages: 876-884, ISSN: 0903-1936

Journal article

Svanes C, Jarvis D, Chinn S, Burney Pet al., 1999, Childhood environment and adult atopy: Results from the European Community Respiratory Health Survey, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol: 103, Pages: 415-420, ISSN: 0091-6749

Journal article

Janson C, Chinn S, Jarvis D, Burney Pet al., 1998, Individual use of antiasthmatic drugs in the European Community Respiratory Health Survey, EUROPEAN RESPIRATORY JOURNAL, Vol: 12, Pages: 557-563, ISSN: 0903-1936

Journal article

Chinn S, Jarvis D, Luczynska C, Burney Pet al., 1998, Individual allergens as risk factors for bronchial responsiveness in young adults, THORAX, Vol: 53, Pages: 662-667, ISSN: 0040-6376

Journal article

Jarvis D, Chinn S, Sterne J, Luczynska C, Burney Pet al., 1998, The association of respiratory symptoms and lung function with the use of gas for cooking. European Community Respiratory Health Survey., Eur Respir J, Vol: 11, Pages: 651-658, ISSN: 0903-1936

The association of respiratory symptoms and lung function with the use of gas for cooking was examined using data collected as part of the European Community Respiratory Health Survey, an international multicentre study. Associations between gas cooking and respiratory symptoms and respiratory function were assessed by logistic and multiple regression models. Tests for interaction were used to examine whether the effect of gas cooking varied between centres and, as there was evidence for this, the average effects were estimated using standard methods for random effects meta-analysis. Data from 5,561 males and 6,029 females living in 23 centres in 11 countries were analysed. There was no significant association found between respiratory symptoms and gas cooking in males. In females the association between some respiratory symptoms and gas cooking varied between centres with an overall positive association with "wheeze in the last 12 months" (odds ratio (OR) 1.24: 95% confidence interval (95% CI) 1.00-1.54) and "wheeze with breathlessness in the last 12 months" (OR 1.33: 95% CI 1.06-1.69). There was no evidence that atopy modified this association. Cooking with gas was associated with airways obstruction in both males and females although the differences failed to reach statistical significance. In some countries the use of gas for cooking is associated with respiratory symptoms suggestive of airways obstruction in females.

Journal article

Jarvis D, Chinn S, Sterne J, Luczynska C, Burney Pet al., 1998, The association of respiratory symptoms and lung function with the use of gas for cooking, EUROPEAN RESPIRATORY JOURNAL, Vol: 11, Pages: 651-658, ISSN: 0903-1936

Journal article

Jarvis D, Burney P, 1998, ABC of allergies - The epidemiology of allergic disease, BRITISH MEDICAL JOURNAL, Vol: 316, Pages: 607-610, ISSN: 0959-8138

Journal article

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