Imperial College London


Faculty of Natural SciencesDepartment of Chemistry




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Molecular Sciences Research HubWhite City Campus





David Klug joined the Department of Chemistry in October 1998, having from October 1995 held a joint position in the Departments of Biochemistry and Chemistry.  From October 1990 to September 1995 he was a Royal Society University Research Fellow jointly in Biochemistry and Chemistry.  He graduated in Physics at University College London in 1984, and obtained his Ph.D. at The Royal Institution in 1987.

David is co-founder of the Institute of Chemical Biology  ( ), which co-ordinates teaching and research activities in Chemical Biology. He also chaired the Single Cell Proteomics Project, a £5 million multidisciplinary collaboration of eight research teams developing and applying novel platform technologies to high throughput and single cell analysis ( and the Proxomics Project, platform technologies for the analysis of oxidative damage to proteins ( More information about David's research group can be found at .






Sowley H, Liu Z, Davies J, et al., 2019, Detection of drug binding to a target protein using EVV 2DIR spectroscopy, Journal of Physical Chemistry B, Vol:123, ISSN:1520-5207, Pages:3598-3606

Lakatos E, Salehi-Reyhani S, Barclay M, et al., 2017, Protein degradation rate is the dominant mechanism accounting for the differences in protein abundance of basal p53 in a human breast and colorectal cancer cell line, Plos One, Vol:12, ISSN:1932-6203

Magness AJ, Squires J, Griffiths B, et al., 2017, Multiplexed single cell protein expression analysis in solid tumours using a miniaturised microfluidic assay, Convergent Science Physical Oncology, Vol:3, ISSN:2057-1739


Tahirbegi B, Magness AJ, Boillat A, et al., 2018, Probing synaptic amyloid-beta aggregation promoted by copper release, 62nd Annual Meeting of the Biophysical-Society, Biophysical Society, Pages:430A-430A, ISSN:0006-3495

Sim S, Sowley H, Kidley N, et al., 2017, Investigation of inhibitor-protein interactions in plants & mammalians from EVV 2DIR data, 254th National Meeting and Exposition of the American-Chemical-Society (ACS) on Chemistry's Impact on the Global Economy, AMER CHEMICAL SOC, ISSN:0065-7727

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