Imperial College London
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Mr Daniel Richard Leff

Faculty of Medicine, Department of Surgery & Cancer

Reader in Breast Surgery
 
 
 
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Contact

 

d.leff Website

 
 
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Location

 

016Paterson WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Jiwa:2021:10.1136/bmjnph-2021-000266,
author = {Jiwa, N and Takats, Z and Leff, D},
doi = {10.1136/bmjnph-2021-000266},
journal = {BMJ Nutrition, Prevention & Health},
pages = {1--7},
title = {Breast health screening: a UK-wide questionnaire},
url = {http://dx.doi.org/10.1136/bmjnph-2021-000266},
volume = {4},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background Currently, there is an unmet clinical need in identifying and screening women at high risk of breast cancer, where tumours are often aggressive and treatment intervention is too late to prevent metastasis, recurrence and mortality. This has been brought into sharp focus by the SARS-CoV-2 global pandemic, constantly changing hospital policies and surgical guidelines in reducing access to established screening and treatment regimens. Nipple aspirate fluid (NAF), is thought to provide a unique window into the biological processes occurring within the breast, particularly in the context of a developing neoplasm. Evaluation of NAF in asymptomatic women, for novel chemical biomarkers of either early disease and/or cancer risk offers tremendous promise as a tool to facilitate early detection and to supplement screening. However, it is acceptability as a method of collection and screening by women is critical and yet unknown. A breast health questionnaire was disseminated to women through breast cancer charities, patient support groups and social media platforms, with the aim of collecting opinions on the acceptability of use of NAF as a potential screening tool.Method Following ethical approval a questionnaire was prepared using online surveys consisting of four parts: (a) introduction on breast health screening in the UK, (b) core demographic data, (c) questions regarding screening and the acceptability of using NAF and (d) opinions about the process of collecting and using nipple fluid for screening. The voluntary and anonymous questionnaire was disseminated through social media, professional networks, charity websites and by individuals between October 2019 and December 2020. Survey responses were collected electronically, and the data analysed using online surveys statistical tools.Results A total of 3178 women completed the questionnaire (65.9% Caucasian, 27.7% Asian/British Asian, 0.6% black and 5.0% other). Of these, 2650 women (83.4%) had no prior knowle
AU  - Jiwa,N
AU  - Takats,Z
AU  - Leff,D
DO  - 10.1136/bmjnph-2021-000266
EP  - 7
PY  - 2021///
SN  - 2516-5542
SP  - 1
TI  - Breast health screening: a UK-wide questionnaire
T2  - BMJ Nutrition, Prevention & Health
UR  - http://dx.doi.org/10.1136/bmjnph-2021-000266
UR  - https://nutrition.bmj.com/content/early/2021/05/04/bmjnph-2021-000266
UR  - http://hdl.handle.net/10044/1/89251
VL  - 4
ER  -
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