Imperial College London
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Mr Daniel Richard Leff

Faculty of Medicine, Department of Surgery & Cancer

Reader in Breast Surgery
 
 
 
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Contact

 

d.leff Website

 
 
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Location

 

016Paterson WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Jiwa:2022:10.1016/j.amsu.2022.103625,
author = {Jiwa, N and Ezzat, A and holt, J and wijayatilake, D and Takats, Z and Leff, D},
doi = {10.1016/j.amsu.2022.103625},
journal = {Annals of Medicine and Surgery},
pages = {1--6},
title = {Nipple aspirate fluid and its use for the early detection of breast cancer},
url = {http://dx.doi.org/10.1016/j.amsu.2022.103625},
volume = {77},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Nipple aspirate fluid is the physiological biofluid lining ductal epithelial cells. Historically, cytology of nipple fluid has been the gold standard diagnostic method for assessment of ductal fluid in patients with symptomatic nipple discharge. The role of biomarker discovery in nipple aspirate fluid for assessment of asymptomatic and high-risk patients is highly attractive but evaluation to date is limited by poor diagnostic accuracy. However, the emergence of new technologies capable of identifying metabolites that have been previously thought unidentifiable within such small volumes of fluid, has enabled testing of nipple biofluid to be re-examined. This review evaluates the use of new technologies to evaluate the components of nipple fluid and their potential to serve as biomarkers in screening.
AU  - Jiwa,N
AU  - Ezzat,A
AU  - holt,J
AU  - wijayatilake,D
AU  - Takats,Z
AU  - Leff,D
DO  - 10.1016/j.amsu.2022.103625
EP  - 6
PY  - 2022///
SN  - 2049-0801
SP  - 1
TI  - Nipple aspirate fluid and its use for the early detection of breast cancer
T2  - Annals of Medicine and Surgery
UR  - http://dx.doi.org/10.1016/j.amsu.2022.103625
UR  - https://www.sciencedirect.com/science/article/pii/S2049080122003855
UR  - http://hdl.handle.net/10044/1/96830
VL  - 77
ER  -
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