Imperial College London

Professor David MacIntyre

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Professor in Reproduction Systems Medicine
 
 
 
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Contact

 

+44 (0)20 7594 2195d.macintyre Website

 
 
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Location

 

Institute of Reproductive and Developmental BiologyHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{MacIntyre:2020,
author = {MacIntyre, D and Beagley, K},
booktitle = {Principles of Mucosal Immunology},
publisher = {Garland Science},
title = {The immune system of the genitourinary tract},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - CHAP
AB - The human genitourinary tract is characterized by a complex system of compartmentalized, highly integrated tissues, finely tuned hormonal regulation, and an immune system that has some similarities to, but also distinct differences from, the gastrointestinal immune system. Innate and adaptive immune defenses in the genitourinary tract influence, and are influenced by, the composition of commensal microbial communities, which provide a degree of protection against sexually transmitted diseases. The mucosal immune system in the female reproductive tract contains an array of protective mechanisms that are under hormonal control. Immune cell organization varies with tissue and stage of the menstrual cycle. Sex hormones also regulate immune-cell function in tissues of the female reproductive tract as the immune system faces the unique challenge of protecting tissues that are changing shape, thickness, and vascularity. The mucosal immune system in the male and female human reproductive tracts has evolved to meet the unique requirements of procreation and host defense against genital tract pathogens.
AU - MacIntyre,D
AU - Beagley,K
PB - Garland Science
PY - 2020///
SN - 9781000754490
TI - The immune system of the genitourinary tract
T1 - Principles of Mucosal Immunology
ER -