Imperial College London

Diego A. Oyarzún

Faculty of Natural SciencesDepartment of Mathematics

Honorary Lecturer



d.oyarzun Website




6M48Huxley BuildingSouth Kensington Campus





Diego is Reader in Computational Biology at The University of Edinburgh, where he holds a joint appointment at the School of Informatics and the School of Biological Sciences.

In 2016 Diego was appointed Global Future Council Fellow by the World Economic Forum to serve in the Council on Biotechnologies. In 2017 he was selected as one of the 100 Young Global Changers by the Think 20 Summit and the G20 presidency. Diego also serves in the Scientific Advisory Board for the WEF Center for the Fourth Industrial Revolution in San Francisco and the EPSRC Early Career Forum in Mathematical Sciences. He is an Associate Editor for the journals Frontiers in Synthetic Biology and Microbial Cell Factories.

Diego is part of programme committees of several international conferences and referee for over 20 scientific journals. He also has a number of relevant roles at Edinburgh:

More information in his research website at The University of Edinburgh.

Selected Publications

Journal Articles

O'Day E, Hosta-Rigau L, Oyarzún DA, et al., 2019, Are we there yet? How and when specific biotechnologies will improve human health, Biotechnology Journal, Vol:14, ISSN:1860-6768

Beguerisse M, Bosque G, Oyarzun DA, et al., 2018, Flux-dependent graphs for metabolic networks, Npj Systems Biology and Applications, Vol:4, ISSN:2056-7189

de Lorenzo V, Prather KL, Chen G-Q, et al., 2018, The power of synthetic biology for bioproduction, remediation and pollution control, EMBO Reports, Vol:19, ISSN:1469-221X

Mannan AA, Liu D, Zhang F, et al., 2017, Fundamental design principles for transcription-factor-based metabolite biosensors, Acs Synthetic Biology, Vol:6, ISSN:2161-5063, Pages:1851-1859

Sootla A, Oyarzun DA, Angeli D, et al., 2016, Shaping Pulses to Control Bistable Systems: Analysis, Computation and Counterexamples, Automatica, Vol:63, ISSN:1873-2836, Pages:254-264

Oyarzun DA, Chaves M, 2015, Design of a bistable switch to control cellular uptake, Journal of the Royal Society Interface, Vol:20150618, ISSN:1742-5689

Weisse AY, Oyarzun DA, Danos V, et al., 2015, Mechanistic links between cellular trade-offs, gene expression, and growth, Proceedings of the National Academy of Sciences of the United States of America, Vol:112, ISSN:0027-8424, Pages:E1038-E1047

Waldherr S, Oyarzun DA, Bockmayr A, 2014, Dynamic optimization of metabolic networks coupled with gene expression, Journal of Theoretical Biology, Vol:365, ISSN:1095-8541, Pages:469-485

Oyarzun DA, Lugagne J-B, Stan G-B, 2014, Noise propagation in synthetic gene circuits for metabolic control, Acs Synthetic Biology, Vol:4, ISSN:2161-5063, Pages:116-125

Oyarzun DA, Chaves M, Hoff-Hoffmeyer-Zlotnik M, 2012, Multistability and oscillations in genetic control of metabolism, Journal of Theoretical Biology, Vol:295, ISSN:0022-5193, Pages:139-153

Oyarzún DA, Stan GB, 2012, Synthetic gene circuits for metabolic control: design tradeoffs and constraints, Journal of the Royal Society Interface, Vol:10

Oyarzun DA, Ingalls BP, Middleton RH, et al., 2009, Sequential Activation of Metabolic Pathways: a Dynamic Optimization Approach, Bulletin of Mathematical Biology, Vol:71, ISSN:0092-8240, Pages:1851-1872

More Publications