Publications

BibTex format

@article{Ng:2023:ehjopen/oead021,
author = {Ng, M-Y and Kwan, CT and Yap, PM and Fung, SY and Tang, HS and Tse, WWV and Kwan, CNF and Chow, YHP and Yiu, NC and Lee, YP and Fong, AHT and Hwang, S and Fong, ZFW and Ren, Q-W and Wu, M-Z and Wan, EYF and Lee, KCK and Leung, CY and Li, A and Montero, D and Vardhanabhuti, V and Hai, J and Siu, C-W and Tse, H-F and Pennell, DJ and Mohiaddin, R and Senior, R and Yiu, K-H},
doi = {ehjopen/oead021},
journal = {Eur Heart J Open},
title = {Diagnostic accuracy of cardiovascular magnetic resonance strain analysis and atrial size to identify heart failure with preserved ejection fraction.},
url = {http://dx.doi.org/10.1093/ehjopen/oead021},
volume = {3},
year = {2023}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - AIMS: Heart failure with preserved ejection fraction (HFpEF) continues to be a diagnostic challenge. Cardiac magnetic resonance atrial measurement, feature tracking (CMR-FT), tagging has long been suggested to diagnose HFpEF and potentially complement echocardiography especially when echocardiography is indeterminate. Data supporting the use of CMR atrial measurements, CMR-FT or tagging, are absent. Our aim is to conduct a prospective case-control study assessing the diagnostic accuracy of CMR atrial volume/area, CMR-FT, and tagging to diagnose HFpEF amongst patients suspected of having HFpEF. METHODS AND RESULTS: One hundred and twenty-one suspected HFpEF patients were prospectively recruited from four centres. Patients underwent echocardiography, CMR, and N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurements within 24h to diagnose HFpEF. Patients without HFpEF diagnosis underwent catheter pressure measurements or stress echocardiography to confirm HFpEF or non-HFpEF. Area under the curve (AUC) was determined by comparing HFpEF with non-HFpEF patients. Fifty-three HFpEF (median age 78 years, interquartile range 74-82 years) and thirty-eight non-HFpEF (median age 70 years, interquartile range 64-76 years) were recruited. Cardiac magnetic resonance left atrial (LA) reservoir strain (ResS), LA area index (LAAi), and LA volume index (LAVi) had the highest diagnostic accuracy (AUCs 0.803, 0.815, and 0.776, respectively). Left atrial ResS, LAAi, and LAVi had significantly better diagnostic accuracy than CMR-FT left ventricle (LV)/right ventricle (RV) parameters and tagging (P < 0.01). Tagging circumferential and radial strain had poor diagnostic accuracy (AUC 0.644 and 0.541, respectively). CONCLUSION: Cardiac magnetic resonance LA ResS, LAAi, and LAVi have the highest diagnostic accuracy to identify HFpEF patients from non-HFpEF patients amongst clinically suspected HFpEF patients. Cardiac magnetic resonance feature tracking LV/RV parameters and tagging
AU  - Ng,M-Y
AU  - Kwan,CT
AU  - Yap,PM
AU  - Fung,SY
AU  - Tang,HS
AU  - Tse,WWV
AU  - Kwan,CNF
AU  - Chow,YHP
AU  - Yiu,NC
AU  - Lee,YP
AU  - Fong,AHT
AU  - Hwang,S
AU  - Fong,ZFW
AU  - Ren,Q-W
AU  - Wu,M-Z
AU  - Wan,EYF
AU  - Lee,KCK
AU  - Leung,CY
AU  - Li,A
AU  - Montero,D
AU  - Vardhanabhuti,V
AU  - Hai,J
AU  - Siu,C-W
AU  - Tse,H-F
AU  - Pennell,DJ
AU  - Mohiaddin,R
AU  - Senior,R
AU  - Yiu,K-H
DO  - ehjopen/oead021
PY  - 2023///
TI  - Diagnostic accuracy of cardiovascular magnetic resonance strain analysis and atrial size to identify heart failure with preserved ejection fraction.
T2  - Eur Heart J Open
UR  - http://dx.doi.org/10.1093/ehjopen/oead021
UR  - https://www.ncbi.nlm.nih.gov/pubmed/36992915
VL  - 3
ER  -

Download

ProfessorDudleyPennell

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)