Publications
235 results found
Phillips D, 2017, Postscript to the special issue commemorating Volume 100 of <i>Science Progress</i>, SCIENCE PROGRESS, Vol: 100, Pages: 438-440, ISSN: 0036-8504
Phillips D, 2017, Foreword to the special issue commemorating Volume 100 of Science Progress, SCIENCE PROGRESS, Vol: 100, Pages: 1-4, ISSN: 0036-8504
Phillips D, 2017, Ahmed zewail - an inspired and inspirational scientist and man, Personal And Scientific Reminiscences: Tributes To Ahmed Zewail, Pages: 221-228, ISBN: 9781786344366
In 1986, Sir John Meurig Thomas took up his position as Director of the Royal Institution of Great Britain (Ri), with me as Deputy Director. John liked to keep abreast of advances in all spheres of chemistry, and early in our joint time at the Ri, asked me who in the world best understood the concept of coherence. There was no doubt in my mind that this was Ahmed Zewail, who had published much on observed quantum interference effects in, for example, sodium iodide dissociation and reformation, but who was also exploring with Peter Felker the phenomenon of rotational coherences. I brought Ahmed’s work to John’s attention, and the rest is history, since a deep friendship developed between the two, which is outlined in the submission in this volume by Sir John….
Phillips D, 2016, A lifetime in photochemistry; some ultrafast measurements on singlet states, Proceedings of the Royal Society A: Mathematical, Physical & Engineering Sciences, Vol: 472, ISSN: 1471-2946
Phillips D, 2015, Healthy, wealthy and wise: the benefits of chemical research, SCIENCE PROGRESS, Vol: 98, Pages: 128-144, ISSN: 0036-8504
French PMW, 2014, Fluorescence Lifetime Imaging for Biomedicine, 2014 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO), ISSN: 2160-9020
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- Citations: 1
Phillips D, 2011, Little light relief: A synopsis, 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Publisher: AMER CHEMICAL SOC, ISSN: 0065-7727
Phillips D, 2011, Whither university chemistry?, Education in Chemistry, Vol: 48, ISSN: 0013-1350
Phillips D, 2011, Physics in a chemist's world, PHYSICS WORLD, Vol: 24, Pages: 16-17, ISSN: 0953-8585
Phillips D, 2011, Toward targeted photodynamic therapy, PURE AND APPLIED CHEMISTRY, Vol: 83, Pages: 733-748, ISSN: 0033-4545
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- Citations: 31
Phillips D, 2010, Light relief: photochemistry and medicine, PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, Vol: 9, Pages: 1589-1596, ISSN: 1474-905X
Levitt JA, Kuimova MK, Yahioglu G, et al., 2010, Fluorescence lifetime imaging of molecular rotors to map microviscosity in cells, CHINESE OPTICS LETTERS, Vol: 8, Pages: 926-930, ISSN: 1671-7694
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- Citations: 3
Stamati I, Kuimova MK, Lion M, et al., 2010, Novel photosensitisers derived from pyropheophorbide-a: uptake by cells and photodynamic efficiency in vitro, PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, Vol: 9, Pages: 1033-1041, ISSN: 1474-905X
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- Citations: 30
Levitt JA, Kuimova MK, Yahioglu G, et al., 2009, Membrane-Bound Molecular Rotors Measure Viscosity in Live Cells via Fluorescence Lifetime Imaging, JOURNAL OF PHYSICAL CHEMISTRY C, Vol: 113, Pages: 11634-11642, ISSN: 1932-7447
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- Citations: 179
Stamati I, Phillips D, Yahioglu G, et al., 2009, Targeted photodynamic therapy of cancer using novel photosensitizer derivatives based on pyropheophorbide-a (PPa), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol: 237, ISSN: 0065-7727
Dahlstedt E, Collins HA, Balaz M, et al., 2009, One- and two-photon activated phototoxicity of conjugated porphyrin dimers with high two-photon absorption cross sections, ORGANIC & BIOMOLECULAR CHEMISTRY, Vol: 7, Pages: 897-904, ISSN: 1477-0520
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- Citations: 85
Kuimova MK, Collins HA, Balaz M, et al., 2009, Photophysical properties and intracellular imaging of water-soluble porphyrin dimers for two-photon excited photodynamic therapy, ORGANIC & BIOMOLECULAR CHEMISTRY, Vol: 7, Pages: 889-896, ISSN: 1477-0520
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- Citations: 125
Collins HA, Khurana M, Moriyama EH, et al., 2008, Blood-vessel closure using photosensitizers engineered for two-photon excitation, NATURE PHOTONICS, Vol: 2, Pages: 420-424, ISSN: 1749-4885
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- Citations: 324
Yau CMS, Pascu SI, Odom SA, et al., 2008, Stabilisation of a heptamethine cyanine dye by rotaxane encapsulation, CHEMICAL COMMUNICATIONS, Pages: 2897-2899, ISSN: 1359-7345
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- Citations: 72
Kwok WM, Ma C, George MW, et al., 2007, Solvent effects on the charge transfer excited states of 4-dimethylaminobenzonitrile (DMABN) and 4-dimethylamino-3,5-dimethylbenzonitrile (TMABN) studied by time-resolved infrared spectroscopy: a direct observation of hydrogen bonding interactions, PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, Vol: 6, Pages: 987-994, ISSN: 1474-905X
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- Citations: 28
Balaz M, Collins HA, Kuimova MK, et al., 2007, MEDI 272-Two-photon excited photodynamic therapy using water-soluble porphyrin dimers, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol: 234, ISSN: 0065-7727
Balaz M, Collins HA, Kuimova MK, et al., 2007, MEDI 118-Conjugated porphyrin dimers with large two-photon absorption cross section for photodynamic therapy, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, Vol: 234, ISSN: 0065-7727
Kuimova MK, Bhatti M, Deonarain M, et al., 2007, Fluorescence characterisation of multiply-loaded anti-HER2 single chain Fv-photosesitizer conjugates suitable for photodynamic therapy, Photochemical Photobiological Sciences, Vol: 6, Pages: 933-939
Kuimova MK, Hoffmann M, Winters MU, et al., 2007, Determination of the triplet state energies of a series of conjugated porphyrin oligomers, PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, Vol: 6, Pages: 675-682, ISSN: 1474-905X
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- Citations: 39
Boens N, Qin W, Basaric N, et al., 2007, Fluorescence lifetime standards for time and frequency domain fluorescence spectroscopy, ANALYTICAL CHEMISTRY, Vol: 79, Pages: 2137-2149, ISSN: 0003-2700
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- Citations: 350
Treanor B, Lanigan PMP, Kumar S, et al., 2006, Microclusters of inhibitory killer immunoglobulin like receptor signaling at natural killer cell immunological synapses, Journal of Cell Biology, Vol: 174, Pages: 153-161, ISSN: 1540-8140
We report the supramolecular organization of killer Ig–like receptor (KIR) phosphorylation using a technique applicable to imaging phosphorylation of any green fluorescent protein–tagged receptor at an intercellular contact or immune synapse. Specifically, we use fluorescence lifetime imaging (FLIM) to report Förster resonance energy transfer (FRET) between GFP-tagged KIR2DL1 and a Cy3-tagged generic anti-phosphotyrosine monoclonal antibody. Visualization of KIR phosphorylation in natural killer (NK) cells contacting target cells expressing cognate major histocompatibility complex class I proteins revealed that inhibitory signaling is spatially restricted to the immune synapse. This explains how NK cells respond appropriately when simultaneously surveying susceptible and resistant target cells. More surprising, phosphorylated KIR was confined to microclusters within the aggregate of KIR, contrary to an expected homogeneous distribution of KIR signaling across the immune synapse. Also, yellow fluorescent protein–tagged Lck, a kinase important for KIR phosphorylation, accumulated in a multifocal distribution at inhibitory synapses. Spatial confinement of receptor phosphorylation within the immune synapse may be critical to how activating and inhibitory signals are integrated in NK cells.
Fuchter MJ, Vesper BJ, Murphy KA, et al., 2005, ROM polymerization-capture-release strategy for the chromatography-free synthesis of novel unsymmetrical porphyrazines, JOURNAL OF ORGANIC CHEMISTRY, Vol: 70, Pages: 2793-2802, ISSN: 0022-3263
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- Citations: 22
Phillips D, 2005, The Lord Porter of Luddenham 6 December 1920-31 August 2002, PROCEEDINGS OF THE AMERICAN PHILOSOPHICAL SOCIETY, Vol: 149, Pages: 107-111, ISSN: 0003-049X
Treanor B, Lanigan PMP, Suhling K, et al., 2005, Imaging fluorescence lifetime heterogeneity applied to GFP-tagged MHC protein at an immunological synapse, JOURNAL OF MICROSCOPY-OXFORD, Vol: 217, Pages: 36-43, ISSN: 0022-2720
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- Citations: 53
Suhling K, French PMW, Phillips D, 2005, Time-resolved fluorescence microscopy, Photochemical & Photobiological Sciences, Vol: 4, Pages: 13-22, ISSN: 1474-905X
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