Imperial College London
Alternate

Dr David Laith Rawaf

Faculty of Medicine, School of Public Health

Web Editor for the WHO Collaborating Centre
 
 
 
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d.rawaf Website

 
 
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Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Reiner:2020:10.1016/S0140-6736(20)30114-8,
author = {Reiner, RC and Wiens, KE and Deshpande, A and Baumann, MM and Lindstedt, PA and Blacker, BF and Troeger, CE and Earl, L and Munro, SB and Abate, D and Abbastabar, H and Abd-Allah, F and Abdelalim, A and Abdollahpour, I and Abdulkader, RS and Abebe, G and Abegaz, KH and Abreu, LG and Abrigo, MRM and Accrombessi, MMK and Acharya, D and Adabi, M and Adebayo, OM and Adedoyin, RA and Adekanmbi, V and Adetokunboh, OO and Adham, D and Adhena, BM and Afarideh, M and Ahmadi, K and Ahmadi, M and Ahmed, AE and Ahmed, MB and Ahmed, R and Ajumobi, O and Akal, CG and Akalu, TY and Akanda, AS and Alamene, GM and Alanzi, TM and Albright, JR and Rabanal, JEA and Alemnew, BT and Alemu, ZA and Ali, BA and Ali, M and Alijanzadeh, M and Alipour, V and Aljunid, SM and Almasi, A and Almasi-Hashiani, A and Al-Mekhlafi, HM and Altirkawi, K and Alvis-Guzman, N and Alvis-Zakzuk, NJ and Amare, AT and Amini, S and Amit, AML and Andrei, CL and Anegago, MT and Anjomshoa, M and Ansari, F and Antonio, CAT and Antriyan},
doi = {10.1016/S0140-6736(20)30114-8},
journal = {The Lancet},
pages = {1779--1801},
title = {Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017},
url = {http://dx.doi.org/10.1016/S0140-6736(20)30114-8},
volume = {395},
year = {2020}
}
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TY  - JOUR
AB  - BackgroundAcross low-income and middle-income countries (LMICs), one in ten deaths in children younger than 5 years is attributable to diarrhoea. The substantial between-country variation in both diarrhoea incidence and mortality is attributable to interventions that protect children, prevent infection, and treat disease. Identifying subnational regions with the highest burden and mapping associated risk factors can aid in reducing preventable childhood diarrhoea.MethodsWe used Bayesian model-based geostatistics and a geolocated dataset comprising 15072746 children younger than 5 years from 466 surveys in 94 LMICs, in combination with findings of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017, to estimate posterior distributions of diarrhoea prevalence, incidence, and mortality from 2000 to 2017. From these data, we estimated the burden of diarrhoea at varying subnational levels (termed units) by spatially aggregating draws, and we investigated the drivers of subnational patterns by creating aggregated risk factor estimates.FindingsThe greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. Although children in much of Africa remain at high risk of death due to diarrhoea, regions with the most deaths were outside Africa, with the highest mortality units located in Pakistan. Indonesia showed the greatest within-country geographical inequality; some regions had mortality rates nearly four times the average country rate. Reductions in mortality were correlated to improvements in water, sanitation, and hygiene (WASH) or reductions in child growth failure (CGF). Similarly, most high-risk areas had poor WASH, high CGF, or low oral rehydration
AU  - Reiner,RC
AU  - Wiens,KE
AU  - Deshpande,A
AU  - Baumann,MM
AU  - Lindstedt,PA
AU  - Blacker,BF
AU  - Troeger,CE
AU  - Earl,L
AU  - Munro,SB
AU  - Abate,D
AU  - Abbastabar,H
AU  - Abd-Allah,F
AU  - Abdelalim,A
AU  - Abdollahpour,I
AU  - Abdulkader,RS
AU  - Abebe,G
AU  - Abegaz,KH
AU  - Abreu,LG
AU  - Abrigo,MRM
AU  - Accrombessi,MMK
AU  - Acharya,D
AU  - Adabi,M
AU  - Adebayo,OM
AU  - Adedoyin,RA
AU  - Adekanmbi,V
AU  - Adetokunboh,OO
AU  - Adham,D
AU  - Adhena,BM
AU  - Afarideh,M
AU  - Ahmadi,K
AU  - Ahmadi,M
AU  - Ahmed,AE
AU  - Ahmed,MB
AU  - Ahmed,R
AU  - Ajumobi,O
AU  - Akal,CG
AU  - Akalu,TY
AU  - Akanda,AS
AU  - Alamene,GM
AU  - Alanzi,TM
AU  - Albright,JR
AU  - Rabanal,JEA
AU  - Alemnew,BT
AU  - Alemu,ZA
AU  - Ali,BA
AU  - Ali,M
AU  - Alijanzadeh,M
AU  - Alipour,V
AU  - Aljunid,SM
AU  - Almasi,A
AU  - Almasi-Hashiani,A
AU  - Al-Mekhlafi,HM
AU  - Altirkawi,K
AU  - Alvis-Guzman,N
AU  - Alvis-Zakzuk,NJ
AU  - Amare,AT
AU  - Amini,S
AU  - Amit,AML
AU  - Andrei,CL
AU  - Anegago,MT
AU  - Anjomshoa,M
AU  - Ansari,F
AU  - Antonio,CAT
AU  - Antriyandarti,E
AU  - Appiah,SCY
AU  - Arabloo,J
AU  - Aremu,O
AU  - Armoon,B
AU  - Aryal,KK
AU  - Arzani,A
AU  - Asadi-Lari,M
AU  - Ashagre,AF
AU  - Atalay,HT
AU  - Atique,S
AU  - Atre,SR
AU  - Ausloos,M
AU  - Avila-Burgos,L
AU  - Awasthi,A
AU  - Awoke,N
AU  - Quintanilla,BPA
AU  - Ayano,G
AU  - Ayanore,MA
AU  - Ayele,AA
AU  - Aynalem,YA
AU  - Azari,S
AU  - Babaee,E
AU  - Badawi,A
AU  - Bakkannavar,SM
AU  - Balakrishnan,S
AU  - Bali,AG
AU  - Banach,M
AU  - Barac,A
AU  - Barnighausen,TW
AU  - Basaleem,H
AU  - Bassat,Q
AU  - Bayati,M
AU  - Bedi,N
AU  - Behzadifar,M
AU  - Behzadifar,M
AU  - Bekele,YA
AU  - Bell,ML
AU  - Bennett,DA
AU  - Berbada,DA
AU  - Beyranvand,T
AU  - Bhat,AG
AU  - Bhattacharyya,K
AU  - Bhattarai,S
AU  - Bhaumik,S
AU  - Bijani,A
AU  - Bikbov,B
AU  - Biswas,RK
AU  - Bogale,KA
AU  - Bohlouli,S
AU  - Brady,OJ
AU  - Bragazzi,NL
AU  - Briko,AN
AU  - Briko,NI
AU  - Nagaraja,SB
AU  - Butt,ZA
AU  - Campos-Nonato,IR
AU  - Rincon,JCC
AU  - Cardenas,R
AU  - Carvalho,F
AU  - Castro,F
AU  - Chansa,C
AU  - Chatterjee,P
AU  - Chattu,VK
AU  - Chauhan,BG
AU  - Chin,KL
AU  - Christopher,DJ
AU  - Chu,D-T
AU  - Claro,RM
AU  - Cormier,NM
AU  - Costa,VM
AU  - Damiani,G
AU  - Daoud,F
AU  - Dandona,L
AU  - Dandona,R
AU  - Darwish,AH
AU  - Daryani,A
AU  - Das,JK
AU  - Das,Gupta R
AU  - Dasa,TT
AU  - Davila,CA
AU  - Weaver,ND
AU  - Davitoiu,DV
AU  - De,Neve J-W
AU  - Demeke,FM
AU  - Demis,AB
AU  - Demoz,GT
AU  - Denova-Gutierrez,E
AU  - Deribe,K
AU  - Desalew,A
AU  - Dessie,GA
AU  - Dharmaratne,SD
AU  - Dhillon,P
AU  - Dhimal,M
AU  - Dhungana,GP
AU  - Diaz,D
AU  - Ding,EL
AU  - Diro,HD
AU  - Djalalinia,S
AU  - Do,HP
AU  - Doku,DT
AU  - Dolecek,C
AU  - Dubey,M
AU  - Dubljanin,E
AU  - Adema,BD
AU  - Dunachie,SJ
AU  - Duraes,AR
AU  - Duraisamy,S
AU  - Effiong,A
AU  - Eftekhari,A
AU  - El,S
DO  - 10.1016/S0140-6736(20)30114-8
EP  - 1801
PY  - 2020///
SN  - 0140-6736
SP  - 1779
TI  - Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000-17: analysis for the Global Burden of Disease Study 2017
T2  - The Lancet
UR  - http://dx.doi.org/10.1016/S0140-6736(20)30114-8
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000540993600024&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.sciencedirect.com/science/article/pii/S0140673620301148?via%3Dihub
UR  - http://hdl.handle.net/10044/1/80537
VL  - 395
ER  -
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