Imperial College London
Alternate

Dr David Laith Rawaf

Faculty of Medicine, School of Public Health

Web Editor for the WHO Collaborating Centre
 
 
 
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d.rawaf Website

 
 
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Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Bryazka:2022:10.1016/S0140-6736(22)00847-9,
author = {Bryazka, D and Reitsma, MB and Griswold, MG and Abate, KH and Abbafati, C and Abbasi-Kangevari, M and Abbasi-Kangevari, Z and Abdoli, A and Abdollahi, M and Abdullah, AYM and Abhilash, ES and Abu-Gharbieh, E and Acuna, JM and Addolorato, G and Adebayo, OM and Adekanmbi, V and Adhikari, K and Adhikari, S and Adnani, QES and Afzal, S and Agegnehu, WY and Aggarwal, M and Ahinkorah, BO and Ahmad, AR and Ahmad, S and Ahmad, T and Ahmadi, A and Ahmadi, S and Ahmed, H and Rashid, TA and Akunna, CJ and Al, Hamad H and Alam, MZ and Alem, DT and Alene, KA and Alimohamadi, Y and Alizadeh, A and Allel, K and Alonso, J and Alvand, S and Alvis-Guzman, N and Amare, F and Ameyaw, EK and Amiri, S and Ancuceanu, R and Anderson, JA and Andrei, CL and Andrei, T and Arabloo, J and Arshad, M and Artamonov, AA and Aryan, Z and Asaad, M and Asemahagn, MA and Astell-Burt, T and Athari, SS and Atnafu, DD and Atorkey, P and Atreya, A and Ausloos, F and Ausloos, M and Ayano, G and Ayanore, MA and Ayinde, OO and A},
doi = {10.1016/S0140-6736(22)00847-9},
journal = {The Lancet},
pages = {185--235},
title = {Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020},
url = {http://dx.doi.org/10.1016/S0140-6736(22)00847-9},
volume = {400},
year = {2022}
}
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TY  - JOUR
AB  - BackgroundThe health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year.MethodsFor this analysis, we constructed burden-weighted dose–response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020 for 21 regions, including 204 countries and territories, by 5-year age group, sex, and year for individuals aged 15–95 years and older from 1990 to 2020. Based on the NDE, we quantified the population consuming harmful amounts of alcohol.FindingsThe burden-weighted relative risk curves for alcohol use varied by region and age. Among individuals aged 15–39 years in 2020, the TMREL varied between 0 (95% uncertainty interval 0–0) and 0·603 (0·400–1·00) standard drinks per day, and the NDE varied between 0·002 (0–0) and 1·75 (0·698–4·30) standard drinks per day. Among individuals aged 40 years and older, the burden-weighted relative risk curve was J-shaped for all regions, with a 2020 TMREL that ranged from 0·114 (0–0·403) to 1·87 (0·500–3·30) standard drinks per day and an NDE that ranged between 0·193 (0–0·900) and 6·94 (3·40–8·30) standard drinks per day. Among individuals consuming harmful amounts of alcohol in 2020, 59·1% (54·3–65·4) were aged 15–39 years and 76·9% (73·0–81·3) were male.InterpretationThere is stron
AU  - Bryazka,D
AU  - Reitsma,MB
AU  - Griswold,MG
AU  - Abate,KH
AU  - Abbafati,C
AU  - Abbasi-Kangevari,M
AU  - Abbasi-Kangevari,Z
AU  - Abdoli,A
AU  - Abdollahi,M
AU  - Abdullah,AYM
AU  - Abhilash,ES
AU  - Abu-Gharbieh,E
AU  - Acuna,JM
AU  - Addolorato,G
AU  - Adebayo,OM
AU  - Adekanmbi,V
AU  - Adhikari,K
AU  - Adhikari,S
AU  - Adnani,QES
AU  - Afzal,S
AU  - Agegnehu,WY
AU  - Aggarwal,M
AU  - Ahinkorah,BO
AU  - Ahmad,AR
AU  - Ahmad,S
AU  - Ahmad,T
AU  - Ahmadi,A
AU  - Ahmadi,S
AU  - Ahmed,H
AU  - Rashid,TA
AU  - Akunna,CJ
AU  - Al,Hamad H
AU  - Alam,MZ
AU  - Alem,DT
AU  - Alene,KA
AU  - Alimohamadi,Y
AU  - Alizadeh,A
AU  - Allel,K
AU  - Alonso,J
AU  - Alvand,S
AU  - Alvis-Guzman,N
AU  - Amare,F
AU  - Ameyaw,EK
AU  - Amiri,S
AU  - Ancuceanu,R
AU  - Anderson,JA
AU  - Andrei,CL
AU  - Andrei,T
AU  - Arabloo,J
AU  - Arshad,M
AU  - Artamonov,AA
AU  - Aryan,Z
AU  - Asaad,M
AU  - Asemahagn,MA
AU  - Astell-Burt,T
AU  - Athari,SS
AU  - Atnafu,DD
AU  - Atorkey,P
AU  - Atreya,A
AU  - Ausloos,F
AU  - Ausloos,M
AU  - Ayano,G
AU  - Ayanore,MA
AU  - Ayinde,OO
AU  - Ayuso-Mateos,JL
AU  - Azadnajafabad,S
AU  - Azanaw,MM
AU  - Azangou-Khyavy,M
AU  - Jafari,AA
AU  - Azzam,AY
AU  - Badiye,AD
AU  - Bagheri,N
AU  - Bagherieh,S
AU  - Bairwa,M
AU  - Bakkannavar,SM
AU  - Bakshi,RK
AU  - Balchut-Bilchut,AH
AU  - Barra,F
AU  - Barrow,A
AU  - Baskaran,P
AU  - Belo,L
AU  - Bennett,DA
AU  - Bensenor,IM
AU  - Bhagavathula,AS
AU  - Bhala,N
AU  - Bhalla,A
AU  - Bhardwaj,N
AU  - Bhardwaj,P
AU  - Bhaskar,S
AU  - Bhattacharyya,K
AU  - Bhojaraja,VS
AU  - Bintoro,BS
AU  - Blokhina,EAE
AU  - Bodicha,BBA
AU  - Boloor,A
AU  - Bosetti,C
AU  - Braithwaite,D
AU  - Brenner,H
AU  - Briko,NI
AU  - Brunoni,AR
AU  - Butt,ZA
AU  - Cao,C
AU  - Cao,Y
AU  - Cardenas,R
AU  - Carvalho,AF
AU  - Carvalho,M
AU  - Castaldelli-Maia,JM
AU  - Castelpietra,G
AU  - Castro-de-Araujo,LFS
AU  - Cattaruzza,MS
AU  - Chakraborty,PA
AU  - Charan,J
AU  - Chattu,VK
AU  - Chaurasia,A
AU  - Cherbuin,N
AU  - Chu,D-T
AU  - Chudal,N
AU  - Chung,S-C
AU  - Churko,C
AU  - Ciobanu,LG
AU  - Cirillo,M
AU  - Claro,RM
AU  - Costanzo,S
AU  - Cowden,RG
AU  - Criqui,MH
AU  - Cruz-Martins,N
AU  - Culbreth,GT
AU  - Dachew,BA
AU  - Dadras,O
AU  - Dai,X
AU  - Damiani,G
AU  - Dandona,L
AU  - Dandona,R
AU  - Daniel,BD
AU  - Danielewicz,A
AU  - Gela,JD
AU  - Davletov,K
AU  - Paiva,de Araujo JA
AU  - De,Sa-Junior AR
AU  - Debela,SA
AU  - Dehghan,A
AU  - Demetriades,AK
AU  - Molla,MD
AU  - Desai,R
AU  - Desta,AA
AU  - da,Silva DD
AU  - Diaz,D
AU  - Digesa,LE
AU  - Diress,M
AU  - Dodangeh,M
AU  - Dongarwar,D
AU  - Dorostkar,F
AU  - Dsouza,HL
AU  - Duko,B
AU  - Duncan,BB
AU  - Edvardsson,K
AU  - Ekholuenetale,M
AU  - Elgar,FJ
AU  - Elhadi,M
AU  - Elmonem,MA
AU  - Endries,AY
AU  - Eskandarieh,S
AU  - Etemadimanesh,A
AU  - Fagbamigbe,AF
AU  - Fakhradiyev,IR
AU  - Farahmand,F
AU  - Fa
DO  - 10.1016/S0140-6736(22)00847-9
EP  - 235
PY  - 2022///
SN  - 0140-6736
SP  - 185
TI  - Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020
T2  - The Lancet
UR  - http://dx.doi.org/10.1016/S0140-6736(22)00847-9
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000843984100001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.sciencedirect.com/science/article/pii/S0140673622008479?via%3Dihub
UR  - http://hdl.handle.net/10044/1/99607
VL  - 400
ER  -
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