Imperial College London

ProfessorDanielRueckert

Faculty of EngineeringDepartment of Computing

Head of Department of Computing
 
 
 
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Contact

 

+44 (0)20 7594 8333d.rueckert Website

 
 
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Location

 

568Huxley BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Vasylechko:2015:10.1002/mrm.25299,
author = {Vasylechko, S and Malamateniou, C and Nunes, RG and Fox, M and Allsop, J and Rutherford, M and Rueckert, D and Hajnal, JV},
doi = {10.1002/mrm.25299},
journal = {MAGNETIC RESONANCE IN MEDICINE},
pages = {1795--1802},
title = {T2*Relaxometry of Fetal Brain at 1.5 Tesla Using a Motion Tolerant Method},
url = {http://dx.doi.org/10.1002/mrm.25299},
volume = {73},
year = {2015}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - PurposeThe aim of this study was to determine T2 values for the fetal brain in utero and to compare them with previously reported values in preterm and term neonates. Knowledge of T2 may be useful for assessing brain development, brain abnormalities, and for optimizing functional imaging studies.MethodsMaternal respiration and unpredictable fetal motion mean that conventional multishot acquisition techniques used in adult T2 relaxometry studies are not practical. Single shot multiecho echo planar imaging was used as a rapid method for measuring fetal T2 by effectively freezing intra-slice motion.ResultsT2 determined from a sample of 24 subjects correlated negatively with gestational age with mean values of 220 ms (±45) for frontal white matter, 159 ms (±32) for thalamic gray matter, and 236 ms (±45) for occipital white matter.ConclusionFetal T2 values are higher than those previously reported for preterm neonates and decline with a consistent trend across gestational age. The data suggest that longer than usual echo times or direct T2 measurement should be considered when performing fetal fMRI to reach optimal BOLD sensitivity.
AU - Vasylechko,S
AU - Malamateniou,C
AU - Nunes,RG
AU - Fox,M
AU - Allsop,J
AU - Rutherford,M
AU - Rueckert,D
AU - Hajnal,JV
DO - 10.1002/mrm.25299
EP - 1802
PY - 2015///
SN - 0740-3194
SP - 1795
TI - T2Relaxometry of Fetal Brain at 1.5 Tesla Using a Motion Tolerant Method
T2 - MAGNETIC RESONANCE IN MEDICINE
UR - http://dx.doi.org/10.1002/mrm.25299
VL - 73
ER -