Imperial College London
Alternate

ProfessorDanielRueckert

Faculty of Engineering, Department of Computing

Professor of Visual Information Processing
 
 
 
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Contact

 

+44 (0)20 7594 8333d.rueckert Website

 
 
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Location

 

568Huxley BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Cruz:2023:10.1002/nbm.4942,
author = {Cruz, G and Hammernik, K and Kuestner, T and Velasco, C and Hua, A and Ismail, TF and Rueckert, D and Botnar, RM and Prieto, C},
doi = {10.1002/nbm.4942},
journal = {NMR in Biomedicine},
pages = {1--16},
title = {Single-heartbeat cardiac cine imaging via jointly regularized non-rigid motion corrected reconstruction},
url = {http://dx.doi.org/10.1002/nbm.4942},
volume = {36},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - PURPOSE: Develop a novel approach for 2D breath-hold cardiac cine from a single heartbeat, by combining cardiac motion corrected reconstructions and non-rigidly aligned patch-based regularization. METHODS: Conventional cardiac cine imaging is obtained via motion resolved reconstructions of data acquired over multiple heartbeats. Here, we achieve single-heartbeat cine imaging by incorporating non-rigid cardiac motion correction into the reconstruction of each cardiac phase, in conjunction with a motion-aligned patch-based regularization. The proposed Motion Corrected CINE (MC-CINE) incorporates all acquired data into the reconstruction of each (motion corrected) cardiac phase, resulting in a better posed problem than motion resolved approaches. MC-CINE was compared to iterative SENSE and XD-GRASP in fourteen healthy subjects in terms of image sharpness, reader scoring (1-5 range) and reader ranking (1-9 range) of image quality, and single-slice left ventricular assessment. RESULTS: MC-CINE was significantly superior to both iterative SENSE and XD-GRASP using 20, 2 and 1 heartbeat(s). Iterative SENSE, XD-GRASP and MC-CINE achieved sharpness of 74%, 74% and 82% using 20 heartbeats, and 53%, 66% and 82% with 1 heartbeat, respectively. Corresponding results for reader scores were 4.0, 4.7 and 4.9, with 20 heartbeats, and 1.1, 3.0 and 3.9 with 1 heartbeat. Corresponding results for reader rankings were 5.3, 7.3 and 8.6 with 20 heartbeats, and 1.0, 3.2 and 5.4 with 1 heartbeat. MC-CINE using a single heartbeat presented non-significant differences in image quality to iterative SENSE with 20 heartbeats. MC-CINE and XD-GRASP at one heartbeat both presented a non-significant negative bias of <2% in ejection fraction relative to the reference iterative SENSE. CONCLUSION: The proposed MC-CINE significantly improves image quality relative to iterative SENSE and XD-GRASP, enabling 2D cine from a single heartbeat.
AU  - Cruz,G
AU  - Hammernik,K
AU  - Kuestner,T
AU  - Velasco,C
AU  - Hua,A
AU  - Ismail,TF
AU  - Rueckert,D
AU  - Botnar,RM
AU  - Prieto,C
DO  - 10.1002/nbm.4942
EP  - 16
PY  - 2023///
SN  - 0952-3480
SP  - 1
TI  - Single-heartbeat cardiac cine imaging via jointly regularized non-rigid motion corrected reconstruction
T2  - NMR in Biomedicine
UR  - http://dx.doi.org/10.1002/nbm.4942
UR  - https://www.ncbi.nlm.nih.gov/pubmed/36999225
UR  - https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/nbm.4942
UR  - http://hdl.handle.net/10044/1/103722
VL  - 36
ER  -
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