MrDuncanSpalding

Faculty of Medicine, Department of Surgery & Cancer

Clinical Senior Lecturer in Hepato-Biliary Surgery

Contact

+44 (0)20 3313 3941d.spalding

Location

Hammersmith HospitalHammersmith Campus

Summary

Clinical Senior Lecturer and Honorary Consultant in Hepatobiliary and Pancreatic Surgery. Has a clinical interest in HPB Surgery with a specific focus on minimally invasive techniques, the use of radiofrequency energy as a resection tool, cholangiocarcinomas and neuroendocrine tumours.

Qualifications

BSc in Biochemistry, University of Southampton, 1985
MB ChB, University of Birmingham, 1989
FRCS (Eng), 1993
FRCS (Gen Surg), 2002
MD, University of London, 2006

Research Interests

Molecular pathogenesis of cholangiocarcinomas to identify novel therapeutic targets.
Early detection of cholangiocarcinomas using novel biomarkers
Synthesis of novel molecular conjugates comprising chemotherapeutic agents and transporter molecules for targeted delivery to cholangiocarcinomas.
Stellate cancer-associated fibroblasts contribution to chemoresistance of pancreatic ductal adenocarcinoma.

Membership of Professional Bodies

Association of Surgeons of Great Britain and Ireland
Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland
Fellow of the Royal College of Surgeons of England
International Hepatopancreatobiliary Association
Royal Society of Medicine
British Medical Association

Teaching Activities

Undergraduate Teaching

Module leader BSc in Surgery and Anaesthesia (Module 1: Regeneration, repair and cancer control).
BSc in Gastroenterology and Hepatology

Postgraduate Teaching

MSc in Surgical Science
MSc in Surgical Technology

Invited Teaching

Whipps Cross Higher Surgery Course

Postgraduate Supervision

Supervising 2 PhD, 2 MSc and 1 MRes Projects

Editorial Boards

Sub-editor of the Journal of HPB Surgery

Publications

Journals

Hashimoto A, Sarker D, Reebye V, et al.Hashimoto A, Sarker D, Reebye V, Jarvis S, Sodergren MH, Kossenkov A, Raulf N, Vasara J, Andrikakou P, Meyer T, Huang K-W, Plummer R, Chee CE, Spalding D, Pai M, Pinato DJ, Sharma R, Basu B, Palmer D, Ma Y-T, Habib R, Martirosyan A, Elasri N, Reynaud A, Rossi J, Cobbold M, Habib N, Gabrilovich D close, 2021, Up-regulation of C/EBP alpha inhibits suppressive activity of myeloid cells and potentiates antitumor response in mice and cancer patients., Cancer Research, Vol:81, ISSN:0008-5472

Author Web Link

Pinato D, Cortellini A, Sukumaran A, et al.Pinato D, Cortellini A, Sukumaran A, Cole T, Pai M, Habib N, Spalding D, Sodergren M, Martinez M, Dhillon T, Tait P, Thomas R, Ward C, Kocher H, Yip V, Slater S, Sharma R close, 2021, PRIME-HCC: Phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma, Bmc Cancer, Vol:21, ISSN:1471-2407

McKay SC, Pathak S, Wilkin RJW, et al.McKay SC, Pathak S, Wilkin RJW, Kamarajah SK, Wigmore SJ, Rees J, Dunne DFJ, Garcea G, Ahmad J, de Liguori Carino N, Sultana A, Silva M, Lykoudis P, Nasralla D, Milburn J, Shah N, Kocher HM, Bhogal R, Baron RD, Navarro A, Halle-Smith J, Al-Sarireh B, Sen G, Jamieson NB, Briggs C, Stell D, Aroori S, Bowles M, Kanwar A, Harper S, Menon K, Prachalias A, Srinivasan P, Frampton AE, Jones C, Arshad A, Tait I, Spalding D, Young AL, Durkin D, Ghods-Ghorbani M, Sutcliffe RP, Roberts KJ close, 2021, Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience., Hpb (oxford)

Glasbey JC, Omar O, Nepogodiev D, et al.Glasbey JC, Omar O, Nepogodiev D, Minaya-Bravo A, Bankhead-Kendall BK, Fiore M, Futaba K, Gabre-Kidan A, Gujjuri RR, Isik A, Kaafarani HMA, Kamarajah SK, Li E, Loeffler MW, McLean KA, Outani O, Ntirenganya F, Satoi S, Shaw R, Simoes JFF, Stewart GD, Tabiri S, Trout IM, Bhangu AA, Glasbey JC, Omar O, Bhangu AA, Siaw-Acheampong K, Benson RA, Bywater E, Chaudhry D, Dawson BE, Evans JP, Glasbey JC, Gujjuri RR, Heritage E, Jones CS, Kamarajah SK, Khatri C, Khaw RA, Keatley JM, Knight A, Lawday S, Li E, Mann HS, Marson EJ, McLean KA, Mckay SC, Mills EC, Nepogodiev D, Pellino G, Picciochi M, Taylor EH, Tiwari A, Simoes JFF, Trout IM, Venn ML, Wilkin RJW, Bhangu A, Glasbey JC, Smart NJ, Minaya-Bravo A, Evans JP, Gallo G, Moug S, Pata F, Pockney P, Di Saverio S, Vallance A, Vimalchandran D, Griffiths EA, Kamarajah SK, Evans RPT, Townend P, Roberts K, McKay S, Isaac J, Satoi S, Edwards J, Coonar AS, Marchbank A, Caruana EJ, Layton GR, Patel A, Brunelli A, Ford S, Desai A, Gronchi A, Fiore M, Almond M, Tirotta F, Dumitra S, Kolias A, Price SJ, Fountain DM, Jenkinson MD, Hutchinson P, Marcus HJ, Piper RJ, Lippa L, Servadei F, Esene I, Freyschlag C, Neville I, Rosseau G, Schaller K, Demetriades AK, Robertson F, Alamri A, Shaw R, Schache AG, Winter SC, Ho M, Nankivell P, Biel JR, Batstone M, Ganly I, Vidya R, Wilkins A, Singh JK, Thekinkattil D, Sundar S, Fotopoulou C, Leung E, Khan T, Chiva L, Sehouli J, Fagotti A, Cohen P, Gutelkin M, Ghebre R, Konney T, Pareja R, Bristow R, Dowdy S, Rajkumar STS, Ng J, Fujiwara K, Stewart GD, Lamb B, Narahari K, McNeill A, Colquhoun A, McGrath J, Bromage S, Barod R, Kasivisvanathan V, Klatte T, Simoes JFF, Abbott TEF, Abukhalaf S, Adamina M, Ademuyiwa AO, Agarwal A, Akkulak M, Alameer E, Alderson D, Alakaloko F, Albertsmeiers M, Alser O, Alshaar M, Alshryda S, Arnaud AP, Augestad KM, Ayasra F, Azevedo J, Bankhead-Kendall BK, Barlow E, Beard D, Benson RA, Blanco-Colino R, Brar A, Minaya-Bravo A, Breen KA, Bretherton C, Buarque IL, Burke J, Caru close, 2021, Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic, British Journal of Surgery, Vol:108, ISSN:0007-1323, Pages:88-96

Gavriilidis P, Sutcliffe RP, Roberts KJ, et al.Gavriilidis P, Sutcliffe RP, Roberts KJ, Pai M, Spalding D, Habib N, Jiao LR, Sodergren MH close, 2020, No difference in mortality among ALPPS, two-staged hepatectomy, and portal vein embolization/ligation: A systematic review by updated traditional and network meta-analyses, Hepatobiliary & Pancreatic Diseases International, Vol:19, ISSN:1499-3872, Pages:411-419

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