Imperial College London


Faculty of MedicineDepartment of Surgery & Cancer

Clinical Senior Lecturer in Hepato-Biliary Surgery



+44 (0)20 3313 3941d.spalding




Hammersmith HospitalHammersmith Campus






Clinical Senior Lecturer and Honorary Consultant in Hepatobiliary and Pancreatic Surgery. Has a clinical interest in HPB Surgery with a specific focus on minimally invasive techniques, the use of radiofrequency energy as a resection tool, cholangiocarcinomas and neuroendocrine tumours.



  • BSc in Biochemistry, University of Southampton, 1985
  • MB ChB, University of Birmingham, 1989
  • FRCS (Eng), 1993
  • FRCS (Gen Surg), 2002
  • MD, University of London, 2006

 Research Interests

  • Molecular pathogenesis of cholangiocarcinomas to identify novel therapeutic targets.
  • Early detection of cholangiocarcinomas using novel biomarkers
  • Synthesis of novel molecular conjugates comprising chemotherapeutic agents and transporter molecules for targeted delivery to cholangiocarcinomas.
  • Stellate cancer-associated fibroblasts contribution to chemoresistance of pancreatic ductal adenocarcinoma.

Membership of Professional Bodies

  • Association of Surgeons of Great Britain and Ireland
  • Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland
  • Fellow of the Royal College of Surgeons of England
  • International Hepatopancreatobiliary Association
  • Royal Society of Medicine
  • British Medical Association

 Teaching Activities

Undergraduate Teaching

  • Module leader BSc in Surgery and Anaesthesia (Module 1: Regeneration, repair and cancer control).
  • BSc in Gastroenterology and Hepatology

  Postgraduate Teaching

  • MSc in Surgical Science
  • MSc in Surgical Technology

 Invited Teaching

  • Whipps Cross Higher Surgery Course

  Postgraduate Supervision

  • Supervising 2 PhD, 2 MSc and 1 MRes Projects  

 Editorial Boards  

  • Sub-editor of the Journal of HPB Surgery 



Russell TB, Labib PL, Denson J, et al., 2023, Does an extensive diagnostic workup for upfront resectable pancreatic cancer result in a delay which affects survival? Results from an international multicentre study., Ann Hepatobiliary Pancreat Surg

Russell TB, Labib PL, Ausania F, et al., 2023, Serious complications of pancreatoduodenectomy correlate with lower rates of adjuvant chemotherapy: Results from the recurrence after Whipple's (RAW) study., Eur J Surg Oncol, Vol:49

Russell TB, Labib PL, Denson J, et al., 2023, Predictors of actual five-year survival and recurrence after pancreatoduodenectomy for ampullary adenocarcinoma: results from an international multicentre retrospective cohort study., Hpb (oxford), Vol:25, Pages:788-797

Reccia I, Pai M, Kumar J, et al., 2023, Tumour Heterogeneity and the Consequent Practical Challenges in the Management of Gastroenteropancreatic Neuroendocrine Neoplasms., Cancers (basel), Vol:15, ISSN:2072-6694

Avari P, Eng PC, Hu M, et al., 2023, A novel somatic mutation implicates ATP6V0D1 in proinsulin processing, Journal of the Endocrine Society, Vol:7, ISSN:2472-1972, Pages:1-5

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