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@article{Osmanov:2022:10.1183/13993003.01341-2021,
author = {Osmanov, IM and Spiridonova, E and Bobkova, P and Gamirova, A and Shikhaleva, A and Andreeva, M and Blyuss, O and El-Taravi, Y and DunnGalvin, A and Comberiati, P and Peroni, DG and Apfelbacher, C and Genuneit, J and Mazankova, L and Miroshina, A and Chistyakova, E and Samitova, E and Borzakova, S and Bondarenko, E and Korsunskiy, AA and Konova, I and Hanson, SW and Carson, G and Sigfrid, L and Scott, JT and Greenhawt, M and Whittaker, EA and Garralda, E and Swann, O and Buonsenso, D and Nicholls, DE and Simpson, F and Jones, C and Semple, MG and Warner, JO and Vos, T and Olliaro, P and Munblit, D and Sechenov, StopCOVID Research Team},
doi = {10.1183/13993003.01341-2021},
journal = {European Respiratory Journal},
title = {Risk factors for long covid in previoulsy hospitalsied children using the ISARIC Global Follow-Up Protocol: a prospective cohort study},
url = {http://dx.doi.org/10.1183/13993003.01341-2021},
volume = {59},
year = {2022}
}

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TY  - JOUR
AB  - Background The long-term sequelae of coronavirus disease 2019 (Covid-19) in children remain poorly characterised. This study aimed to assess long-term outcomes in children previously hospitalised with Covid-19 and associated risk factors.Methods This is a prospective cohort study of children (≤18years old) admitted with confirmed Covid-19. Children admitted to the hospital between April 2, 2020 and August 26, 2020, were included. Telephone interview using the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) Covid-19 Health and Wellbeing paediatric follow-up survey. Persistent symptoms (>5months) were further categorised by system(s) involved.Findings 518 of 853 (61%) of eligible children were available for the follow-up assessment and included in the study. Median age was 10.4years (IQR, 3–15.2) and 270 (52.1%) were girls; median follow-up since hospital discharge was 256 (223–271) days. At the time of the follow-up interview 126 (24.3%) participants reported persistent symptoms among which fatigue (53, 10.7%), sleep disturbance (36, 6.9%,) and sensory problems (29, 5.6%) were the most common. Multiple symptoms were experienced by 44 (8.4%) participants. Risk factors for persistent symptoms were: older age “6–11 years” (odds ratio 2.74 (95% confidence interval 1.37 to 5.75) and “12–18 years” (2.68, 1.41 to 5.4); and a history of allergic diseases (1.67, 1.04 to 2.67).Interpretation A quarter of children experienced persistent symptoms months after hospitalization with acute covid-19 infection, with almost one in ten experiencing multi-system involvement. Older age and allergic diseases were associated with higher risk of persistent symptoms at follow-up.
AU  - Osmanov,IM
AU  - Spiridonova,E
AU  - Bobkova,P
AU  - Gamirova,A
AU  - Shikhaleva,A
AU  - Andreeva,M
AU  - Blyuss,O
AU  - El-Taravi,Y
AU  - DunnGalvin,A
AU  - Comberiati,P
AU  - Peroni,DG
AU  - Apfelbacher,C
AU  - Genuneit,J
AU  - Mazankova,L
AU  - Miroshina,A
AU  - Chistyakova,E
AU  - Samitova,E
AU  - Borzakova,S
AU  - Bondarenko,E
AU  - Korsunskiy,AA
AU  - Konova,I
AU  - Hanson,SW
AU  - Carson,G
AU  - Sigfrid,L
AU  - Scott,JT
AU  - Greenhawt,M
AU  - Whittaker,EA
AU  - Garralda,E
AU  - Swann,O
AU  - Buonsenso,D
AU  - Nicholls,DE
AU  - Simpson,F
AU  - Jones,C
AU  - Semple,MG
AU  - Warner,JO
AU  - Vos,T
AU  - Olliaro,P
AU  - Munblit,D
AU  - Sechenov,StopCOVID Research Team
DO  - 10.1183/13993003.01341-2021
PY  - 2022///
SN  - 0903-1936
TI  - Risk factors for long covid in previoulsy hospitalsied children using the ISARIC Global Follow-Up Protocol: a prospective cohort study
T2  - European Respiratory Journal
UR  - http://dx.doi.org/10.1183/13993003.01341-2021
UR  - http://hdl.handle.net/10044/1/90185
VL  - 59
ER  -

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DR. DANIEL MUNBLIT

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