Imperial College London
Alternate

ProfessorDavidBrooks

Faculty of Medicine, Department of Brain Sciences

Visiting Professor
 
 
 
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Contact

 

david.brooks

 
 
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Assistant

 

Ms Hyacinth Henry +44 (0)20 3313 3172

 
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Location

 

U106Block B Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

1046 results found

KEW JJM, RIDDING MC, ROTHWELL JC, PASSINGHAM RE, LEIGH PN, SOORIAKUMARAN S, FRACKOWIAK RSJ, BROOKS DJet al., 1994, REORGANIZATION OF CORTICAL BLOOD-FLOW AND TRANSCRANIAL MAGNETIC STIMULATION MAPS IN HUMAN-SUBJECTS AFTER UPPER-LIMB AMPUTATION, JOURNAL OF NEUROPHYSIOLOGY, Vol: 72, Pages: 2517-2524, ISSN: 0022-3077

Journal article

ANDERSON TJ, JENKINS IH, BROOKS DJ, HAWKEN MB, FRACKOWIAK RSJ, KENNARD Cet al., 1994, CORTICAL CONTROL OF SACCADES AND FIXATION IN MAN - A PET STUDY, BRAIN, Vol: 117, Pages: 1073-1084, ISSN: 0006-8950

Journal article

Anderson TJ, Jenkins IH, Brooks DJ, Hawken MB, Frackowiak RS, Kennard Cet al., 1994, Cortical control of saccades and fixation in man. A PET study., Brain, Vol: 117 ( Pt 5), Pages: 1073-1084, ISSN: 0006-8950

To identify cortical regions activated during saccades and visual fixation, regional cerebral blood flow (rCBF) was measured in eight healthy subjects using C15O2 PET during the performance of three tasks: (i) central fixation; (ii) reflexive saccades to random targets; (iii) remembered saccades to locations of recent target appearance. Significant rCBF increases were identified using analysis of covariance and the t statistic (P < 0.001). Compared with central fixation there was activation of striate and extra-striate cortex, posterior parietal cortex (PPC) and frontal eye fields (FEF) during both reflexive and remembered saccades. During remembered saccades there was additional activation of supplementary motor area (SMA), insula, cingulate, thalamus, midbrain, cerebellum and right superior temporal gyrus (Brodmann's area 22). Compared with the individual saccadic tasks, central fixation activated extensive regions of ventromedial (areas 10, 11 and 32) and anterolateral (areas 8, 9, 10, 45 and 46) prefrontal cortex, and foveal visual cortex. We conclude that FEF and PPC are associated with the generation of both reflexive and remembered saccades, with SMA additionally involved during remembered saccades. Sustained voluntary fixation is mediated by prefrontal cortex.

Journal article

WILLS AJ, JENKINS IH, THOMPSON PD, FINDLEY LJ, BROOKS DJet al., 1994, RED NUCLEAR AND CEREBELLAR BUT NO OLIVARY ACTIVATION-ASSOCIATED WITH ESSENTIAL TREMOR - A POSITRON EMISSION TOMOGRAPHIC STUDY, ANNALS OF NEUROLOGY, Vol: 36, Pages: 636-642, ISSN: 0364-5134

Journal article

CEBALLOSBAUMANN AO, OBESO JA, VITEK JL, DELONG MR, BAKAY R, LINAZASORO G, BROOKS DJet al., 1994, RESTORATION OF THALAMOCORTICAL ACTIVITY AFTER POSTEROVENTRAL PALLIDOTOMY IN PARKINSONS-DISEASE, LANCET, Vol: 344, Pages: 814-814, ISSN: 0140-6736

Journal article

RING HA, BENCH CJ, TRIMBLE MR, BROOKS DJ, FRACKOWIAK RSJ, DOLAN RJet al., 1994, DEPRESSION IN PARKINSONS-DISEASE - A POSITRON EMISSION STUDY, BRITISH JOURNAL OF PSYCHIATRY, Vol: 165, Pages: 333-339, ISSN: 0007-1250

Journal article

PREVETT MC, CUNNINGHAM VJ, BROOKS DJ, FISH DR, DUNCAN JSet al., 1994, OPIATE RECEPTORS IN IDIOPATHIC GENERALIZED EPILEPSY MEASURED WITH [C-11] DIPRENORPHINE AND POSITRON EMISSION TOMOGRAPHY, EPILEPSY RESEARCH, Vol: 19, Pages: 71-77, ISSN: 0920-1211

Journal article

ABRAHAMS S, KEW JJM, GOLDSTEIN LH, BROOKS DJ, LEIGH PNet al., 1994, FRONTAL-LOBE FUNCTION IN AMYOTROPHIC-LATERAL-SCLEROSIS - A POSITRON EMISSION TOMOGRAPHY STUDY, Publisher: LITTLE BROWN CO, Pages: 273-273, ISSN: 0364-5134

Conference paper

REYNOLDS GP, PEARSON SJ, 1994, GLUTAMATE IN HUNTINGTONS-DISEASE, LANCET, Vol: 344, Pages: 189-189, ISSN: 0140-6736

Journal article

Blunt SB, Fuller G, Kennard C, Brooks Det al., 1994, Orolingual dystonia with "tip of the tongue" geste., Mov Disord, Vol: 9, ISSN: 0885-3185

Journal article

SAWLE GV, BURN DJ, MORRISH PK, LAMMERTSMA AA, SNOW BJ, LUTHRA S, OSMAN S, BROOKS DJet al., 1994, THE EFFECT OF ENTACAPONE (OR-611) ON BRAIN [F-18] 6-L-FLUORODOPA METABOLISM - IMPLICATIONS FOR LEVODOPA THERAPY OF PARKINSONS-DISEASE, NEUROLOGY, Vol: 44, Pages: 1292-1297, ISSN: 0028-3878

Journal article

KEW JJM, BROOKS DJ, RASSINGHAM RE, ROTHWELL JC, FRACKOWIAK RSJ, LEIGH PNet al., 1994, CORTICAL FUNCTION IN PROGRESSIVE MUSCULAR-ATROPHY AND AMYOTROPHIC-LATERAL-SCLEROSIS, Publisher: ELSEVIER SCIENCE BV, Pages: 72-72, ISSN: 0022-510X

Conference paper

BLUNT SB, FULLER G, KENNARD C, BROOKS Det al., 1994, OROLINGUAL DYSTONIA WITH TIP OF THE TONGUE GESTE, MOVEMENT DISORDERS, Vol: 9, Pages: 466-466, ISSN: 0885-3185

Journal article

KEW JJM, BROOKS DJ, PASSINGHAM RE, ROTHWELL JC, FRACKOWIAK RSJ, LEIGH PNet al., 1994, CORTICAL FUNCTION IN PROGRESSIVE LOWER MOTOR-NEURON DISORDERS AND AMYOTROPHIC-LATERAL-SCLEROSIS - A COMPARATIVE PET STUDY, NEUROLOGY, Vol: 44, Pages: 1101-1110, ISSN: 0028-3878

Journal article

TURJANSKI N, SAWLE GV, PLAYFORD ED, WEEKS R, LAMMERSTMA AA, LEES AJ, BROOKS DJet al., 1994, PET STUDIES OF THE PRESYNAPTIC AND POSTSYNAPTIC DOPAMINERGIC SYSTEM IN TOURETTES-SYNDROME, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol: 57, Pages: 688-692, ISSN: 0022-3050

Journal article

JENKINS IH, BROOKS DJ, NIXON PD, FRACKOWIAK RSJ, PASSINGHAM REet al., 1994, MOTOR SEQUENCE LEARNING - A STUDY WITH POSITRON EMISSION TOMOGRAPHY, JOURNAL OF NEUROSCIENCE, Vol: 14, Pages: 3775-3790, ISSN: 0270-6474

Journal article

Taylor-Robinson SD, Weeks RA, Sargentoni J, Marcus CD, Bryant DJ, Harding AE, Brooks DJet al., 1994, Evidence for glutamate excitotoxicity in Huntington's disease with proton magnetic resonance spectroscopy., Lancet, Vol: 343, ISSN: 0140-6736

Journal article

Baxter AG, Cooke A, 1994, Peptide therapy for diabetes., Lancet, Vol: 343, ISSN: 0140-6736

Journal article

TAYLORROBINSON SD, WEEKS RA, SARGENTONI J, MARCUS CD, BRYANT DJ, HARDING AE, BROOKS DJet al., 1994, EVIDENCE FOR GLUTAMATE EXCITOTOXICITY IN HUNTINGTONS-DISEASE WITH PROTON MAGNETIC-RESONANCE SPECTROSCOPY, LANCET, Vol: 343, Pages: 1170-1170, ISSN: 0140-6736

Journal article

WEEKS RA, LEES AJ, BROOKS DJ, 1994, TOURETTES-SYNDROME AND THE OPIOID SYSTEM, LANCET, Vol: 343, Pages: 1107-1108, ISSN: 0140-6736

Journal article

Cruickshank JM, 1994, Relation between aortic atherosclerosis and blood pressure., Lancet, Vol: 343, ISSN: 0140-6736

Journal article

SAWLE GV, PLAYFORD ED, BURN DJ, CUNNINGHAM VJ, BROOKS DJet al., 1994, SEPARATING PARKINSONS-DISEASE FROM NORMALITY - DISCRIMINANT FUNCTION-ANALYSIS OF FLUORODOPA F-18 POSITRON EMISSION TOMOGRAPHY DATA, ARCHIVES OF NEUROLOGY, Vol: 51, Pages: 237-243, ISSN: 0003-9942

Journal article

BURN DJ, SAWLE GV, BROOKS DJ, 1994, DIFFERENTIAL-DIAGNOSIS OF PARKINSONS-DISEASE, MULTIPLE SYSTEM ATROPHY, AND STEELE-RICHARDSON-OLSZEWSKI SYNDROME - DISCRIMINANT-ANALYSIS OF STRIATAL F-18 DOPA PET DATA, JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vol: 57, Pages: 278-284, ISSN: 0022-3050

Journal article

DEXTER DT, BROOKS DJ, HARDING AE, BURN DJ, MULLER DPR, GOSSSAMPSON MA, JENNER PG, MARSDEN CDet al., 1994, NIGROSTRIATAL FUNCTION IN VITAMIN-E-DEFICIENCY - CLINICAL, EXPERIMENTAL, AND POSITRON EMISSION TOMOGRAPHIC STUDIES, ANNALS OF NEUROLOGY, Vol: 35, Pages: 298-303, ISSN: 0364-5134

Journal article

Perraudeau M, Scott J, Walport M, Oakley C, Bloom S, Brooks Det al., 1994, Late presentation of Kartagener's syndrome. Consequences of ciliary dysfunction., BMJ, Vol: 308, Pages: 519-521, ISSN: 0959-8138

Journal article

Perraudeau M, Scott J, Walport M, Oakley C, Bloom S, Brooks Det al., 1994, Late presentation of Kartagener's syndrome, British Medical Journal, Vol: 308, Pages: 519-521, ISSN: 0959-8146

  • Cite
  • Citations: 10
Journal article

PERRAUDEAU M, WALPORT M, OAKLEY C, BLOOM S, BROOKS Det al., 1994, GRAND ROUNDS - HAMMERSMITH-HOSPITAL - LATE PRESENTATION OF KARTAGENERS-SYNDROME, BMJ-BRITISH MEDICAL JOURNAL, Vol: 308, Pages: 519-521, ISSN: 1756-1833

Journal article

LINDVALL O, SAWLE G, WIDNER H, ROTHWELL JC, BJORKLUND A, BROOKS D, BRUNDIN P, FRACKOWIAK R, MARSDEN CD, ODIN P, REHNCRONA Set al., 1994, EVIDENCE FOR LONG-TERM SURVIVAL AND FUNCTION OF DOPAMINERGIC GRAFTS IN PROGRESSIVE PARKINSONS-DISEASE, ANNALS OF NEUROLOGY, Vol: 35, Pages: 172-180, ISSN: 0364-5134

Journal article

CHAUDHURI KR, EDWARDS R, SAWLE GV, BROOKS DJ, FRACKOWIAK RSJet al., 1994, CARPOPEDAL SPASM AS PRESENTING FEATURE OF ADULT MOYAMOYA DISEASE, CEREBROVASCULAR DISEASES, Vol: 4, Pages: 106-107, ISSN: 1015-9770

Journal article

BLUNT SB, BROOKS DJ, KENNARD C, 1994, STEROID-RESPONSIVE CHOREA IN CHILDHOOD FOLLOWING CARDIAC TRANSPLANTATION, MOVEMENT DISORDERS, Vol: 9, Pages: 112-114, ISSN: 0885-3185

Journal article

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