MrDavidJorgensen

Faculty of Medicine, School of Public Health

Research Assistant

Contact

Location

Building E - Sir Michael UrenWhite City Campus

Summary

I am a PhD student with Professor Nicholas Grassly in the Vaccine Epidemiology Research Group. My current work focuses on the transmission dynamics of wild poliovirus in Pakistan and Afghanistan. This involves the use of bayesian phylogenetic and coalescent methods to infer transmission routes over time using genetic data. The aim of this work is to better incorporate spatially and temporally biased sampling data in estimates of polio transmission dynamics.

I have previously worked on risk assessments for poliovirus transmission in collaboration with the Global Polio Eradication Initiative and the World Health Organization. This work involved mixed effects regression modelling and identifying key high risk areas to target with future vaccination campaigns.

My background is in biology with a masters in Epidemiology and Biostatistics

Publications

Journals

Mourier T, Shuaib M, Hala S, et al.Mourier T, Shuaib M, Hala S, Mfarrej S, Alofi F, Naeem R, Alsomali A, Jorgensen D, Subudhi AK, Ben Rached F, Guan Q, Salunke RP, Ooi A, Esau L, Douvropoulou O, Nugmanova R, Perumal S, Zhang H, Rajan I, Al-Omari A, Salih S, Shamsan A, Al Mutair A, Taha J, Alahmadi A, Khotani N, Alhamss A, Mahmoud A, Alquthami K, Dageeg A, Khogeer A, Hashem AM, Moraga P, Volz E, Almontashiri N, Pain A close, 2022, SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load, Nature Communications, Vol:13, ISSN:2041-1723

Volz E, Mishra S, Chand M, et al.Volz E, Mishra S, Chand M, Barrett JC, Johnson R, Geidelberg L, Hinsley WR, Laydon DJ, Dabrera G, O'Toole Á, Amato R, Ragonnet-Cronin M, Harrison I, Jackson B, Ariani CV, Boyd O, Loman NJ, McCrone JT, Gonçalves S, Jorgensen D, Myers R, Hill V, Jackson DK, Gaythorpe K, Groves N, Sillitoe J, Kwiatkowski DP, COVID-19 Genomics UK (COG-UK) consortium, Flaxman S, Ratmann O, Bhatt S, Hopkins S, Gandy A, Rambaut A, Ferguson NM close, 2021, Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England, Nature, Vol:593, ISSN:0028-0836, Pages:266-269

Ragonnet-Cronin M, Boyd O, Geidelberg L, et al.Ragonnet-Cronin M, Boyd O, Geidelberg L, Jorgensen D, Nascimento F, Siveroni I, Johnson R, Baguelin M, Cucunuba Z, Jauneikaite E, Mishra S, Watson O, Ferguson N, Cori A, Donnelly C, Volz E close, 2021, Genetic evidence for the association between COVID-19 epidemic severity and timing of non-pharmaceutical interventions, Nature Communications, Vol:12, ISSN:2041-1723, Pages:1-7

Volz E, Hill V, McCrone J, et al.Volz E, Hill V, McCrone J, Price A, Jorgensen D, O'Toole A, Southgate JA, Johnson R, Jackson B, Nascimento F, Rey S, Nicholls S, Colquhoun R, da Silva Filipe A, Shepherd J, Pascall D, Shah R, Jesudason N, Li K, Jarrett R, Pacchiarini N, Bull M, Geidelberg L, Siveroni I, Goodfellow I, Loman NJ, Pybus O, Robertson D, Thomson E, Rambaut A, Connor T, The COVID-19 Genomics UK Consortium close, 2021, Evaluating the effects of SARS-CoV-2 Spike mutation D614G on transmissibility and pathogenicity, Cell, Vol:184, ISSN:0092-8674, Pages:64-75.e11

Geidelberg L, Boyd O, Jorgensen D, et al.Geidelberg L, Boyd O, Jorgensen D, Siveroni I, Nascimento FF, Johnson R, Ragonnet-Cronin M, Fu H, Wang H, Xi X, Chen W, Liu D, Chen Y, Tian M, Tan W, Zai J, Sun W, Li J, Li J, Volz E, Li X, Nie Q close, 2021, Genomic epidemiology of a densely sampled COVID-19 outbreak in China, Virus Evolution, Vol:7, ISSN:2057-1577, Pages:1-7

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