Professor David Sharp is a neurologist and Centre Director of UK DRI Care Research & Technology, focusing on using technology to enhance the lives of people living with dementia. He is also Scientific Director of the Imperial College Clinical Imaging Facility and Associate Director of the Imperial Centre for Injury Studies. His research programme aims to improve clinical outcomes after dementia and traumatic brain injury (TBI), focusing on common cognitive impairments in domains such as memory and attention. He uses cognitive neuroscience and advanced neuroimaging to investigate the effect of brain injury on brain network function and the effects of inflammation and neurodegeneration. His has explored how new treatments of cognitive impairment can be personalised and his current work focuses on harnessing neurotechnology development to improve the lives of those living with dementia and the effects of brain injury.
et al., 2020, Diffusion tensor imaging of lumbar spinal nerves reveals changes in microstructural integrity following decompression surgery associated with improvements in clinical symptoms: A case report., Magn Reson Imaging
et al., Distinct patterns of structural damage underlie working memory and reasoning deficits after traumatic brain injury, Brain: a Journal of Neurology, ISSN:0006-8950
et al., Distinct dopaminergic abnormalities in traumatic brain injury and Parkinson’s disease, Journal of Neurology, Neurosurgery and Psychiatry, ISSN:0022-3050
et al., 2019, Cognitive function and drivers of cognitive impairment in a European and a Korean cohort of people living with HIV, International Journal of Std & Aids, Vol:31, ISSN:0956-4624, Pages:30-37
Graham NSN, Sharp DJ, 2019, Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia, Journal of Neurology, Neurosurgery & Psychiatry, Vol:90, ISSN:0022-3050