ProfessorDavidSharp

Faculty of Medicine, Department of Brain Sciences

Professor of Neurology

Contact

+44 (0)20 7594 7991david.sharp Website

Assistant

Professor Nick Oliver +44 (0)20 7594 1796

Location

E315B - C3NLBurlington DanesHammersmith Campus

Summary

Professor David Sharp is a neurologist and Centre Director of UK DRI Care Research & Technology, focusing on using technology to enhance the lives of people living with dementia. He is also Scientific Director of the Imperial College Clinical Imaging Facility and Associate Director of the Imperial Centre for Injury Studies. His research programme aims to improve clinical outcomes after dementia and traumatic brain injury (TBI), focusing on common cognitive impairments in domains such as memory and attention. He uses cognitive neuroscience and advanced neuroimaging to investigate the effect of brain injury on brain network function and the effects of inflammation and neurodegeneration. His has explored how new treatments of cognitive impairment can be personalised and his current work focuses on harnessing neurotechnology development to improve the lives of those living with dementia and the effects of brain injury.

Publications

Journals

Hughes SH, Hellyer PJ, Sharp DJ, et al.Hughes SH, Hellyer PJ, Sharp DJ, Newbould RD, Patel MC, Strutton PH close, 2020, Diffusion tensor imaging of lumbar spinal nerves reveals changes in microstructural integrity following decompression surgery associated with improvements in clinical symptoms: A case report., Magn Reson Imaging

Jolly A, Scott G, Sharp D, et al.Jolly A, Scott G, Sharp D, Hampshire A close, Distinct patterns of structural damage underlie working memory and reasoning deficits after traumatic brain injury, Brain: a Journal of Neurology, ISSN:0006-8950

Open Access Link

Jenkins P, Roussakis A-A, De Simoni S, et al.Jenkins P, Roussakis A-A, De Simoni S, Bourke N, Fleminger J, Cole J, Piccini P, Sharp D close, Distinct dopaminergic abnormalities in traumatic brain injury and Parkinson’s disease, Journal of Neurology, Neurosurgery and Psychiatry, ISSN:0022-3050

Open Access Link

De Francesco D, Choi J-P, Choi JY, et al.De Francesco D, Choi J-P, Choi JY, van Zoest RA, Underwood J, Schouten J, Ku NS, Kim WJ, Reiss P, Sabin CA, Winston A, Reiss P, Winston A, Wit FW, Prins M, van der Loeff MFS, Schouten J, Schmand B, Geurtsen GJ, Sharp DJ, Caan MWA, Majoie C, Villaudy J, Berkhout B, Kootstra NA, Gisslen M, Pasternak A, Sabin CA, Guaraldi G, Burkle A, Libert C, Franceschi C, Kalsbeek A, Fliers E, Hoeijmakers J, Pothof J, van der Valk M, Bisschop PH, Portegies P, Zaheri S, Burger D, Reiss P, Winston A, Wit FW, Cole JH, Caan MWA, Villaudy J, Kootstra NA, van der Loeff MFS, Gisslen M, Sabin CA, Burkle A, Zikkenheiner W, Reiss P, Zikkenheiner W, Wit FW, Janssen FR, Winston A, Wit FW, Underwood J, Schouten J, Kooij KW, van Zoest RA, Doyle N, Prins M, van der Loeff MS, Portegies P, Schmand BA, Geurtsen GJ, Verheij E, Verboeket SO, Elsenga BC, van der Valk M, Zaheri S, Hillebregt MMJ, Ruijs YMC, Benschop DP, Tembo L, McDonald L, Stott M, Legg K, Lovell A, Erlwein O, Kingsley C, Norsworthy P, Mullaney S, Kruijer T, del Grande L, Olthof V, Visser GR, May L, Verbraak F, Demirkaya N, Visser I, Guaraldi G, Sharp DJ, Caan MWA, Cole JH, Majoie CBLM, Su T, Leech R, Huguet J, Villaudy J, Frankin E, Pasternak A, Berkhout B, van der Kuyl A, Weijer K, Siteur-Van Rijnstra E, Kootstra NA, Gisslen M, Harskamp-Holwerda AM, Maurer I, Ruiz MMM, Girigorie AF, Boeser-Nunnink B, Kalsbeek A, Bisschop PHLT, Burger D, de Graaff-Teulen M, Hoeijmakers J, Pothof J, Libert C, Dewaele S, Franceschi C, Garagnani P, Pirazzini C, Capri M, Dall'Olio F, Chiricolo M, Salvioli S, Fuchs D, Zetterberg H, Weber D, Grune T, Jansen EHJM, Sabin CA, De Francesco D, Wit FW, Burkle A, Sindlinger T, Oehlke S, Zikkenheiner W, van Zoest RA close, 2019, Cognitive function and drivers of cognitive impairment in a European and a Korean cohort of people living with HIV, International Journal of Std & Aids, Vol:31, ISSN:0956-4624, Pages:30-37

Graham NSN, Sharp DJ, 2019, Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia, Journal of Neurology, Neurosurgery & Psychiatry, Vol:90, ISSN:0022-3050

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