Summary
David Sharp is an NIHR Research Professor and honorary consultant neurologist with a special interest in traumatic brain injury. He runs a multidisciplinary traumatic brain injury clinic at Charing Cross hospital and directs a program of research investigating the impact of traumatic brain injury on cognitive function. His research uses advanced neuroimaging to study brain network function, both in healthy individuals and following brain injury. By understanding changes in network function he hopes to guide the development of novel treatment strategies for patients with cognitive impairment following brain injury.
Publications
Journals
Sridharan S, Raffel J, Nandoskar A, et al., 2019, Confirmation of specific binding of the 18 kDa translocator protein (TSPO) radioligand [18F]GE-180: a blocking study using XBD173 in multiple sclerosis normal appearing white and grey matter, Molecular Imaging and Biology, Vol:21, ISSN:1536-1632, Pages:935-944
Graham NSN, Sharp DJ, 2019, Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia, Journal of Neurology, Neurosurgery & Psychiatry, ISSN:0022-3050
Gorgoraptis N, Li LM, Whittington A, et al., 2019, In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury, Science Translational Medicine, Vol:11, ISSN:1946-6234, Pages:1-14
Li L, Violante I, Zimmerman K, et al., Traumatic axonal injury influences the cognitive effect of non-invasive brain stimulation, Brain, ISSN:1460-2156
Jolly AE, Raymont V, Cole JH, et al., 2019, Dopamine D2/D3 receptor abnormalities after traumatic brain injury and their relationship to post-traumatic depression, Neuroimage: Clinical, Vol:24, ISSN:2213-1582