Imperial College London
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ProfessorDavidSharp

Faculty of Medicine, Department of Brain Sciences

Professor of Neurology
 
 
 
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Contact

 

+44 (0)20 7594 7991david.sharp Website

 
 
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Location

 

UREN.927Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Gil:2022:10.1016/j.bios.2022.114050,
author = {Gil, Rosa B and Akingbade, OE and Guo, X and Gonzalez-Macia, L and Crone, MA and Cameron, LP and Freemont, P and Choy, K-L and Güder, F and Yeatman, E and Sharp, DJ and Li, B},
doi = {10.1016/j.bios.2022.114050},
journal = {Biosensors and Bioelectronics},
title = {Multiplexed immunosensors for point-of-care diagnostic applications},
url = {http://dx.doi.org/10.1016/j.bios.2022.114050},
volume = {203},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Accurate, reliable, and cost-effective immunosensors are clinically important for the early diagnosis and monitoring of progressive diseases, and multiplexed sensing is a promising strategy for the next generation of diagnostics. This strategy allows for the simultaneous detection and quantification of multiple biomarkers with significantly enhanced reproducibility and reliability, whilst requiring smaller sample volumes, fewer materials, and shorter average analysis time for individual biomarkers than individual tests. In this opinionated review, we compare different techniques for the development of multiplexed immunosensors. We review the state-of-the-art approaches in the field of multiplexed immunosensors using electrical, electrochemical, and optical methods. The barriers that prevent translating this sensing strategy into clinics are outlined together with the potential solutions. We also share our vision on how multiplexed immunosensors will continue their evolution in the coming years.
AU  - Gil,Rosa B
AU  - Akingbade,OE
AU  - Guo,X
AU  - Gonzalez-Macia,L
AU  - Crone,MA
AU  - Cameron,LP
AU  - Freemont,P
AU  - Choy,K-L
AU  - Güder,F
AU  - Yeatman,E
AU  - Sharp,DJ
AU  - Li,B
DO  - 10.1016/j.bios.2022.114050
PY  - 2022///
SN  - 0956-5663
TI  - Multiplexed immunosensors for point-of-care diagnostic applications
T2  - Biosensors and Bioelectronics
UR  - http://dx.doi.org/10.1016/j.bios.2022.114050
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35134685
UR  - http://hdl.handle.net/10044/1/94931
VL  - 203
ER  -
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