I am a graduate of the Cambridge MB/PhD programme. Originally studying immune tolerance breakdown in type 1 diabetes with Anne Cooke for my PhD, I then worked as a Clinical Lecturer with Ken Smith and Gordon Dougan FRS. During this time, I characterised the novel protein EROS. Having demonstrated that EROS was essential for the generation of reactive oxygen species by the innate immune system, I was awarded a Wellcome Trust Clinical Research Career Development Fellowship and the Beit Prize in 2017. In April 2019, I moved my laboratory to Imperial College to take up a Readership. My laboratory works on (i) how Eros controls the phagocyte respiratory burst and other processes in innate and adaptive immunity as well as (ii) the role of reactive oxygen species, derived from a variety of sources, in immunity more generally. My clinical work is as a nephrologist and internal physician and I am a Consultant Nephrologist at the Hammersmith Hospital, predominantly focused on the care of renal transplant patients.
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