Selected Publications
Journal Articles
Rajab MD, Jammeh E, Taketa T, et al.Rajab MD, Jammeh E, Taketa T, Brayne C, Matthews FE, Su L, Ince PG, Wharton SB, Wang D close, 2022, Assessment of Alzheimer-related Pathologies of Dementia Using Machine Learning Feature Selection
Kariotis S, Jammeh E, Swietlik EM, et al.Kariotis S, Jammeh E, Swietlik EM, Pickworth JA, Rhodes CJ, Otero P, Wharton J, Iremonger J, Dunning MJ, Pandya D, Mascarenhas TS, Errington N, Thompson AAR, Romanoski CE, Rischard F, Garcia JGN, Yuan JX-J, An T-HS, Desai AA, Coghlan G, Lordan J, Corris PA, Howard LS, Condliffe R, Kiely DG, Church C, Pepke-Zaba J, Toshner M, Wort S, Graf S, Morrell NW, Wilkins MR, Lawrie A, Wang D, Bleda M, Bleda M, Hadinnapola C, Haimel M, Auckland K, Tilly T, Martin JM, Yates K, Treacy CM, Day M, Greenhalgh A, Shipley D, Peacock AJ, Irvine V, Kennedy F, Moledina S, MacDonald L, Tamvaki E, Barnes A, Cookson V, Chentouf L, Ali S, Othman S, Ranganathan L, Gibbs JSR, DaCosta R, Pinguel J, Dormand N, Parker A, Stokes D, Ghedia D, Tan Y, Ngcozana T, Wanjiku I, Polwarth G, Mackenzie Ross RV, Suntharalingam J, Grover M, Kirby A, Grove A, White K, Seatter A, Creaser-Myers A, Walker S, Roney S, Elliot CA, Charalampopoulos A, Sabroe I, Hameed A, Armstrong I, Hamilton N, Rothman AMK, Swift AJ, Wild JM, Soubrier F, Eyries M, Humbert M, Montani D, Girerd B, Scelsi L, Ghio S, Gall H, Ghofrani A, Bogaard HJ, Noordegraaf AV, Houweling AC, Veld AHI, Schotte G close, 2021, Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood, Nature Communications, Vol:12, ISSN:2041-1723, Pages:1-14
Errington N, Iremonger J, Pickworth JA, et al.Errington N, Iremonger J, Pickworth JA, Kariotis S, Rhodes CJ, Rothman AM, Condliffe R, Elliot CA, Kiely DG, Howard LS, Wharton J, Thompson AAR, Morrell NW, Wilkins MR, Wang D, Lawrie A close, 2021, A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach, Ebiomedicine, Vol:69, ISSN:2352-3964
Shepheard SR, Parker MD, Cooper-Knock J, et al.Shepheard SR, Parker MD, Cooper-Knock J, Verber NS, Tuddenham L, Heath P, Beauchamp N, Place E, Sollars ESA, Turner MR, Malaspina A, Fratta P, Hewamadduma C, Jenkins TM, McDermott CJ, Wang D, Kirby J, Shaw PJ close, 2021, Value of systematic genetic screening of patients with amyotrophic lateral sclerosis, Journal of Neurology Neurosurgery and Psychiatry, Vol:92, ISSN:0022-3050, Pages:510-518
Parker MD, Lindsey BB, Leary S, et al.Parker MD, Lindsey BB, Leary S, Gaudieri S, Chopra A, Wyles M, Angyal A, Green LR, Parsons P, Tucker RM, Brown R, Groves D, Johnson K, Carrilero L, Heffer J, Patridge DG, Evans C, Raza M, Keeley AJ, Smith N, Filipe ADS, Shepherd JG, Davis C, Bennett S, Sreenu VB, Kohl A, Aranday-Cortes E, Tong L, Nichols J, Thomson EC, Wang D, Mallal S, de Silva TI close, 2021, Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data, Genome Research, Vol:31, ISSN:1088-9051, Pages:645-658
Wang D, Hensman J, Kutkaite G, et al.Wang D, Hensman J, Kutkaite G, Toh TS, Galhoz A, Dry JR, Saez-Rodriguez J, Garnett MJ, Menden MP, Dondelinger F close, 2020, A statistical framework for assessing pharmacological responses and biomarkers using uncertainty estimates, Elife, Vol:9, ISSN:2050-084X
Rhodes C, Otero-Núñez P, Wharton J, et al.Rhodes C, Otero-Núñez P, Wharton J, Swietlik E, Kariotis S, Harbaum L, Dunning M, Elinoff J, Errington N, Roger T, Iremonger J, Coghlan G, Corris P, Howard L, Kiely D, Church C, Pepke-Zaba J, Toshner M, Stephen W, Desai A, Humbert M, Nichols W, Southgate L, Tregouet D-A, Trembath R, Prokopenko I, Graf S, Morrell N, Wang D, Lawrie A, Wilkins M close, 2020, Whole blood RNA profiles associated with pulmonary arterial hypertension and clinical outcome, American Journal of Respiratory and Critical Care Medicine, Vol:202, ISSN:1073-449X, Pages:586-594
Freeman TM, Wang D, Harris J, et al.Freeman TM, Wang D, Harris J, Ambrose JC, Arumugam P, Baple EL, Bleda M, Boardman-Pretty F, Boissiere JM, Boustred CR, Caulfield MJ, Chan GC, Craig CEH, Daugherty LC, de Burca A, Devereau A, Elgar G, Foulger RE, Fowler T, Furio-Tari P, Hackett JM, Halai D, Hamblin A, Henderson S, Holman JE, Hubbard TJP, Ibanez K, Jackson R, Jones LJ, Kasperaviciute D, Kayikci M, Lahnstein L, Lawson K, Leigh SEA, Leong IUS, Lopez JF, Maleady-Crowe F, Mason J, McDonagh EM, Moutsianas L, Mueller M, Murugaesu N, Need AC, Odhams CA, Patch C, Perez-Gil D, Polychronopoulos D, Pullinger J, Rahim T, Rendon A, Riesgo-Ferreiro P, Rogers T, Ryten M, Savage K, Sawant K, Scott RH, Siddiq A, Sieghart A, Smedley D, Smith KR, Sosinsky A, Spooner W, Stevens HE, Stuckey A, Sultana R, Thomas ERA, Thompson SR, Tregidgo C, Tucci A, Walsh E, Watters SA, Welland MJ, Williams E, Witkowska K, Wood SM, Zarowiecki M close, 2020, Genomic loci susceptible to systematic sequencing bias in clinical whole genomes, Genome Research, Vol:30, ISSN:1088-9051, Pages:415-426
Wharton SB, Wang D, Parikh C, et al.Wharton SB, Wang D, Parikh C, Matthews FE, Brayne C, Ince PG close, 2019, Epidemiological pathology of A beta deposition in the ageing brain in CFAS: addition of multiple A beta-derived measures does not improve dementia assessment using logistic regression and machine learning approaches, Acta Neuropathologica Communications, Vol:7, ISSN:2051-5960
Keshava N, Toh TS, Yuan H, et al.Keshava N, Toh TS, Yuan H, Yang B, Menden MP, Wang D close, 2019, Defining subpopulations of differential drug response to reveal novel target populations, Npj Systems Biology and Applications, Vol:5
Toh TS, Dondelinger F, Wang D, 2019, Looking beyond the hype: Applied AI and machine learning in translational medicine, Ebiomedicine, Vol:47, ISSN:2352-3964, Pages:607-615
Wang D, Nhu-An P, Freeman TM, et al.Wang D, Nhu-An P, Freeman TM, Raghavan V, Navab R, Chang J, Zhu C-Q, Ly D, Tong J, Wouters BG, Pintilie M, Moran MF, Liu G, Shepherd FA, Tsao M-S close, 2019, Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer, Cancers, Vol:11
Menden MP, Wang D, Mason MJ, et al.Menden MP, Wang D, Mason MJ, Szalai B, Bulusu KC, Guan Y, Yu T, Kang J, Jeon M, Wolfinger R, Nguyen T, Zaslavskiy M, Jang IS, Ghazoui Z, Ahsen ME, Vogel R, Neto EC, Norman T, Tang EKY, Garnett MJ, Di Veroli GY, Fawell S, Stolovitzky G, Guinney J, Dry JR, Saez-Rodriguez J, Abante J, Abecassis BS, Aben N, Aghamirzaie D, Aittokallio T, Akhtari FS, Al-lazikani B, Alam T, Allam A, Allen C, de Almeida MP, Altarawy D, Alves V, Amadoz A, Anchang B, Antolin AA, Ash JR, Romeo Aznar V, Ba-alawi W, Bagheri M, Bajic V, Ball G, Ballester PJ, Baptista D, Bare C, Bateson M, Bender A, Bertrand D, Wijayawardena B, Boroevich KA, Bosdriesz E, Bougouffa S, Bounova G, Brouwer T, Bryant B, Calaza M, Calderone A, Calza S, Capuzzi S, Carbonell-Caballero J, Carlin D, Carter H, Castagnoli L, Celebi R, Cesareni G, Chang H, Chen G, Chen H, Chen H, Cheng L, Chernomoretz A, Chicco D, Cho K-H, Cho S, Choi D, Choi J, Choi K, Choi M, De Cock M, Coker E, Cortes-Ciriano I, Cserzo M, Cubuk C, Curtis C, Van Daele D, Dang CC, Dijkstra T, Dopazo J, Draghici S, Drosou A, Dumontier M, Ehrhart F, Eid F-E, ElHefnawi M, Elmarakeby H, van Engelen B, Engin HB, de Esch I, Evelo C, Falcao AO, Farag S, Fernandez-Lozano C, Fisch K, Flobak A, Fornari C, Foroushani ABK, Fotso DC, Fourches D, Friend S, Frigessi A, Gao F, Gao X, Gerold JM, Gestraud P, Ghosh S, Gillberg J, Godoy-Lorite A, Godynyuk L, Godzik A, Goldenberg A, Gomez-Cabrero D, Gonen M, de Graaf C, Gray H, Grechkin M, Guimera R, Guney E, Haibe-Kains B, Han Y, Hase T, He D, He L, Heath LS, Hellton KH, Helmer-Citterich M, Hidalgo MR, Hidru D, Hill SM, Hochreiter S, Hong S, Hovig E, Hsueh Y-C, Hu Z, Huang JK, Huang RS, Hunyady L, Hwang J, Hwang TH, Hwang W, Hwang Y, Isayev O, Walk OBD, Jack J, Jahandideh S, Ji J, Jo Y, Kamola PJ, Kanev GK, Karacosta L, Karimi M, Kaski S, Kazanov M, Khamis AM, Khan SA, Kiani NA, Kim A, Kim J, Kim J, Kim K, Kim K, Kim S, Kim Y, Kim Y, Kirk PDW, Kitano H, Klambauer G, Knowles D, Ko M, Kohn-Luque A, Kooistra AJ, Kuenemann MA, Kuiper M, Kurz C, Kwon M, van Laarhoven T, Laegreid A, Lederer S, Lee H, Lee J, Lee YW, Leppaho E, Lewis R, Li J, Li L, Liley J, Lim WK, Lin C, Liu Y, Lopez Y, Low J, Lysenko A, Machado D, Madhukar N, De Maeyer D, Malpartida AB, Mamitsuka H, Marabita F, Marchal K, Marttinen P, Mason D, Mazaheri A, Mehmood A, Mehreen A, Michaut M, Miller RA, Mitsopoulos C, Modos D, Van Moerbeke M, Moo K, Motsinger-Reif A, Movva R, Muraru S, Muratov E, Mushthofa M, Nagarajan N, Nakken S, Nath A, Neuvial P, Newton R, Ning Z, De Niz C, Oliva B, Olsen C, Palmeri A, Panesar B, Papadopoulos S, Park J, Park S, Park S, Pawitan Y, Peluso D, Pendyala S, Peng J, Perfetto L, Pirro S, Plevritis S, Politi R, Poon H, Porta E, Prellner I, Preuer K, Angel Pujana M, Ramnarine R, Reid JE, Reyal F, Richardson S, Ricketts C, Rieswijk L, Rocha M, Rodriguez-Gonzalvez C, Roell K, Rotroff D, de Ruiter JR, Rukawa P, Sadacca B, Safikhani Z, Safitri F, Sales-Pardo M, Sauer S, Schlichting M, Seoane JA, Serra J, Shang M-M, Sharma A, Sharma H, Shen Y, Shiga M, Shin M, Shkedy Z, Shopsowitz K, Sinai S, Skola D, Smirnov P, Soerensen IF, Soerensen P, Song J-H, Song SO, Soufan O, Spitzmueller A, Steipe B, Suphavilai C, Tamayo SP, Tamborero D, Tang J, Tanoli Z-U-R, Tarres-Deulofeu M, Tegner J, Thommesen L, Tonekaboni SAM, Tran H, De Troyer E, Truong A, Tsunoda T, Turu G, Tzeng G-Y, Verbeke L, Videla S, Vis D, Voronkov A, Votis K, Wang A, Wang H-QH, Wang P-W, Wang S, Wang W, Wang X, Wang X, Wennerberg K, Wernisch L, Wessels L, van Westen GJP, Westerman BA, White SR, Willighagen E, Wurdinger T, Xie L, Xie S, Xu H, Yadav B, Yau C, Yeerna H, Yin JW, Yu M, Yu M, Yun SJ, Zakharov A, Zamichos A, Zanin M, Zeng L, Zenil H, Zhang F, Zhang P, Zhang W, Zhao H, Zhao L, Zheng W, Zoufir A, Zucknick M close, 2019, Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen, Nature Communications, Vol:10, ISSN:2041-1723
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