Summary
I am an Advanced Clinical Research Fellow, specialising in leveraging human genetic data to help unravel cardiometabolic disease mechanisms and offer insight into therapeutic opportunities. Concurrently, I am the Lead for Integrated Omics at the Health Analytics section of Lane Clark & Peacock (LCP). My background is as a Clinical Pharmacologist and General Internal Physician, with more than 11 years of experience within the National Health Service, a Genetic Epidemiologist with more than 200 publications, and as an expert at optimising the integration of human-centric evidence to inform drug development, with more than 3 years of experience in this capacity at the pharmaceutical company Novo Nordisk.
My role at LCP is to lead a multi-disciplinary team focused on leveraging multi-omics data, including genomics, metabolomics, and proteomics, to unravel disease mechanisms, inform drug development efforts, and study the effects of healthcare interventions. My combined expertise in medicine, genetic epidemiology and drug development uniquely positions me as a leading authority on the applications of omics data for generating clinically translatable insights.
I am currently on the Editorial Board of BMJ Medicine, serve as an Editorial Advisor at BMC Medicine, and remain active in research with an H-index of 39, contributing to several international genetic consortia, including the International Stroke Genetics Consortium and the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE).
Publications
Journals
Dib M-J, Zagkos L, Meena D, et al., 2024, LDL-c Lowering, Ischemic Stroke, and Small Vessel Disease Brain Imaging Biomarkers: A Mendelian Randomization Study., Stroke
Au Yeung SL, Gill D, 2024, Concerns over using the Mendelian randomization design to investigate the effect of air pollution., Sci Total Environ, Vol:917
Woolf B, Perry JA, Hong CC, et al., 2024, Multi-biobank summary data Mendelian randomisation does not support a causal effect of IL-6 signalling on risk of pulmonary arterial hypertension., Eur Respir J
Dib M-J, Levin MG, Zhao L, et al., 2024, Proteomic Associations of Adverse Outcomes in Human Heart Failure., J Am Heart Assoc, Vol:13
Yuan S, Xu F, Zhang H, et al., 2024, Proteomic insights into modifiable risk of venous thromboembolism and cardiovascular comorbidities., J Thromb Haemost, Vol:22, Pages:738-748