Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Chair in Gene Therapy



+44 (0)20 7594 7929e.alton




Miss Samia Soussi +44 (0)20 7594 7980




Emmanuel Kaye BuildingRoyal Brompton Campus





Eric Alton is Professor of Gene Therapy and Respiratory Medicine, National Heart & Lung Institute, Imperial College London and Honorary Consultant Physician, Royal Brompton Hospital

Professor Alton was educated at Jesus College, Cambridge and Westminster Medical School and subsequently undertook six years of general medical training.  Over the last fifteen years, he has been involved in developing gene therapy for cystic fibrosis and angiogenesis, including three clinical trials.

Professor Alton coordinates the UK CF Gene Therapy Consortium which brings together the three centres in the UK (Edinburgh and Oxford Universities and Imperial College), including approximately 80 clinicians and scientists focused on this problem.




Taylor-Cousar JL, Boyd AC, Alton EWFW, et al., 2023, Genetic therapies in cystic fibrosis, Current Opinion in Pulmonary Medicine, Vol:29, ISSN:1070-5287, Pages:615-620

Edmondson C, Westrupp N, Short C, et al., 2023, Unsupervised home spirometry is not equivalent to supervised clinic spirometry in children and young people with cystic fibrosis: results from the CLIMB-CF study, Pediatric Pulmonology, Vol:58, ISSN:1099-0496, Pages:2871-2880

Davies J, Morales S, Alton E, et al., 2023, Lytic bacteriophage is a promising adjunct to common antibiotics across cystic fibrosis clinical strains and culture models of Pseudomonas aeruginosa infection, Antibiotics, Vol:12, ISSN:2079-6382, Pages:1-14


Miah KM, Chan M, Griesenbach U, et al., 2023, Novel Buffer Formulations for Improved Recombinant Lentiviral Vector Stability and <i>In Vivo</i> Delivery to the Murine Lungs, CELL PRESS, Pages:760-760, ISSN:1525-0016

Bell RV, Clarke NK, Alton EWFW, et al., 2022, Regulated expression of secreted transgenes by pulmonary transplanted macrophages in mice, 29th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy (ESCGT), MARY ANN LIEBERT, INC, Pages:A55-A55, ISSN:1043-0342

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