Summary
Eric Alton is Professor of Gene Therapy and Respiratory Medicine, National Heart & Lung Institute, Imperial College London and Honorary Consultant Physician, Royal Brompton Hospital
Professor Alton was educated at Jesus College, Cambridge and Westminster Medical School and subsequently undertook six years of general medical training. Over the last fifteen years, he has been involved in developing gene therapy for cystic fibrosis and angiogenesis, including three clinical trials.
Professor Alton coordinates the UK CF Gene Therapy Consortium which brings together the three centres in the UK (Edinburgh and Oxford Universities and Imperial College), including approximately 80 clinicians and scientists focused on this problem.
Publications
Journals
Coates M, Alton E, Rapeport W, et al., 2021, Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway, Plos One, ISSN:1932-6203
Conference
Alton EW, Boyd A, Davies JC, et al., 2020, TOWARDS A FIRST-IN-HUMAN TRIAL WITH A PSEUDOTYPED LENTIVIRUS, WILEY, Pages:S224-S224, ISSN:8755-6863
Sergijenko A, Moiseenko A, Pineault KM, et al., 2020, LOW LEVELS OF CFTR GENE TRANSFER WITH F/HN PSEUDOTYPED LENTIVIRUS ARE SUFFICIENT TO GENERATE ION TRANSPORT CORRECTION IN AIRWAY CELL CULTURES FROM CYSTIC FIBROSIS PATIENTS, WILEY, Pages:S73-S73, ISSN:8755-6863
Pineault KM, Meng C, Griesenbach U, et al., 2020, BIODISTRIBUTION AND ENVIRONMENTAL SHEDDING OF LENTIVIRAL VECTORS FOLLOWING TOPICAL ADMINISTRATION TO MURINE LUNGS, WILEY, Pages:S240-S240, ISSN:8755-6863
Edmondson C, Westrupp N, Wallenburg J, et al., 2020, MONITORING LUNG FUNCTION OF YOUNG PEOPLE WITH CF AT HOME: IS IT RELIABLE? RESULTS FROM THE CLIMB-CF STUDY, WILEY, Pages:S290-S290, ISSN:8755-6863