Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Chair in Gene Therapy



+44 (0)20 7594 7937e.alton




Miss Samia Soussi +44 (0)20 7594 7980




Emmanuel Kaye BuildingRoyal Brompton Campus





Eric Alton is Professor of Gene Therapy and Respiratory Medicine, National Heart & Lung Institute, Imperial College London and Honorary Consultant Physician, Royal Brompton Hospital

Professor Alton was educated at Jesus College, Cambridge and Westminster Medical School and subsequently undertook six years of general medical training.  Over the last fifteen years, he has been involved in developing gene therapy for cystic fibrosis and angiogenesis, including three clinical trials.

Professor Alton coordinates the UK CF Gene Therapy Consortium which brings together the three centres in the UK (Edinburgh and Oxford Universities and Imperial College), including approximately 80 clinicians and scientists focused on this problem.




McLachlan G, Alton EWFW, Boyd AC, et al., 2022, Progress in Respiratory Gene Therapy, Human Gene Therapy, Vol:33, ISSN:1043-0342, Pages:893-912

Alton E, Lund-Palau H, Juarez-Molina C, et al., 2022, Correction of a chronic pulmonary disease through lentiviral vector-mediated protein expression, Molecular Therapy - Methods and Clinical Development, Vol:25, ISSN:2329-0501, Pages:382-391


Bell R, Clarke NK, Isalan M, et al., Regulated Expression of LentiviralVectors Following Administration of anInducing Molecule, 2022 ASGCT Annual Meeting, Cell Press, Pages:419-419, ISSN:1525-0016

Clarke NK, Sergijenko A, Pineault K, et al., 2022, Ex Vivo Transduced Macrophages Engraft in the Lung Following Transplantation and Produce Therapeutic Levels of Secreted Proteins, American Society of Cell and Gene Therapy, CELL PRESS, Pages:405-405, ISSN:1525-0016

Bell RV, Clarke NK, Isalan M, et al., 2022, Regulated Expression of Lentiviral Vectors Following Administration of an Inducing Molecule, CELL PRESS, Pages:419-419, ISSN:1525-0016

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