Imperial College London

ProfessorEricAlton

Faculty of MedicineNational Heart & Lung Institute

Chair in Gene Therapy
 
 
 
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Contact

 

+44 (0)20 7594 7937e.alton

 
 
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Location

 

Emmanuel Kaye BuildingRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

358 results found

Thursfield RM, Naderi K, Leaver N, Rosenthal M, Alton EWFW, Bush A, Davies JCet al., 2018, Children with cystic fibrosis demonstrate no respiratory immunological, infective or physiological, consequences of vitamin D deficiency, JOURNAL OF CYSTIC FIBROSIS, Vol: 17, Pages: 657-665, ISSN: 1569-1993

JOURNAL ARTICLE

Paul-Smith MC, Pytel KM, Gelinas J-F, McIntosh J, Pringle I, Davies L, Chan M, Meng C, Bell R, Cammack L, Moran C, Cameron L, Inoue M, Tsugumine S, Hironaka T, Gill DR, Hyde SC, Nathwani A, Alton EWFW, Griesenbach Uet al., 2018, The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins, GENE THERAPY, Vol: 25, Pages: 345-358, ISSN: 0969-7128

JOURNAL ARTICLE

Bardin EE, Cameron SJS, Perdones-Montero A, Hardiman K, Bolt F, Alton EWFW, Bush A, Davies JC, Takats Zet al., 2018, Metabolic Phenotyping and Strain Characterisation of Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients Using Rapid Evaporative Ionisation Mass Spectrometry, SCIENTIFIC REPORTS, Vol: 8, ISSN: 2045-2322

JOURNAL ARTICLE

Clarke N, Saleh A, Meng C, Griesenbach U, Alton Eet al., 2018, Validation of a PCR-based assay to quantify lentiviral vector shedding in human body fluids, Annual Conference of the British-Society-for-Gene-and-Cell-Therapy, Publisher: MARY ANN LIEBERT, INC, Pages: A11-A11, ISSN: 1043-0342

CONFERENCE PAPER

Saleh A, Meng C, Chan M, Alton EWFW, Griesenbach Uet al., 2018, RNA in-situ hybridisation is able to quantify lentiviral transduction of respiratory epithelium, Annual Conference of the British-Society-for-Gene-and-Cell-Therapy, Publisher: MARY ANN LIEBERT, INC, Pages: A7-A7, ISSN: 1043-0342

CONFERENCE PAPER

Lund-Palau H, Pilou A, Atsumi N, Pringle I, Ashworth RC, Meng C, Chan M, Gill D, Hyde S, Morgan C, Alton EWFW, Griesenbach Uet al., 2018, Lentivirus GM-CSF gene therapy for autoimmune pulmonary alveolar proteinosis, Annual Conference of the British-Society-for-Gene-and-Cell-Therapy, Publisher: MARY ANN LIEBERT, INC, Pages: A2-A2, ISSN: 1043-0342

CONFERENCE PAPER

Turnbull AR, Murphy R, Behrends V, Lund-Palau H, Simbo A, Mariveles M, Alton EWFW, Bush A, Shoemark A, Davies JCet al., 2018, Impact of T2R38 Receptor Polymorphisms on Pseudomonas aeruginosa Infection in Cystic Fibrosis, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 197, Pages: 1635-1638, ISSN: 1073-449X

JOURNAL ARTICLE

Shovlin CL, Nur F, St Prix MS, Redhead J, Alton EA, Bernabeu-Herrero ME, Fowler T, Caulfield M, Thomas E, Boardman-Pretty F, McDonagh E, Devereau A, Scott Ret al., 2018, Hereditary haemorrhagic telangiectasia and the 100,000 genomes project, Publisher: SPRINGER, Pages: 125-125, ISSN: 0969-6970

CONFERENCE PAPER

Edmondson C, Murphy R, Moffitt K, Ribeiro D, Alton EWFW, Davies JCet al., 2017, IT IS POSSIBLE TO DETECT ACTIVE NEUTROPHIL ELASTASE IN EXHALED BREATH CONDENSATE OF PATIENTS WITH CYSTIC FIBROSIS, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A219-A219, ISSN: 0040-6376

CONFERENCE PAPER

Saleh AD, Clarke NK, Meng C, Jacobson MR, Davies JC, Durham SR, Alton EWFW, Griesenbach Uet al., 2017, DEVELOPMENT OF ASSAYS TO ASSESS SAFETY AND EFFICACY OF LENTIVIRAL GENE THERAPY FOR CYSTIC FIBROSIS, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A57-A57, ISSN: 0040-6376

CONFERENCE PAPER

Atsumi N, Pilou A, Pringle I, Ashworth RC, Meng C, Chan M, Gill DR, Hyde S, Morgan C, Alton EWFW, Griesenbach Uet al., 2017, GENE THERAPY FOR PULMONARY ALVEOLAR PROTEINOSIS, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A72-A73, ISSN: 0040-6376

CONFERENCE PAPER

Coates M, Ito K, Alton E, Davies JCet al., 2017, RSV INFECTION LEADS TO INCREASED BINDING OF PSEUDOMONAS AERUGINOSA TO PHE508DEL CFTR EXPRESSING RESPIRATORY EPITHELIAL CELLS, Publisher: WILEY, Pages: S375-S375, ISSN: 8755-6863

CONFERENCE PAPER

Shoemark A, Frost E, Harman K, Crowley S, Ives A, Donovan J, Tan H-L, Alton EW, Bush A, Hogg C, Davies JCet al., 2017, Nasal cavity inflammation in patients with primary ciliary dyskinesia (PCD) is associated with bacterial infection, European-Respiratory-Society (ERS) International Congress, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936

CONFERENCE PAPER

Meng C, Alton E, Boyd C, Davies JC, Higgins T, Gill D, Hyde S, Griesenbach Uet al., 2017, QUANTIFICATION OF VECTOR SHEDDING AFTER LENTIVIRUS GENE TRANSFER TO MOUSE LUNG, Publisher: WILEY, Pages: S268-S269, ISSN: 8755-6863

CONFERENCE PAPER

Edmondson C, Murphy R, Moffitt K, Riberio D, Alton E, Davies JCet al., 2017, ACTIVE NEUTROPHIL ELASTASE CAN BE DETECTED IN EXHALED BREATH CONDENSATE OF PATIENTS WITH CYSTIC FIBROSIS, Publisher: WILEY, Pages: S316-S316, ISSN: 8755-6863

CONFERENCE PAPER

Meng C, Alton E, Boyd C, Davies J, Higgins T, Gill D, Hyde S, Griesenbach Uet al., 2017, Quantification of vector shedding after transduction of murine lungs with F/HN-pseudotyped lentivirus, Annual Conference of the British-Society-for-Gene-and-Cell-Therapy / Joint UK-Regenerative-Medicine-Platform Meeting, Publisher: MARY ANN LIEBERT, INC, Pages: A12-A12, ISSN: 1043-0342

CONFERENCE PAPER

Paul-Smith MC, Pytel KM, Gelinas J-F, McIntosh J, Pringle I, Davies L, Bell R, Cammack L, Moran C, Cameron L, Inoue M, Tsugumine S, Hironaka T, Gill D, Hyde SC, Nathwani A, Alton E, Griesenbach Uet al., 2017, The lung as a factory to produce secreted intrapulmonary and circulatory proteins, Annual Conference of the British-Society-for-Gene-and-Cell-Therapy / Joint UK-Regenerative-Medicine-Platform Meeting, Publisher: MARY ANN LIEBERT, INC, Pages: A11-A12, ISSN: 1043-0342

CONFERENCE PAPER

Smith WD, Bardin E, Cameron L, Edmondson CL, Farrant KV, Martin I, Murphy RA, Soren O, Turnbull AR, Wierre-Gore N, Alton EW, Bundy JG, Bush A, Connett GJ, Faust SN, Filloux A, Freemont PS, Jones AL, Takats Z, Webb JS, Williams HD, Davies JCet al., 2017, Current and future therapies for Pseudomonas aeruginosa infection in patients with cystic fibrosis, FEMS MICROBIOLOGY LETTERS, Vol: 364, ISSN: 0378-1097

JOURNAL ARTICLE

Alton EWFW, Beekman JM, Boyd AC, Brand J, Carlon MS, Connolly MM, Chan M, Conlon S, Davidson HE, Davies JC, Davies LA, Dekkers JF, Doherty A, Gea-Sorli S, Gill DR, Griesenbach U, Hasegawa M, Higgins TE, Hironaka T, Hyndman L, McLachlan G, Inoue M, Hyde SC, Innes JA, Maher TM, Moran C, Meng C, Paul-Smith MC, Pringle IA, Pytel KM, Rodriguez-Martinez A, Schmidt AC, Stevenson BJ, Sumner-Jones SG, Toshner R, Tsugumine S, Wasowicz MW, Zhu Jet al., 2017, Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis, THORAX, Vol: 72, Pages: 137-147, ISSN: 0040-6376

JOURNAL ARTICLE

Turnbull A, Lund-Palau H, Murphy R, Simbo A, Shoemark A, Wong K, Bush A, Alton E, Davies Jet al., 2016, THE T2R38 BITTER TASTE RECEPTOR AS A MODIFIER OF HOST RESPONSE TO PSEUDOMONAS AERUGINOSA IN CYSTIC FIBROSIS: DOES T2R38 GENOTYPE IMPACT ON CLINICAL INFECTION?, Publisher: BMJ PUBLISHING GROUP, Pages: A44-A44, ISSN: 0040-6376

CONFERENCE PAPER

Coates MS, Alton EWFW, Brookes DW, Ito K, Davies JCet al., 2016, INCREASED RESPIRATORY SYNCYTIAL VIRUS BURDEN LEADS TO MORE RAPID CELL DEATH IN PHE508DEL BRONCHIAL EPITHELIAL CELLS, THORAX, Vol: 71, Pages: A44-A44, ISSN: 0040-6376

JOURNAL ARTICLE

Griesenbach U, Davies JC, Alton E, 2016, Cystic fibrosis gene therapy: a mutation-independent treatment, CURRENT OPINION IN PULMONARY MEDICINE, Vol: 22, Pages: 602-609, ISSN: 1070-5287

JOURNAL ARTICLE

Turnbull AR, Lund-Palau H, Murphy R, Simbo A, Wong K, Bush A, Alton E, Davies JCet al., 2016, THE T2R38 BITTER TASTE RECEPTOR AS A MODIFIER OF HOST RESPONSE TO PSEUDOMONAS AERUGINOSA IN CYSTIC FIBROSIS: DOES T2R38 GENOTYPE IMPACT ON CLINICAL INFECTION?, PEDIATRIC PULMONOLOGY, Vol: 51, Pages: 323-323, ISSN: 8755-6863

JOURNAL ARTICLE

Alton EWFW, Boyd AC, Davies JC, Gill DR, Griesenbach U, Harrison PT, Henig N, Higgins T, Hyde SC, Innes JA, Korman MSDet al., 2016, Genetic medicines for CF: Hype versus reality, PEDIATRIC PULMONOLOGY, Vol: 51, Pages: S5-S17, ISSN: 8755-6863

JOURNAL ARTICLE

Bardin E, Bolt F, Cameron S, Alton E, Bush A, Takats Z, Davies JCet al., 2016, METABOLOMIC CHARACTERIZATION OF PSEUDOMONAS AERUGINOSA ISOLATES FROM CYSTIC FIBROSIS PATIENTS USING RAPID EVAPORATIVE IONISATION MASS SPECTROMETRY, PEDIATRIC PULMONOLOGY, Vol: 51, Pages: 312-313, ISSN: 8755-6863

JOURNAL ARTICLE

Bayfield K, Alton E, Irving S, Bush A, Horsley A, Davies Jet al., 2016, Simultaneous SF6 and N-2 gas multiple breath washout (MBW); understanding the difference between test gases, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936

CONFERENCE PAPER

Harman K, Crowley S, Waller M, Alton E, Davies Jet al., 2016, Is there a secondary defect in CFTR in the nasal epithelium of patients with primary ciliary dyskinesia?, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936

CONFERENCE PAPER

Bayfield K, Alton E, Irving S, Davies Jet al., 2016, Comparison of functional residual capacity (FRC) from two multiple breath washout (MBW) systems and body plethysmography, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936

CONFERENCE PAPER

Pytel KM, Chan M, Meng C, Martinez AR, Boyd CA, Davies JC, Gill DR, Hyde SC, Innes AJ, Alton EWFW, Griesenbach Uet al., 2016, Pre-existing immunity to human parainfluenza virus (hPIV) does not affect rSIV.F/HN-mediated transduction efficiency., Annual Conference of the British-Society-for-Gene-and-Cell-Therapy, Publisher: MARY ANN LIEBERT, INC, Pages: A19-A19, ISSN: 1043-0342

CONFERENCE PAPER

Paul-Smith MC, Bell RV, Alton WE, Alton EWFW, Griesenbach Uet al., 2016, Gene therapy for cystic fibrosis: recent progress and current aims, EXPERT OPINION ON ORPHAN DRUGS, Vol: 4, Pages: 649-658, ISSN: 2167-8707

JOURNAL ARTICLE

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