Imperial College London


Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Non-Clinical Lecturer







10.N4Commonwealth BuildingHammersmith Campus





Dr Edward Chambers is a Non-Clinical Lecturer in the Nutrition and Dietetics Research Group. His applied in vivo human research aims to advance understanding of nutritional intervention in health and disease.

His main area of interest is investigating the interplay between dietary fibre and the composition and functional activities of the gut microbiome in the regulation of metabolic homeostasis in humans. At Imperial College London, his principal responsibility has been the conduct and management of BBSRC and NIHR BRC funded projects which have investigated the beneficial role of the gut-derived short chain fatty acid (SCFA) propionate to metabolic health. Published studies have developed in vivo proof-of-concept for propionate as a novel therapeutic to improve body weight management and reduce hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD).



Frampton J, Murphy K, Frost G, et al., 2021, Higher dietary fibre intake is associated with increased skeletal muscle mass and strength in adults aged 40 years and older, Journal of Cachexia, Sarcopenia and Muscle, Vol:12, ISSN:2190-6009, Pages:2134-2144

Frampton J, Edinburgh R, Ogden H, et al., 2021, The acute effect of fasted exercise on energy intake, energy expenditure, subjective hunger and gastrointestinal hormone release compared to fed exercise in healthy individuals: A systematic review and network meta-analysis, International Journal of Obesity, Vol:46, ISSN:0307-0565, Pages:255-268

Wu Y, Posma JM, Holmes E, et al., 2021, Odd chain fatty acids are not robust biomarkers for dietary intake of fiber, Molecular Nutrition and Food Research, Vol:65, ISSN:1613-4125, Pages:1-8

Prokopidis K, Chambers E, Ni Lochlainn M, et al., 2021, Mechanisms Linking the Gut-Muscle Axis With Muscle Protein Metabolism and Anabolic Resistance: Implications for Older Adults at Risk of Sarcopenia, Frontiers in Physiology, Vol:12

Frampton J, Cobbold B, Nozdrin M, et al., 2021, The effect of a single bout of continuous aerobic exercise on glucose, insulin and glucagon concentrations compared to resting conditions in healthy adults: a systematic review, meta-analysis and meta-regression, Sports Medicine, Vol:51, ISSN:0112-1642, Pages:1949-1966

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