Summary
Dr Edward Chambers is a Non-Clinical Lecturer in the Nutrition and Dietetics Research Group. His applied in vivo human research aims to advance understanding of nutritional intervention in health and disease.
His main area of interest is investigating the interplay between dietary fibre and the composition and functional activities of the gut microbiome in the regulation of metabolic homeostasis in humans. At Imperial College London, his principal responsibility has been the conduct and management of BBSRC and NIHR BRC funded projects which have investigated the beneficial role of the gut-derived short chain fatty acid (SCFA) propionate to metabolic health. Published studies have developed in vivo proof-of-concept for propionate as a novel therapeutic to improve body weight management and reduce hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD).
Publications
Journals
Frampton J, Murphy K, Frost G, et al., 2021, Higher dietary fibre intake is associated with increased skeletal muscle mass and strength in adults aged 40 years and older, Journal of Cachexia, Sarcopenia and Muscle, ISSN:2190-6009
Frampton J, Cobbold B, Nozdrin M, et al., 2021, The effect of a single bout of continuous aerobic exercise on glucose, insulin and glucagon concentrations compared to resting conditions in healthy adults: a systematic review, meta-analysis and meta-regression, Sports Medicine, Vol:51, ISSN:0112-1642, Pages:1949-1966
Wu Y, Posma JM, Holmes E, et al., 2021, Odd chain fatty acids are not robust biomarkers for dietary intake of fiber, Molecular Nutrition and Food Research, ISSN:1613-4125
Wallis GA, Chambers ES, 2021, UK Nutrition Research Partnership (NRP) workshop: Improving our understanding of the metabolic interplay between nutrition and physical activity (IN-PACT), Nutrition Bulletin, ISSN:1471-9827
Brignardello J, Fountana S, Posma JM, et al., 2021, Characterization of diet-dependent temporal changes in circulating short-chain fatty acid concentrations: A randomized crossover dietary trial, The American Journal of Clinical Nutrition, ISSN:0002-9165