Summary
Dr Edward Chambers is a Non-Clinical Lecturer in the Nutrition and Dietetics Research Group. His applied in vivo human research aims to advance understanding of nutritional intervention in health and disease.
His main area of interest is investigating the interplay between dietary fibre and the composition and functional activities of the gut microbiome in the regulation of metabolic homeostasis in humans. At Imperial College London, his principal responsibility has been the conduct and management of BBSRC and NIHR BRC funded projects which have investigated the beneficial role of the gut-derived short chain fatty acid (SCFA) propionate to metabolic health. Published studies have developed in vivo proof-of-concept for propionate as a novel therapeutic to improve body weight management and reduce hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD).
Publications
Journals
Frampton J, Serrano Contreras J, Garcia Perez I, et al., 2023, The metabolic interplay between dietary carbohydrate and exercise and its role in acute appetite-regulation in males: a randomised controlled study, The Journal of Physiology, Vol:601, ISSN:0022-3751, Pages:3461-3480
Cherta-Murillo A, Danckert NP, Valdivia-Garcia M, et al., 2023, Gut microbiota fermentation profiles of pre-digested mycoprotein (Quorn) using faecal batch cultures <i>in vitro</i>: a preliminary study, International Journal of Food Sciences and Nutrition, Vol:74, ISSN:0963-7486, Pages:327-337
Garcia-Perez I, Posma JM, Chambers ES, et al., 2023, Dietary metabotype modelling predicts individual responses to dietary interventions (Vol 1, pg 355, 2020) (Retraction of Vol 1, Pg 355, 2020), Nature Food, Vol:4, Pages:269-269
Lu H, George J, Eslam M, et al., 2023, Discriminatory changes in circulating metabolites as a predictor of hepatocellular cancer in patients with MAFLD, Liver Cancer, Vol:12, ISSN:2235-1795, Pages:19-31
Chew W, Lim YP, Lim WS, et al., 2023, Gut-muscle crosstalk. A perspective on influence of microbes on muscle function, Frontiers in Medicine, Vol:9