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Hennah L, Seckl M, Ghorani E, 2023, Novel approaches to managing gestational trophoblastic tumors in the age of immunotherapy., Int J Gynecol Cancer, Vol: 33, Pages: 414-419
The discovery that anti-programmed death-1 antibody (anti-PD-1) immunotherapy can cure patients with multidrug-resistant gestational trophoblastic neoplasia provides a new powerful and low toxicity treatment. This heralds an era within which the majority of patients, including those with previously difficult to treat disease, can expect to achieve long-term remission. This development should prompt a rethink of how patients with this rare disease are managed, focusing on maximizing cure rate with minimal exposure to toxic chemotherapy.
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