DrEdwardKnock

Faculty of Medicine, School of Public Health

Research Associate in Mathematical Modelling

Contact

Location

Norfolk PlaceSt Mary's Campus

Summary

My main interest is the statistical analysis of stochastic compartmental models for epidemics under a Bayesian framework.

Since March 2020 I have been working on the real-time modelling of the COVID-19 pandemic in the UK as part of the Imperial COVID-19 Response Team with Dr Marc Baguelin, Dr Anne Cori and Prof Neil Ferguson.

As part of this work we have been developing analyical and computational tools for use in potential future pandemics as part of the NIHR Health Protection Research Unit in Modelling and Health Economics.

Previous work includes studying contact tracing, household models, and other infectious diseases such as influenza and human African trypanosomiasis.

Publications

Journals

Sonabend R, Whittles LK, Imai N, et al.Sonabend R, Whittles LK, Imai N, Perez Guzman PN, Knock E, Rawson T, Gaythorpe KA, Djaafara A, Hinsley W, Fitzjohn R, Lees JA, Thekke Kanapram D, Volz E, Ghani A, Ferguson NM, Baguelin M, Cori A close, 2021, Non-pharmaceutical interventions, vaccination, and the SARS-CoV-2 delta variant in England: a mathematical modelling study, The Lancet, Vol:398, ISSN:0140-6736, Pages:1825-1835

Knock ES, Whittles LK, Lees JA, et al.Knock ES, Whittles LK, Lees JA, Perez-Guzman PN, Verity R, FitzJohn RG, Gaythorpe KAM, Imai N, Hinsley W, Okell LC, Rosello A, Kantas N, Walters CE, Bhatia S, Watson OJ, Whittaker C, Cattarino L, Boonyasiri A, Djaafara BA, Fraser K, Fu H, Wang H, Xi X, Donnelly CA, Jauneikaite E, Laydon DJ, White PJ, Ghani AC, Ferguson NM, Cori A, Baguelin M, Knock E, Whittles L, Lees J, Perez-Guzman P, Verity R, FitzJohn R, Gaythorpe KAM, Imai N, Hinsley W, Okell L, Rosello A, Kantas N, Walters C, Bhatia S, Watson O, Whittaker C, Cattarino L, Boonyasiri A, Djaafara B, Fraser K, Fu H, Wang H, Xi X, Donnelly C, Jauneikaite E, Laydon D, White P, Ghani A, Ferguson N, Cori A, Baguelin M close, 2021, Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England, Science Translational Medicine, Vol:13, ISSN:1946-6234, Pages:1-12

FitzJohn RG, Knock ES, Whittles LK, et al.FitzJohn RG, Knock ES, Whittles LK, Perez-Guzman PN, Bhatia S, Guntoro F, Watson OJ, Whittaker C, Ferguson NM, Cori A, Baguelin M, Lees JA close, 2021, Reproducible parallel inference and simulation of stochastic state space models using odin, dust, and mcstate [version 2; peer review: 2 approved], Wellcome Open Research, Vol:5, ISSN:2398-502X

Hogan AB, Winskill P, Watson OJ, et al.Hogan AB, Winskill P, Watson OJ, Walker PGT, Whittaker C, Baguelin M, Brazeau NF, Charles GD, Gaythorpe KAM, Hamlet A, Knock E, Laydon DJ, Lees JA, Løchen A, Verity R, Whittles LK, Muhib F, Hauck K, Ferguson NM, Ghani AC close, 2021, Within-country age-based prioritisation, global allocation, and public health impact of a vaccine against SARS-CoV-2: a mathematical modelling analysis, Vaccine, Vol:39, ISSN:0264-410X, Pages:2995-3006

Crump RE, Huang C, Knock ES, et al.Crump RE, Huang C, Knock ES, Spencer SEF, Brown PE, Miaka EM, Shampa C, Keeling MJ, Rock KS close, 2021, Quantifying epidemiological drivers of gambiense human African Trypanosomiasis across the Democratic Republic of Congo, Plos Computational Biology, Vol:17, ISSN:1553-734X

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