Imperial College London


Faculty of EngineeringDepartment of Chemical Engineering

Visiting Professor



+44 (0)20 7594 6620e.pistikopoulos




C508Roderic Hill BuildingSouth Kensington Campus





Research Interests

The objective of my research programme is to develop fundamental theory and optimization based methodologies and computational tools that enable process engineers to analyse, design and evaluate process manufacturing systems which are economically attractive, energy efficient and environmentally benign, while at the same time exhibit good performance characteristics like flexibility, controllability, robustness, reliability and safety. Our research involves three main strands:

Process Synthesis and the Environment Here we are concerned with the development of process integration and pollution prevention strategies for the design and operation of plant-wide sustainable processes. Novel process synthesis modelling concepts are explored together with life-cycle and environmental impact assessment aspects, leading to new designs which feature step-change improvements in energy efficiency, waste minimization and process sustainability.

Integration of operability objectives in process design and operation Our work here has centred on the development and implementation of novel analytical tools to simultaneously assess process flexibility, controllability, robustness, reliability and availability of complex process manufacturing systems and the systematic incorporation of these tools at the design and operational level.

Process Optimization under uncertainty - Theory, algorithms and applications Here we develop the fundamental underlying mathematical theory, numerical algorithms and efficient computational tools for the solution of multi-parametric and stochastic mixed integer optimization problems, which arise in the context of the work described in the other two research strands.


Selected Research Projects

  1. "Modular Synthesis Framework for Process Synthesis" in collaboration with Petros Proios download PDF 
  2. "Process Design Toolbox for Energy Efficiency" in collaboration with Dr. Nikos Bozinis and Dr. Vivek Dua download PDF
  3. "Integration of Process Design and Control" in collaboration with Prof. John Perkins and Vasilis Sakizlis download PDF
  4. "A revolutionary approach for on-line control and optimization via off-line optimization" in collaboration with J. Perkins, N. Bozinis, V. Dua and V. Sakizlis download PDF