Imperial College London
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Dr Ellie Sherrard-Smith

Faculty of Medicine, School of Public Health

Advanced Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 3229e.sherrard-smith

 
 
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Location

 

G27Praed StreetSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sherrard-Smith:2018:10.1038/s41467-018-07357-w,
author = {Sherrard-Smith, E and Griffin, J and Winskill, P and Corbel, V and Pennetier, C and Djénontin, A and Moore, S and Richardson, J and Müller, P and Edi, C and Protopopoff, N and Oxborough, R and Agossa, F and N'Guessan, R and Rowland, M and Churcher, T},
doi = {10.1038/s41467-018-07357-w},
journal = {Nature Communications},
title = {Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa},
url = {http://dx.doi.org/10.1038/s41467-018-07357-w},
volume = {9},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Indoor residual spraying (IRS) is an important part of malaria control. There is a growing list of insecticide classes; pyrethroids remain the principal insecticide used in bednets but recently, novel non-pyrethroid IRS products, with contrasting impacts, have been introduced. There is an urgent need to better assess product efficacy to help decision makers choose effective and relevant tools for mosquito control. Here we use experimental hut trial data to characterise the entomological efficacy of widely-used, novel IRS insecticides. We quantify their impact against pyrethroid-resistant mosquitoes and use a Plasmodium falciparum transmission model to predict the public health impact of different IRS insecticides. We report that long-lasting IRS formulations substantially reduce malaria, though their benefit over cheaper, shorter-lived formulations depends on local factors including bednet use, seasonality, endemicity and pyrethroid resistance status of local mosquito populations. We provide a framework to help decision makers evaluate IRS product effectiveness.
AU  - Sherrard-Smith,E
AU  - Griffin,J
AU  - Winskill,P
AU  - Corbel,V
AU  - Pennetier,C
AU  - Djénontin,A
AU  - Moore,S
AU  - Richardson,J
AU  - Müller,P
AU  - Edi,C
AU  - Protopopoff,N
AU  - Oxborough,R
AU  - Agossa,F
AU  - N'Guessan,R
AU  - Rowland,M
AU  - Churcher,T
DO  - 10.1038/s41467-018-07357-w
PY  - 2018///
SN  - 2041-1723
TI  - Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa
T2  - Nature Communications
UR  - http://dx.doi.org/10.1038/s41467-018-07357-w
UR  - http://hdl.handle.net/10044/1/65787
VL  - 9
ER  -
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