Imperial College London
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Dr Ellie Sherrard-Smith

Faculty of Medicine, School of Public Health

Advanced Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 3229e.sherrard-smith

 
 
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Location

 

G27Praed StreetSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Montoya:2022:10.1101/2022.07.01.498466,
author = {Montoya, LF and Martí-Soler, H and Máquina, M and Comiche, K and Cuamba, I and Alafo, C and Koekemoer, LL and Sherrard-Smith, E and Bassat, Q and Galatas, B and Aide, P and Cuamba, N and Jotamo, D and Saúte, F and Paaijmans, KP},
doi = {10.1101/2022.07.01.498466},
title = {The mosquito vectors that sustained malaria transmission during the Magude project despite the combined deployment of indoor residual spraying, insecticide-treated nets and mass-drug administration},
url = {http://dx.doi.org/10.1101/2022.07.01.498466},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:title>Abstract</jats:title><jats:p>The “Magude project” aimed but failed to interrupt local malaria transmission in Magude district, southern Mozambique, by using a comprehensive package of interventions, including indoor residual spraying (IRS), pyrethroid-only long-lasting insecticide treated nets (LLINs) and mass-drug administration (MDA). Here we present detailed information on the vector species that sustained malaria transmission, their association with malaria incidence and behaviors, and their amenability to the implemented control interventions. Mosquitoes were collected monthly between May 2015 and October 2017 in six sentinel sites in Magude district, using CDC light traps both indoors and outdoors. <jats:italic>Anopheles arabiensis</jats:italic> was the main vector during the project, while <jats:italic>An. funestus s.s</jats:italic>., <jats:italic>An. merus, An. parensis</jats:italic> and <jats:italic>An. squamosus</jats:italic> likely played a secondary role. The latter two species have never previously been found positive for <jats:italic>Plasmodium falciparum</jats:italic> in southern Mozambique. The intervention package successfully reduced vector sporozoite rates in all species throughout the project. IRS was effective in controlling <jats:italic>An. funestus s.s</jats:italic>. and <jats:italic>An. parensis</jats:italic>, which virtually disappeared after its first implementation, but less effective at controlling <jats:italic>An. arabiensis</jats:italic>. Despite suboptimal use, LLINs likely provided significant protection against <jats:italic>An. arabiensis</jats:italic> and <jats:italic>An. merus</jats:italic> that sought their host largely indoors when people where in bed. Adding IRS on top of LLINs and MDA likely added value to the control of malaria vectors during the Magude project. Futur
AU  - Montoya,LF
AU  - Martí-Soler,H
AU  - Máquina,M
AU  - Comiche,K
AU  - Cuamba,I
AU  - Alafo,C
AU  - Koekemoer,LL
AU  - Sherrard-Smith,E
AU  - Bassat,Q
AU  - Galatas,B
AU  - Aide,P
AU  - Cuamba,N
AU  - Jotamo,D
AU  - Saúte,F
AU  - Paaijmans,KP
DO  - 10.1101/2022.07.01.498466
PY  - 2022///
TI  - The mosquito vectors that sustained malaria transmission during the Magude project despite the combined deployment of indoor residual spraying, insecticide-treated nets and mass-drug administration
UR  - http://dx.doi.org/10.1101/2022.07.01.498466
ER  -
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