Imperial College London

Dr Evangelos Triantafyllou

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Advanced Research Fellow
 
 
 
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Contact

 

e.triantafyllou Website

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Summary

Dr Evangelos Triantafyllou is an Advanced Research Fellow (Liver Immunology Group) based in the Division of Digestive Disease, part of the Department of Metabolism, Digestion and Reproduction (St Mary's & Hammersmith campuses)

Evangelos completed his PhD in Immunology in 2017 at King’s College London where he studied the mechanisms of immune-mediated injury in acute liver failure, under the supervision of Dr Harry Antoniades. He spent one year of his doctoral work on secondment to the University of Birmingham in collaboration with Dr Chris Weston and Prof David Adams. Evangelos took up his first postdoctoral position at Imperial College funded by the Rosetrees Trust (2017-19), and then was awarded a prestigious Imperial College Research Fellowship (2018-22) sponsored by Prof Mark Thursz, which supported him to define his research niche investigating the interactions of immune cells in the liver.

Evangelos’ research focuses on innate immune responses in acute and chronic liver injury. He studies the cellular and molecular mechanisms by which, for example, blood monocytes and liver macrophages contribute to the pathophysiology of acute liver failure, cirrhosis and acute-on-chronic liver failure. He is interested in the role of checkpoint pathways in mediating immune regulation in the liver and their therapeutic targeting for developing new treatments for patients with liver disease.

employment


2020-present: Advanced Research Fellow (Imperial College)

2018-2020: Imperial College Research Fellow (Imperial College)

2017-2018: Research Associate (Imperial College)

2013-2017: Research Assistant (King's College London)

2012-2013: Research Assistant (King's College Hospital)

education

2013-2017: PhD Immunology (King's College London)

2011-2012: MSc Developmental Biology (University of Bath)

2006-2011: BSc Biology (University of Athens)

Selected Publications

Journal Articles

Gudd CLC, Au L, Triantafyllou E, et al., 2021, Activation and transcriptional profile of monocytes and CD8+ T cells are altered in checkpoint inhibitor-related hepatitis, Journal of Hepatology, Vol:75, ISSN:0168-8278, Pages:177-189

Singanayagam A, Triantafyllou E, 2021, Macrophages in Chronic Liver Failure: Diversity, Plasticity and Therapeutic Targeting, Frontiers in Immunology, Vol:12

Triantafyllou E, Gudd CLC, Mawhin M-A, et al., 2021, PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury, Journal of Clinical Investigation, Vol:131, ISSN:0021-9738

Triantafyllou E, Woollard K, McPhail M, et al., 2018, The role of monocytes and macrophages in acute and acute-on-chronic liver failure, Frontiers in Immunology, Vol:9, ISSN:1664-3224

Bernsmeier C, Triantafyllou E, Brenig R, et al., 2018, CD14+ CD15− HLA-DR− myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure, Gut, Vol:67, ISSN:0017-5749, Pages:1155-1167

Triantafyllou E, Pop O, Possamai L, et al., 2017, MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure, Gut, Vol:67, ISSN:1468-3288, Pages:333-347

More Publications