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@article{Cordova:2021:10.1016/j.clnu.2021.08.009,
author = {Cordova, R and Kliemann, N and Huybrechts, I and Rauber, F and Vamos, EP and Levy, RB and Wagner, K-H and Viallon, V and Casagrande, C and Nicolas, G and Dahm, CC and Zhang, J and Halkjær, J and Tjønneland, A and Boutron-Ruault, M-C and Mancini, FR and Laouali, N and Katzke, V and Srour, B and Jannasch, F and Schulze, MB and Masala, G and Grioni, S and Panico, S and van, der Schouw YT and Derksen, JWG and Rylander, C and Skeie, G and Jakszyn, P and Rodriguez-Barranco, M and Huerta, JM and Barricarte, A and Brunkwall, L and Ramne, S and Bodén, S and Perez-Cornago, A and Heath, AK and Vineis, P and Weiderpass, E and Monteiro, CA and Gunter, MJ and Millett, C and Freisling, H},
doi = {10.1016/j.clnu.2021.08.009},
journal = {Clinical Nutrition},
pages = {5079--5088},
title = {Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study},
url = {http://dx.doi.org/10.1016/j.clnu.2021.08.009},
volume = {40},
year = {2021}
}

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TY  - JOUR
AB  - BackgroundThere is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity.MethodsThis prospective cohort included 348 748 men and women aged 25–70 years. Participants were recruited between 1992 and 2000 from 9 European countries in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Two body weight measures were available, at baseline and after a median follow-up time of 5 years. Foods and drinks were assessed at baseline by dietary questionnaires and classified according to their degree of processing using NOVA classification. Multilevel mixed linear regression was used to estimate the association between UPF consumption and body weight change (kg/5 years). To estimate the relative risk of becoming overweight or obese after 5 years we used Poisson regression stratified according to baseline body mass index (BMI).ResultsAfter multivariable adjustment, higher UPF consumption (per 1 SD increment) was positively associated with weight gain (0·12 kg/5 years, 95% CI 0·09 to 0·15). Comparing highest vs. lowest quintile of UPF consumption was associated with a 15% greater risk (95% CI 1·11, 1·19) of becoming overweight or obese in normal weight participants, and with a 16% greater risk (95% CI 1·09, 1·23) of becoming obese in participants who were overweight at baseline.ConclusionsThese results are supportive of public health campaigns to substitute UPF for less processed alternatives for obesity prevention and weight management.
AU  - Cordova,R
AU  - Kliemann,N
AU  - Huybrechts,I
AU  - Rauber,F
AU  - Vamos,EP
AU  - Levy,RB
AU  - Wagner,K-H
AU  - Viallon,V
AU  - Casagrande,C
AU  - Nicolas,G
AU  - Dahm,CC
AU  - Zhang,J
AU  - Halkjær,J
AU  - Tjønneland,A
AU  - Boutron-Ruault,M-C
AU  - Mancini,FR
AU  - Laouali,N
AU  - Katzke,V
AU  - Srour,B
AU  - Jannasch,F
AU  - Schulze,MB
AU  - Masala,G
AU  - Grioni,S
AU  - Panico,S
AU  - van,der Schouw YT
AU  - Derksen,JWG
AU  - Rylander,C
AU  - Skeie,G
AU  - Jakszyn,P
AU  - Rodriguez-Barranco,M
AU  - Huerta,JM
AU  - Barricarte,A
AU  - Brunkwall,L
AU  - Ramne,S
AU  - Bodén,S
AU  - Perez-Cornago,A
AU  - Heath,AK
AU  - Vineis,P
AU  - Weiderpass,E
AU  - Monteiro,CA
AU  - Gunter,MJ
AU  - Millett,C
AU  - Freisling,H
DO  - 10.1016/j.clnu.2021.08.009
EP  - 5088
PY  - 2021///
SN  - 0261-5614
SP  - 5079
TI  - Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study
T2  - Clinical Nutrition
UR  - http://dx.doi.org/10.1016/j.clnu.2021.08.009
UR  - https://www.sciencedirect.com/science/article/pii/S0261561421003897?via%3Dihub
UR  - http://hdl.handle.net/10044/1/91443
VL  - 40
ER  -

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