Imperial College London
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DrEdwardMullins

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Senior Lecturer in Obstetrics (Public, Global and D
 
 
 
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Contact

 

edward.mullins Website CV

 
 
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Location

 

St Mary's HospitalClarence WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mullins:2021:10.1101/2021.01.06.21249325,
author = {Mullins, E and Hudak, M and Banerjee, J and Getzlaff, T and Townson, J and Barnette, K and Playle, R and Bourne, T and Lees, C},
doi = {10.1101/2021.01.06.21249325},
journal = {Ultrasound in Obstetrics and Gynecology},
title = {Pregnancy and neonatal outcomes of COVID-19 – co-reporting of common outcomes from the PAN-COVID and AAP SONPM registry},
url = {http://dx.doi.org/10.1101/2021.01.06.21249325},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <h4>Background</h4> Few large, cohort studies report data on individual’s maternal, fetal, perinatal, and neonatal outcomes associated with SARS-CoV-2 infection in pregnancy. We report outcomes from a collaboration formed early during the pandemic between the investigators of two registries, the UK and global Pregnancy and Neonatal outcomes in COVID-19 (PAN-COVID) study and the US American Academy of Pediatrics Section on Neonatal Perinatal Medicine (AAP SONPM) National Perinatal COVID-19 Registry. <h4>Methods</h4> PAN-COVID (suspected or confirmed SARS-CoV-2 infection at any stage in pregnancy) and the AAP SONPM registry (positive maternal testing for SARS-CoV-2 from 14 days before delivery to 3 days after delivery) studies collected data on maternal, fetal, perinatal and neonatal outcomes. PAN-COVID results are presented as all inclusions and those with confirmed SARS-CoV-2 infection only. <h4>Results</h4> We report 4004 women in pregnancy affected by suspected or confirmed SARS-CoV-2 infection (1606 from PAN-COVID and 2398 from the AAP SONPM) from January 1 st 2020 to July 25 th 2020 (PAN-COVID) and August 8 th (AAP SONPM). For obstetric outcomes in PAN-COVID and AAP SONPM, respectively, maternal death occurred in 0.5% and 0.17%, early neonatal death in 0.2% and 0.3%, and stillbirth in 0.50% and 0.65% of women. Delivery was pre-term (<37 weeks gestation) in 12% of all women in PAN-COVID, in 16.2% of those women with confirmed infection in PAN-COVID and 16.2% of women in AAP SONPM. Very preterm delivery (< 27 weeks’ gestation) occurred in 0.6% in PAN-COVID and 0.7% in AAP SONPM. Neonatal SARS-CoV-2 infection was reported in 0.8% of PAN-COVID all inclusions, 2.0% in PAN-COVID confirmed infections and 1.8% in the AAP SONPM study; the proportions of babies tested were 9.5%, 20.7% and 87.2% respectively. The proportion of SGA babies was 8.2% in PAN-COVID all inclusions, 9.7% in PAN-COVID confirmed infection and 9.6
AU  - Mullins,E
AU  - Hudak,M
AU  - Banerjee,J
AU  - Getzlaff,T
AU  - Townson,J
AU  - Barnette,K
AU  - Playle,R
AU  - Bourne,T
AU  - Lees,C
DO  - 10.1101/2021.01.06.21249325
PY  - 2021///
SN  - 0960-7692
TI  - Pregnancy and neonatal outcomes of COVID-19 – co-reporting of common outcomes from the PAN-COVID and AAP SONPM registry
T2  - Ultrasound in Obstetrics and Gynecology
UR  - http://dx.doi.org/10.1101/2021.01.06.21249325
ER  -
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