Imperial College London
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DrEdwardMullins

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Senior Lecturer in Obstetrics (Public, Global and D
 
 
 
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Contact

 

edward.mullins Website CV

 
 
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Location

 

St Mary's HospitalClarence WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mullins:2021:10.1002/uog.23619,
author = {Mullins, E and Hudak, ML and Banerjee, J and Getzlaff, T and Townson, J and Barnette, K and Playle, R and Bourne, T and Lees, C and PAN-COVID, investigators and the National Perinatal COVID-19 Registry Study Group},
doi = {10.1002/uog.23619},
journal = {Ultrasound in Obstetrics and Gynecology},
pages = {5733--581},
title = {Pregnancy and neonatal outcomes of COVID-19: co-reporting of common outcomes from PAN-COVID and AAP SONPM registries},
url = {http://dx.doi.org/10.1002/uog.23619},
volume = {57},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVE: Few large cohort studies have reported data on maternal, fetal, perinatal and neonatal outcomes associated with SARS-CoV-2 infection in pregnancy. We report the outcome of infected pregnancies from a collaboration formed early during the pandemic between the investigators of two registries, the UK and global Pregnancy and Neonatal outcomes in COVID-19 (PAN-COVID) study and the US American Academy of Pediatrics Section on Neonatal Perinatal Medicine (AAP SONPM) National Perinatal COVID-19 Registry. METHODS: This was an analysis of data from the PAN-COVID registry (January 1st to July 25th 2020), which includes pregnancies with suspected or confirmed maternal SARS-CoV-2 infection at any stage in pregnancy, and the AAP SONPM National Perinatal COVID-19 registry (April 4th to August 8th 2020), which includes pregnancies with positive maternal testing for SARS-CoV-2 from 14 days before delivery to 3 days after delivery. The registries collected data on maternal, fetal, perinatal and neonatal outcomes. The PAN-COVID results are presented both overall for pregnancies with suspected or confirmed SARS-CoV-2 infection and separately in those with confirmed infection. RESULTS: We report on 4005 pregnant women with suspected or confirmed SARS-CoV-2 infection (1606 from PAN-COVID and 2399 from AAP SONPM). For obstetric outcomes, in PAN-COVID overall, those with confirmed infection in PAN-COVID and AAP SONPM, respectively, maternal death occurred in 0.5%, 0.5% and 0.2% of cases, early neonatal death in 0.2%, 0.3% and 0.3% of cases and stillbirth in 0.5%, 0.6% and 0.4% of cases. Delivery was pre-term (<37 weeks' gestation) in 12.0% of all women in PAN-COVID, in 16.2% of those women with confirmed infection in PAN-COVID and in 15.7% of women in AAP SONPM. Extremely preterm delivery (< 27 weeks' gestation) occurred in 0.5% of cases in PAN-COVID and 0.3% in AAP SONPM. Neonatal SARS-CoV-2 infection was reported in 0.8% of all deliver
AU  - Mullins,E
AU  - Hudak,ML
AU  - Banerjee,J
AU  - Getzlaff,T
AU  - Townson,J
AU  - Barnette,K
AU  - Playle,R
AU  - Bourne,T
AU  - Lees,C
AU  - PAN-COVID,investigators and the National Perinatal COVID-19 Registry Study Group
DO  - 10.1002/uog.23619
EP  - 581
PY  - 2021///
SN  - 0960-7692
SP  - 5733
TI  - Pregnancy and neonatal outcomes of COVID-19: co-reporting of common outcomes from PAN-COVID and AAP SONPM registries
T2  - Ultrasound in Obstetrics and Gynecology
UR  - http://dx.doi.org/10.1002/uog.23619
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33620113
UR  - https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.23619
UR  - http://hdl.handle.net/10044/1/86522
VL  - 57
ER  -
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