Imperial College London
Portrait Picture

ProfessorLizSimpson

Faculty of Medicine, Department of Immunology and Inflammation

Senior Research Investigator
 
 
 
//

Contact

 

elizabeth.simpson

 
 
//

Location

 

Commonwealth BuildingHammersmith Campus

//

Summary

 

Publications

Publication Type
Year
to

224 results found

Vendetti S, Chai JG, Dyson J, Simpson E, Lombardi G, Lechler Ret al., 2000, Anergic T cells inhibit the antigen-presenting function of dendritic cells, JOURNAL OF IMMUNOLOGY, Vol: 165, Pages: 1175-1181, ISSN: 0022-1767

Journal article

Rivas C, Chandler P, Melo JV, Simpson E, Apperley JFet al., 2000, Absence of <i>in vitro</i> or <i>in vivo</i> bystander effects in a thymidine kinase-transduced murine T lymphoma, CANCER GENE THERAPY, Vol: 7, Pages: 954-962, ISSN: 0929-1903

Journal article

Scott D, Addey C, Ellis P, James E, Mitchell MJ, Saut N, Jurcevic S, Simpson Eet al., 2000, Dendritic cells permit identification of genes encoding MHC class II-restricted epitopes of transplantation antigens, IMMUNITY, Vol: 12, Pages: 711-720, ISSN: 1074-7613

Journal article

Warren EH, Gavin MA, Simpson E, Chandler P, Page DC, Disteche C, Stankey KA, Greenberg PD, Riddell SRet al., 2000, The human UTY gene encodes a novel HLA-BS-restricted H-Y antigen, JOURNAL OF IMMUNOLOGY, Vol: 164, Pages: 2807-2814, ISSN: 0022-1767

Journal article

Haywood MEK, Hogarth MB, Slingsby JH, Rose SJ, Allen PJ, Thompson EM, Maibaum MA, Chandler P, Davies KA, Simpson E, Walport MJ, Morley BJet al., 2000, Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice, ARTHRITIS AND RHEUMATISM, Vol: 43, Pages: 349-355, ISSN: 0004-3591

Journal article

Miller ARM, Rivas C, Chandler P, Simpson E, Melo JV, Apperley JFet al., 1999, Development of an immune response to the truncated low affinity nerve growth factor receptor in mice., BLOOD, Vol: 94, Pages: 414B-414B, ISSN: 0006-4971

Journal article

Jhaver KG, Chandler P, Simpson E, Mellor ALet al., 1999, Thymocyte antigens do not induce tolerance in the CD4+T cell compartment, JOURNAL OF IMMUNOLOGY, Vol: 163, Pages: 4851-4858, ISSN: 0022-1767

Journal article

Basarab T, Picard JK, Simpson E, Russell-Jones Ret al., 1999, Melanoma antigen-encoding gene expression in melanocytic naevi and cutaneous malignant melanomas, BRITISH JOURNAL OF DERMATOLOGY, Vol: 140, Pages: 106-108, ISSN: 0007-0963

Journal article

Ehrmann IE, Ellis PS, Mazeyrat S, Duthie S, Brockdorff N, Mattei MG, Gavin MA, Affara NA, Brown GM, Simpson E, Mitchell MJ, Scott DMet al., 1998, Characterization of genes encoding translation initiation factor eIF-2γ in mouse and human:: sex chromosome localization, escape from X-inactivation and evolution, HUMAN MOLECULAR GENETICS, Vol: 7, Pages: 1725-1737, ISSN: 0964-6906

Journal article

Hogarth MB, Slingsby JH, Allen PJ, Thompson EM, Chandler P, Davies KA, Simpson E, Morley BJ, Walport MJet al., 1998, Multiple lupus susceptibility loci map to chromosome 1 in BXSB mice, JOURNAL OF IMMUNOLOGY, Vol: 161, Pages: 2753-2761, ISSN: 0022-1767

Journal article

Simpson E, 1998, Minor transplantation antigens - Animal models for human host-versus-graft, graft-versus-host, and graft-versus-leukemia reactions, TRANSPLANTATION, Vol: 65, Pages: 611-616, ISSN: 0041-1337

Journal article

Simpson E, 1998, Much ado about minor histocompatibility antigens, Immunology Today, Vol: 19, Pages: 108-112, ISSN: 0167-5699

Journal article

Simpson E, Roopenian D, Goulmy E, 1998, Much ado about minor histocompatibility antigens, IMMUNOLOGY TODAY, Vol: 19, Pages: 108-112, ISSN: 0167-5699

Journal article

Simpson E, 1998, Minor transplantation antigens: mouse models for human host-versus-graft, graft-versus-host and graft-versus-leukemia reactions., Arch Immunol Ther Exp (Warsz), Vol: 46, Pages: 331-339, ISSN: 0004-069X

Minor transplantation or histocompatibility (H) antigens are barriers to the transplantation of organs and tissues between genetically non-identical individuals who are matched for transplantation antigens encoded by the major histocompatibility complex (MHC), H2 in mice and HLA in humans. Recognition of minor H antigens by T cells can lead to host-versus-graft (HvG) rejection of organs and, in bone marrow transplantation, to life threatening graft-versus-host (GvH) reactions, although if these can be controlled, clinically useful graft-versus-leukemia (GvL) reactions can be obtained. This review describes the early in vivo studies that laid the foundations of our understanding that minor H antigens are the product of genetic polymorphisms, the subsequent in vitro work which has identified these at the molecular level as peptides presented to T cells by self MHC molecules, and the most recent developments, which have seen the use of minor H specific T cells clones and sophisticated biochemical and molecular biological approaches to identify genes encoding them.

Journal article

Simpson E, Roopenian D, 1997, Minor histocompatibility antigens, CURRENT OPINION IN IMMUNOLOGY, Vol: 9, Pages: 655-661, ISSN: 0952-7915

Journal article

Scott DM, Ehrmann JE, Ellis PS, Chandler PR, Simpson Eet al., 1997, Why do some females reject males? The molecular basis for male-specific graft rejection, JOURNAL OF MOLECULAR MEDICINE-JMM, Vol: 75, Pages: 103-114, ISSN: 0946-2716

Journal article

Simpson E, Scott D, Chandler P, 1997, The male-specific histocompatibility antigen, H-Y: A history of transplantation, immune response genes, sex determination and expression cloning, ANNUAL REVIEW OF IMMUNOLOGY, Vol: 15, Pages: 39-61, ISSN: 0732-0582

Journal article

Greenfield A, Scott D, Pennisi D, Ehrmann I, Ellis P, Cooper L, Simpson E, Koopman Pet al., 1996, An H-YDb epitope is encoded by a novel mouse Y chromosome gene, NATURE GENETICS, Vol: 14, Pages: 474-478, ISSN: 1061-4036

Journal article

Slingsby JH, Dyson PJ, Morley BJ, Walport MJ, Simpson Eet al., 1996, Localization of Mtv44 to the centromeric region of mouse Chromosome 11, MAMMALIAN GENOME, Vol: 7, Pages: 319-320, ISSN: 0938-8990

Journal article

Hederer RA, Chandler PR, Dyson PJ, Antoniou AN, Millrain MM, Mellor AL, Simpson E, Robinson PJet al., 1996, Acceptance of skin grafts between mice bearing different allelic forms of beta(2)-microglobulin, TRANSPLANTATION, Vol: 61, Pages: 299-304, ISSN: 0041-1337

Journal article

Simpson E, 1996, Immunology: Why the baby isn't thrown out ..., CURRENT BIOLOGY, Vol: 6, Pages: 43-44, ISSN: 0960-9822

Journal article

Mamalaki C, Murdjeva M, Tolaini M, Norton T, Chandler P, Townsend A, Simpson E, Kioussis Det al., 1996, Tolerance in TCR cognate antigen double-transgenic mice mediated by incomplete thymic deletion and peripheral receptor downregulation, DEVELOPMENTAL IMMUNOLOGY, Vol: 4, Pages: 299-315, ISSN: 1044-6672

Journal article

Slingsby JH, Hogarth MB, Simpson E, Walport MJ, Morley BJet al., 1996, New microsatellite polymorphisms identified between C57BL/6, C57BL/10, and C57BL/KsJ inbred mouse strains, IMMUNOGENETICS, Vol: 43, Pages: 72-75, ISSN: 0093-7711

Journal article

SIMPSON E, CHANDLER P, SPONAAS A, MILLRAIN M, DYSON PJet al., 1995, T-CELLS WITH DUAL ANTIGEN-SPECIFICITY IN T-CELL RECEPTOR TRANSGENIC MICE REJECTING ALLOGRAFTS, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 25, Pages: 2813-2817, ISSN: 0014-2980

Journal article

CHANDLER P, FRATER AJ, DOUEK DC, VINEY JL, KAY G, OWEN MJ, HAYDAY AC, SIMPSON E, ALTMANN DMet al., 1995, IMMUNE RESPONSIVENESS IN MUTANT MICE LACKING T-CELL RECEPTOR ALPHA-BETA(+) CELLS, IMMUNOLOGY, Vol: 85, Pages: 531-537, ISSN: 0019-2805

Journal article

VAJKOCZY P, MENGER MD, SIMPSON E, MESSMER Ket al., 1995, ANGIOGENESIS AND VASCULARIZATION OF MURINE PANCREATIC-ISLET ISOGRAFTS, TRANSPLANTATION, Vol: 60, Pages: 123-127, ISSN: 0041-1337

Journal article

QUARTEYPAPAFIO R, LUND T, CHANDLER P, PICARD J, OZEGBE P, DAY S, HUTCHINGS PR, OREILLY L, KIOUSSIS D, SIMPSON E, COOKE Aet al., 1995, ASPARTATE AT POSITION 57 OF NONOBESE DIABETIC I-A(G7) BETA-CHAIN DIMINISHES THE SPONTANEOUS INCIDENCE OF INSULIN-DEPENDENT DIABETES-MELLITUS, JOURNAL OF IMMUNOLOGY, Vol: 154, Pages: 5567-5575, ISSN: 0022-1767

Journal article

COLUCCI F, DAHL U, OREILLY L, COOKE A, CHANDLER P, SIMPSON E, MATSUNAGA Tet al., 1994, NON-DIABETOGENIC INSULITIS IN NOD[--]B1O.GD ALLOPHENIC MICE IN SPITE OF PERMISSIVE CLASS-I MHC ANTIGENS, SCANDINAVIAN JOURNAL OF IMMUNOLOGY, Vol: 40, Pages: 659-664, ISSN: 0300-9475

Journal article

KING TR, CHRISTIANSON GJ, MITCHELL MJ, BISHOP CE, SCOTT D, EHRMANN I, SIMPSON E, EICHER EM, ROOPENIAN DCet al., 1994, DELETION MAPPING BY IMMUNOSELECTION AGAINST THE H-Y HISTOCOMPATIBILITY ANTIGEN FURTHER RESOLVES THE SXR(A) REGION OF THE MOUSE Y-CHROMOSOME AND REVEALS COMPLEXITY OF THE HYA LOCUS, GENOMICS, Vol: 24, Pages: 159-168, ISSN: 0888-7543

Journal article

OREILLY LA, HEALEY D, SIMPSON E, CHANDLER P, LUND T, RITTER MA, COOKE Aet al., 1994, STUDIES ON THE THYMUS OF NONOBESE DIABETIC (NOD) MICE - EFFECT OF TRANSGENE EXPRESSION, IMMUNOLOGY, Vol: 82, Pages: 275-286, ISSN: 0019-2805

Journal article

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00328399&limit=30&person=true&page=3&respub-action=search.html