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@article{Rajgor:2021:10.1259/bjr.20210499,
author = {Rajgor, AD and Patel, S and Mcculloch, D and Obara, B and Bacardit, J and Mcqueen, A and Aboagye, E and Ali, T and O'Hara, J and Hamilton, DW},
doi = {10.1259/bjr.20210499},
journal = {British Journal of Radiology},
pages = {1--13},
title = {The application of radiomics in laryngeal cancer},
url = {http://dx.doi.org/10.1259/bjr.20210499},
volume = {94},
year = {2021}
}

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TY  - JOUR
AB  - Objectives:Radiomics is the conversion of medical images into quantitative high-dimensional data. Laryngeal cancer, one of the most common head and neck cancers, has risen globally by 58.7%. CT, MRI and PET are acquired during the diagnostic process providing potential data for radiomic analysis and correlation with outcomes.This review aims to examine the applications of this technique to laryngeal cancer and the future considerations for translation into clinical practice.Methods:A comprehensive systematic review-informed search of the MEDLINE and EMBASE databases was undertaken. Keywords “laryngeal cancer” OR “larynx“ OR “larynx cancer” OR “head and neck cancer” were combined with “radiomic” OR “signature” OR “machine learning” OR “artificial intelligence”. Additional articles were obtained from bibliographies using the “snowball method”.Results:The included studies (n = 15) demonstrated that radiomic features are significantly associated with various clinical outcomes (including stage, overall survival, treatment response, progression-free survival) and that predictive models incorporating radiomic features are superior to those that do not. Two studies demonstrated radiomics could improve laryngeal cancer staging whilst 12 studies affirmed its predictive capability for clinical outcomes.Conclusions:Radiomics has potential for improving multiple aspects of laryngeal cancer care; however, the heterogeneous cohorts and lack of data on laryngeal cancer exclusively inhibits firm conclusions. Large prospective well-designed studies in laryngeal cancer are required to progress this field. Furthermore, to implement radiomics into clinical practice, a unified research effort is required to standardise radiomics practice.Advances in knowledge:This review has highlighted the value of radiomics in enhancing laryngeal cancer care (including staging, prognosis and pred
AU  - Rajgor,AD
AU  - Patel,S
AU  - Mcculloch,D
AU  - Obara,B
AU  - Bacardit,J
AU  - Mcqueen,A
AU  - Aboagye,E
AU  - Ali,T
AU  - O'Hara,J
AU  - Hamilton,DW
DO  - 10.1259/bjr.20210499
EP  - 13
PY  - 2021///
SN  - 0007-1285
SP  - 1
TI  - The application of radiomics in laryngeal cancer
T2  - British Journal of Radiology
UR  - http://dx.doi.org/10.1259/bjr.20210499
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000721546400003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://www.birpublications.org/doi/10.1259/bjr.20210499
UR  - http://hdl.handle.net/10044/1/101516
VL  - 94
ER  -

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