Imperial College London
Alternate

ProfessorEricAboagye

Faculty of Medicine, Department of Surgery & Cancer

Professor
 
 
 
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Contact

 

+44 (0)20 3313 3759eric.aboagye

 
 
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Assistant

 

Mrs Maureen Francis +44 (0)20 7594 2793

 
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Location

 

GN1Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Amgheib:2022:10.3390/pharmaceutics14102040,
author = {Amgheib, A and Fu, R and Aboagye, EO},
doi = {10.3390/pharmaceutics14102040},
journal = {Pharmaceutics},
pages = {1--31},
title = {Positron emission tomography probes for imaging cytotoxic immune cells},
url = {http://dx.doi.org/10.3390/pharmaceutics14102040},
volume = {14},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Non-invasive positron emission tomography (PET) imaging of immune cells is a powerful approach for monitoring the dynamics of immune cells in response to immunotherapy. Despite the clinical success of many immunotherapeutic agents, their clinical efficacy is limited to a subgroup of patients. Conventional imaging, as well as analysis of tissue biopsies and blood samples do not reflect the complex interaction between tumour and immune cells. Consequently, PET probes are being developed to capture the dynamics of such interactions, which may improve patient stratification and treatment evaluation. The clinical efficacy of cancer immunotherapy relies on both the infiltration and function of cytotoxic immune cells at the tumour site. Thus, various immune biomarkers have been investigated as potential targets for PET imaging of immune response. Herein, we provide an overview of the most recent developments in PET imaging of immune response, including the radiosynthesis approaches employed in their development.
AU  - Amgheib,A
AU  - Fu,R
AU  - Aboagye,EO
DO  - 10.3390/pharmaceutics14102040
EP  - 31
PY  - 2022///
SN  - 1999-4923
SP  - 1
TI  - Positron emission tomography probes for imaging cytotoxic immune cells
T2  - Pharmaceutics
UR  - http://dx.doi.org/10.3390/pharmaceutics14102040
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000873871500001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://www.mdpi.com/1999-4923/14/10/2040
UR  - http://hdl.handle.net/10044/1/101321
VL  - 14
ER  -
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