Imperial College London
Portrait Picture

Eric Lim

Faculty of Medicine, National Heart & Lung Institute

Professor of Thoracic Surgery
 
 
 
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Contact

 

+44 (0)20 7351 8591eric.lim

 
 
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Location

 

Sydney StreetRoyal Brompton Campus

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Summary

 

Publications

Publication Type
Year
to

302 results found

McElnay P, Lim E, 2014, Adjuvant or neoadjuvant chemotherapy for NSCLC, JOURNAL OF THORACIC DISEASE, Vol: 6, Pages: S224-S227, ISSN: 2072-1439

Journal article

Clark SJ, Zoumot Z, Bamsey O, Polkey MI, Dusmet M, Lim E, Jordan S, Hopkinson NSet al., 2014, Surgical approaches for lung volume reduction in emphysema, CLINICAL MEDICINE, Vol: 14, Pages: 122-127, ISSN: 1470-2118

Journal article

Ruffini E, Detterbeck F, Van Raemdonck D, Rocco G, Thomas P, Weder W, Brunelli A, Guerrera F, Keshavjee S, Altorki N, Schuetzner J, Arame A, Spaggiari L, Lim E, Toker A, Venuta Fet al., 2014, Thymic Carcinoma: A Cohort Study of Patients from the European Society of Thoracic Surgeons Database, JOURNAL OF THORACIC ONCOLOGY, Vol: 9, Pages: 541-548, ISSN: 1556-0864

Journal article

Treasure T, Dusmet M, Fiorentino F, Lim E, Waller D, Lees Bet al., 2014, Surgery for malignant pleural mesothelioma: why we need controlled trials, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 45, Pages: 591-592, ISSN: 1010-7940

Journal article

Luechtenborg M, Riaz SP, Lim E, Page R, Baldwin DR, Jakobsen E, Vedsted P, Lind M, Peake MD, Mellemgaard A, Spicer J, Lang-Lazdunski L, Moller Het al., 2014, Survival of patients with small cell lung cancer undergoing lung resection in England, 1998-2009, Thorax, Vol: 69, Pages: 269-273, ISSN: 1468-3296

IntroductionChemotherapy or chemoradiotherapy isthe recommended treatment for small cell lung cancer(SCLC), except in stage I disease where clinicalguidelines state there may be a role for surgery based onfavourable outcomes in case series. Evidence supportingadjuvant chemotherapy in resected SCLC is limited butthis is widely offered.MethodsData on 359 873 patients who werediagnosed with afirst primary lung cancer in Englandbetween 1998 and 2009 were grouped according tohistology (SCLC or non-SCLC (NSCLC)) and whether theyunderwent a surgical resection. We explored theirsurvival using Kaplan–Meier analysis and Cox regression,adjusting for age, sex, comorbidity and socioeconomicstatus.ResultsThe survival of 465 patients with resectedSCLC was lower than patients with resected NSCLC(5-year survival 31% and 45%, respectively), but muchhigher than patients of either group who were notresected (3%). The difference between resected SCLCand NSCLC diminished with time after surgery. Survivalwas superior for the subgroup of 198‘elective’SCLCcases where the diagnosis was most likely known beforeresection than for the subgroup of 267‘incidental’caseswhere the SCLC diagnosis was likely to have been madeafter resection.ConclusionsThese data serve as a natural experimenttesting the survival after surgical management of SCLCaccording to NSCLC principles. Patients with SCLCtreated surgically for early stage disease may havesurvival outcomes that approach those of NSCLC,supporting the emerging clinical practice of offeringsurgical resection to selected patients with SCLC.

Journal article

Bari MF, Brown H, Nicholson AG, Kerr KM, Gosney JR, Wallace WA, Soomro I, Muller S, Peat D, Moore JD, Ward LA, Freidin MB, Lim E, Vatish M, Snead DRJet al., 2014, BAI3, CDX2 and VIL1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas, HISTOPATHOLOGY, Vol: 64, Pages: 547-556, ISSN: 0309-0167

Journal article

Freidin MB, Mair D, Tay A, Freydina DV, Chudasama D, Popat S, Nicholson AG, Rice A, Montero-Fernandez A, Anikin V, de Castro DG, Lim Eet al., 2014, The utility of peripheral blood circulating tumour cells for the detection of <i>KRAS</i>, <i>EGFR</i> and <i>BRAF</i> mutations in primary lung, Publisher: ELSEVIER IRELAND LTD, Pages: S3-S4, ISSN: 0169-5002

Conference paper

Freydina DV, Tay A, Chudasama D, Freidin MB, Nicholson AG, Rice A, Montero-Fernandez A, Popat S, Anikin V, Lim Eet al., 2014, The ability of a filter-based antibody-independent approach to capture circulating tumour cells for the diagnosis of lung cancer, Publisher: ELSEVIER IRELAND LTD, Pages: S17-S18, ISSN: 0169-5002

Conference paper

Sethi T, Lim E, Peake M, Field J, White J, Nicolson M, Faivre-Finn C, Cane P, Reynolds J, Moller H, Pinnock Het al., 2013, Improving care for patients with lung cancer in the UK, THORAX, Vol: 68, Pages: 1181-1185, ISSN: 0040-6376

Journal article

Detterbeck FC, Asamura H, Crowley J, Falkson C, Giaccone G, Giroux D, Huang J, Kim J, Kondo K, Lucchi M, Marino M, Marom EM, Nicholson A, Okumura M, Ruffini E, van Schil P, Stratton Ket al., 2013, The IASLC/ITMIG Thymic Malignancies Staging Project <i>Development of a Stage Classification for Thymic Malignancies</i>, JOURNAL OF THORACIC ONCOLOGY, Vol: 8, Pages: 1467-1473, ISSN: 1556-0864

Journal article

Freydina DV, Tay A, Chudasama D, Freidin MB, Nicholson AG, Rice A, Montero-Fernandez A, Popat S, Anikin V, Lim Eet al., 2013, DIAGNOSTIC PERFORMANCE OF A FILTER-BASED ANTIBODY-INDEPENDENT PERIPHERAL BLOOD CIRCULATING TUMOUR CELL CAPTURE PAIRED WITH CYTOMORPHOLOGIC CRITERIA FOR THE DIAGNOSIS OF LUNG CANCER, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S1278-S1278, ISSN: 1556-0864

Conference paper

Freidin MB, Mair D, Tay A, Freydina DV, Chudasama D, Popat S, Nicholson AG, Rice A, Montero-Fernandez A, Anikin V, De Castro DG, Lim Eet al., 2013, THE EFFICIENCY OF DETECTION OF KRAS, EGFR AND BRAF MUTATIONS IN PRIMARY LUNG CANCER VIA PERIPHERAL BLOOD CIRCULATING TUMOUR CELLS, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: S456-S456, ISSN: 1556-0864

Conference paper

Pattenden H, Leung M, Beddow E, Dusmet M, Nicholson AG, Shackcloth M, Mohamed S, Darr A, Naidu B, Iyer S, Marchbank A, Greenwood A, West D, Granato F, Kirk A, Lim E, Ariyaratnam P, Loubani Met al., 2013, TEST PERFORMANCE OF PET-CT FOR MEDIASTINAL LYMPH NODE STAGING OF PULMONARY CARCINOID TUMOURS, JOURNAL OF THORACIC ONCOLOGY, Vol: 8, Pages: S676-S677, ISSN: 1556-0864

Journal article

Vansteenkiste J, De Ruysscher D, Eberhardt WEE, Lim E, Senan S, Felip E, Peters Set al., 2013, Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up, ANNALS OF ONCOLOGY, Vol: 24, Pages: 89-98, ISSN: 0923-7534

Journal article

Luechtenborg M, Riaz SP, Coupland VH, Lim E, Jakobsen E, Krasnik M, Page R, Lind MJ, Peake MD, Moller Het al., 2013, High Procedure Volume Is Strongly Associated With Improved Survival After Lung Cancer Surgery, JOURNAL OF CLINICAL ONCOLOGY, Vol: 31, Pages: 3141-+, ISSN: 0732-183X

Journal article

Clark S, Zoumot Z, Davey C, Purcell H, Bamsey O, Polkey M, Dusmet M, Lim E, Jordan S, Hopkinson Net al., 2013, 12 years of thoracic surgery for emphysema at The Royal Brompton Hospital, EUROPEAN RESPIRATORY JOURNAL, Vol: 42, ISSN: 0903-1936

Journal article

Lim E, Popat S, 2013, What exactly are we doing to improve low lung cancer survival in the United Kingdom?, THORAX, Vol: 68, Pages: 504-505, ISSN: 0040-6376

Journal article

Pattenden H, Beddow E, Dusmet M, Nicholson AG, Greenwood A, West DJ, Ariyaratnam P, Loubani M, Lim Eet al., 2013, Test performance of PET-CT for mediastinal lymph node staging of pulmonary carcinoid tumours, LUNG CANCER, Vol: 79, Pages: S20-S20, ISSN: 0169-5002

Journal article

Freidin MB, Tay A, Chudasama D, Nicholson AG, Rice A, Bamsey O, Higgins A, Popat S, Anikin V, Lim Eet al., 2013, Non-invasive KRAS and EGFR mutation testing of primary lung cancer via peripheral blood circulating tumour cells, Publisher: ELSEVIER IRELAND LTD, Pages: S5-S6, ISSN: 0169-5002

Conference paper

von der Thusen JH, Tham YS, Pattenden H, Rice A, Dusmet M, Lim E, Nicholson AGet al., 2013, Prognostic Significance of Predominant Histologic Pattern and Nuclear Grade in Resected Adenocarcinoma of the Lung <i>Potential Parameters for a Grading System</i>, JOURNAL OF THORACIC ONCOLOGY, Vol: 8, Pages: 37-44, ISSN: 1556-0864

Journal article

Clark SJ, Zoumot Z, Davey C, Purcell H, Bamsey O, Polkey MI, Dusmet M, Lim E, Jordan S, Hopkinson NSet al., 2013, Mortality Data Following Lung Volume Reduction Surgery At The Royal Brompton Hospital, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 187, ISSN: 1073-449X

Journal article

Lim E, Tay A, Nicholson AG, 2012, Antibody Independent Microfluidic Cell Capture of Circulating Tumor Cells for the Diagnosis of Cancer, JOURNAL OF THORACIC ONCOLOGY, Vol: 7, Pages: E42-E43, ISSN: 1556-0864

Journal article

Cheung IHW, Lim E, 2012, Video-assisted thoracoscopic surgical lobectomy with limited en bloc resection of superior sulcus tumor, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol: 144, Pages: E148-E151, ISSN: 0022-5223

Journal article

Vallieres E, Peters S, Van Houtte P, Dalal P, Lim Eet al., 2012, Therapeutic advances in non-small cell lung cancer, THORAX, Vol: 67, Pages: 1097-1101, ISSN: 0040-6376

Journal article

Lim E, 2012, Patients' Perspective in the Surgical Decision-Making Process, THORACIC SURGERY CLINICS, Vol: 22, Pages: 539-+, ISSN: 1547-4127

Journal article

Popat R, Derodra J, Vig S, Lim Eet al., 2012, A sinister cause of shoulder pain, with numbness and weakness in the ipsilateral hand, BRITISH MEDICAL JOURNAL, Vol: 345, ISSN: 1756-1833

Journal article

Green AC, Mason M, Lim E, Jordan S, Ladas G, Dusmet M, Rice A, Nicholson AGet al., 2012, Type a thymomas: histological features associated with aggressive behaviour, 29th Congress of the International-Academy-of-Pathology, Publisher: WILEY-BLACKWELL, Pages: 204-204, ISSN: 0309-0167

Conference paper

Gatheral T, Reed DM, Moreno L, Gough PJ, Votta BJ, Sehon CA, Rickard DJ, Bertin J, Lim E, Nicholson AG, Mitchell JAet al., 2012, A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses, PLOS ONE, Vol: 7, ISSN: 1932-6203

Journal article

Bille A, Barker A, Maratos EC, Edmonds L, Lim Eet al., 2012, Surgical access rather than method of pleurodesis (pleurectomy or pleural abrasion) influences recurrence rates for pneumothorax surgery: systematic review and meta-analysis., Gen Thorac Cardiovasc Surg, Vol: 60, Pages: 321-325

AIM: Surgery for recurrent spontaneous pneumothoraces is one of the most commonly performed procedures in thoracic surgery, but few studies have evaluated the efficacy of the surgical treatment options. We aimed to evaluate the influence of the type of pleurodesis on recurrence whilst adjusting for surgical access by systematic review and meta-regression of randomised and non-randomised trials. METHODS: A systematic literature search undertaken for studies on pneumothorax surgery in MEDLINE, EMBASE, Cochrane Library, Internet trial registers and conference abstracts identified 29 studies (4 randomised and 25 non-randomised) eligible for inclusion. Meta-regression was performed adjusting for access to screen for evidence of a difference in recurrence rates. RESULTS: Access remained the principal determinant of recurrence rates after surgery. The relative risk of recurrence was 4.731 (2.699-8.291; p < 0.001) using video-assisted thoracoscopic surgery compared to open access. After adjusting for access, the relative risk of recurrence of pleural abrasion compared to pleurectomy was observed to be 2.851 (95 % CI 0.478-17.021), but this was not statistically (p = 0.220). CONCLUSION: Surgical access remains the most important factor that influences outcome after surgery for recurrent pneumothoraces. Although the relative risk of recurrence was higher with pleural abrasion compared to pleurectomy, it was not statistically significant, and more work needs to be conducted to address this question.

Journal article

Freidin MB, Bhudia N, Lim E, Nicholson AG, Cookson WO, Moffatt MFet al., 2012, Impact of Collection and Storage of Lung Tumor Tissue on Whole Genome Expression Profiling, JOURNAL OF MOLECULAR DIAGNOSTICS, Vol: 14, Pages: 140-148, ISSN: 1525-1578

Journal article

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