Imperial College London
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Eric Lim

Faculty of Medicine, National Heart & Lung Institute

Professor of Thoracic Surgery
 
 
 
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Contact

 

+44 (0)20 7351 8591eric.lim

 
 
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Location

 

Sydney StreetRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Baudin:2019:10.1159/000493980,
author = {Baudin, E and Hayes, A and Scoazec, J-Y and Filosso, PL and Lim, E and Kaltsas, G and Frilling, A and Chen, J and Kos-Kudla, B and Gorbounova, V and Wiedenmann, B and Nieveen, van Dijkum E and Cwikla, J and Falkerby, J and Valle, JW and Kulke, MH and Caplin, M},
doi = {10.1159/000493980},
journal = {Neuroendocrinology},
pages = {7--17},
title = {Unmet medical needs in pulmonary neuroendocrine (carcinoid) neoplasms},
url = {http://dx.doi.org/10.1159/000493980},
volume = {108},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Pulmonary carcinoids (PCs) display the common features of all well-differentiated neuroendocrine neoplasms (NEN) and are classified as low- and intermediate-grade malignant tumours (i.e. typical (TC) and atypical carcinoid (AC), respectively). There is a paucity of randomised studies dedicated to advanced PCs and management principles are drawn from the larger gastroenteropancreatic (GEP) NEN experience. There is growing evidence that NEN anatomic subgroups have different biology and different responses to treatment and, therefore, should be investigated as separate entities in clinical trials. In this review, we discuss the existing evidence and limitations of tumour classification, diagnostics and staging, prognostication and treatment in the setting of PC with focus on unmet medical needs and directions for the future.
AU  - Baudin,E
AU  - Hayes,A
AU  - Scoazec,J-Y
AU  - Filosso,PL
AU  - Lim,E
AU  - Kaltsas,G
AU  - Frilling,A
AU  - Chen,J
AU  - Kos-Kudla,B
AU  - Gorbounova,V
AU  - Wiedenmann,B
AU  - Nieveen,van Dijkum E
AU  - Cwikla,J
AU  - Falkerby,J
AU  - Valle,JW
AU  - Kulke,MH
AU  - Caplin,M
DO  - 10.1159/000493980
EP  - 17
PY  - 2019///
SN  - 0028-3835
SP  - 7
TI  - Unmet medical needs in pulmonary neuroendocrine (carcinoid) neoplasms
T2  - Neuroendocrinology
UR  - http://dx.doi.org/10.1159/000493980
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30248673
UR  - http://hdl.handle.net/10044/1/64851
VL  - 108
ER  -
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