Drug Resistance Group
My research interests centre on molecular mechanisms of resistance to cancer chemotherapy and more in particular on the role of micro RNAs on breast cancer.
MRes in Cancer Biology Stream Director
I also supervise several PhD and post-graduate students and collaborate in the Faculty of Medicine undergraduate teaching and tutoring.
I obtained the degree of Doctor in Biology by the Complutense University (Madrid). After post-doctoral positions at the Pasteur Institute (Paris), King's College (London) and in the biotech industry, I joined Prof. Christopher Higgins' laboratory at the Medical Research Council as a senior research scientist working on drug resistance. I moved to Imperial College in October 2007.
et al., 2024, Exploring the histogenesis of STK11 adnexal tumour using electron microscopy., Virchows Arch
et al., 2023, Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC, Cell Communication and Signaling, Vol:21, ISSN:1478-811X
et al., 2023, Adaptive resistance is not responsible for long-term drug resistance in a cellular model of triple negative breast cancer, Gene, Vol:850, ISSN:0378-1119
et al., 2022, The miR-106b-25 cluster mediates drug resistance in myeloid leukaemias by inactivating multiple apoptotic genes, International Journal of Hematology, ISSN:0925-5710, Pages:1-15
Yagüe E, Sun H, Hu Y, 2022, East Wind, West Wind: Toward the modernization of traditional Chinese medicine., Frontiers in Neuroscience, Vol:16, ISSN:1662-453X, Pages:1-17